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RHEB Ras homolog, mTORC1 binding [ Canis lupus familiaris (dog) ]

Gene ID: 475545, updated on 5-Mar-2024

Summary

Official Symbol
RHEBprovided by VGNC
Official Full Name
Ras homolog, mTORC1 bindingprovided by VGNC
Primary source
VGNC:VGNC:45551
See related
Ensembl:ENSCAFG00845011138
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (17162021..17205547, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (16047342..16090853, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (16166245..16209781, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 16 NC_049276.1 (15534296..15577817, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (16115524..16159011, complement)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 86 Neighboring gene uncharacterized LOC111090255 Neighboring gene crystallin gamma N Neighboring gene microtubule-associated protein RP/EB family member 1-like Neighboring gene uncharacterized LOC119869554 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
GTP-binding protein Rheb
Names
Ras homolog enriched in brain
XP_022259589.1
XP_038353260.1
XP_038353261.1
XP_038415692.1
XP_038415693.1
XP_038479680.1
XP_038479682.1
XP_038545458.1
XP_038545459.1
XP_532768.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    17162021..17205547 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038689530.1XP_038545458.1  GTP-binding protein Rheb isoform X1

    UniProtKB/TrEMBL
    A0A8C0JXV7, A0A8C0P6P0, A0A8I3N749
    Related
    ENSCAFP00845015492.1, ENSCAFT00845019791.1
    Conserved Domains (1) summary
    cd04137
    Location:6184
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
  2. XM_038689531.1XP_038545459.1  GTP-binding protein Rheb isoform X2

    Conserved Domains (1) summary
    cd04137
    Location:6154
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049276.1 Alternate UMICH_Zoey_3.1

    Range
    15534296..15577817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038497332.1XP_038353260.1  GTP-binding protein Rheb isoform X1

    Conserved Domains (1) summary
    cd04137
    Location:6184
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
  2. XM_038497333.1XP_038353261.1  GTP-binding protein Rheb isoform X2

    Conserved Domains (1) summary
    cd04137
    Location:6154
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    16115524..16159011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623752.1XP_038479680.1  GTP-binding protein Rheb isoform X1

    Conserved Domains (1) summary
    cd04137
    Location:6184
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
  2. XM_038623754.1XP_038479682.1  GTP-binding protein Rheb isoform X2

    Conserved Domains (1) summary
    cd04137
    Location:6154
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    16166245..16209781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559764.1XP_038415692.1  GTP-binding protein Rheb isoform X1

    UniProtKB/TrEMBL
    A0A8C0JXV7, A0A8C0P6P0, A0A8I3N749
    Conserved Domains (1) summary
    cd04137
    Location:6184
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
  2. XM_038559765.1XP_038415693.1  GTP-binding protein Rheb isoform X2

    Conserved Domains (1) summary
    cd04137
    Location:6154
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16047342..16090853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_532768.5XP_532768.1  GTP-binding protein Rheb isoform X1

    See identical proteins and their annotated locations for XP_532768.1

    UniProtKB/TrEMBL
    A0A8C0JXV7, A0A8C0P6P0, A0A8I3N749
    Conserved Domains (1) summary
    cd04137
    Location:6184
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase
  2. XM_022403881.2XP_022259589.1  GTP-binding protein Rheb isoform X2

    Conserved Domains (1) summary
    cd04137
    Location:6154
    RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase