LGR4 leucine rich repeat containing G protein-coupled receptor 4 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: LGR4provided by VGNC
Official Full Name: leucine rich repeat containing G protein-coupled receptor 4provided by VGNC
Primary source: VGNC:VGNC:42655
See related: Ensembl:ENSCAFG00845017676
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	21	NC_051825.1 (49092130..49194350, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	21	NC_006603.4 (47448894..47548000, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	21	NC_049242.1 (48839453..48939290, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	21	NC_049281.1 (48077244..48176850, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	21	NC_049762.1 (48247673..48347510, complement)

Chromosome 21 - NC_051825.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein-hormone receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: leucine-rich repeat-containing G-protein coupled receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051825.1 Reference ROS_Cfam_1.0

Range

49092130..49194350 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038430726.1 → XP_038286654.1 leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1

UniProtKB/TrEMBL

A0A8C0PKD6

Related

ENSCAFP00845024494.1, ENSCAFT00845031291.1

Conserved Domains (4) summary

sd00033
Location:18 → 41

LRR_RI; leucine-rich repeat [structural motif]

cd15361
Location:474 → 747

7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors

NF033189
Location:40 → 398

internalin_A; class 1 internalin InlA

pfam13855
Location:2 → 52

LRR_8; Leucine rich repeat

Alternate UMICH_Zoey_3.1

Genomic

NC_049281.1 Alternate UMICH_Zoey_3.1

Range

48077244..48176850 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038506051.1 → XP_038361979.1 leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2

Conserved Domains (3) summary

PLN00113
Location:34 → 445

PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

sd00033
Location:59 → 82

LRR_RI; leucine-rich repeat [structural motif]

cd15361
Location:539 → 812

7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049762.1 Alternate UNSW_CanFamBas_1.0

Range

48247673..48347510 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038633476.1 → XP_038489404.1 leucine-rich repeat-containing G-protein coupled receptor 4 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049242.1 Alternate UU_Cfam_GSD_1.0

Range

48839453..48939290 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038569287.1 → XP_038425215.1 leucine-rich repeat-containing G-protein coupled receptor 4 isoform X4

UniProtKB/TrEMBL

A0A8C0Q6X4, A0A8C0QD14, A0A8P0SF16

Conserved Domains (3) summary

PLN00113
Location:34 → 445

PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

sd00033
Location:59 → 82

LRR_RI; leucine-rich repeat [structural motif]

cd15361
Location:539 → 812

7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

47448894..47548000 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038456513.1 → XP_038312441.1 leucine-rich repeat-containing G-protein coupled receptor 4 isoform X5

UniProtKB/TrEMBL

A0A8C0Q6X4, A0A8C0QD14, A0A8P0SF16

Conserved Domains (3) summary

PLN00113
Location:34 → 445

PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

sd00033
Location:59 → 82

LRR_RI; leucine-rich repeat [structural motif]

cd15361
Location:539 → 812

7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors