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CASP2 caspase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463804, updated on 3-Apr-2024

Summary

Official Symbol
CASP2provided by VGNC
Official Full Name
caspase 2provided by VGNC
Primary source
VGNC:VGNC:4294
Locus tag
CK820_G0014123
See related
Ensembl:ENSPTRG00000019805 Ensembl:ENSPTRG00000047033
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See CASP2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (158694795..158715566)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (152760790..152781566)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene Kell metallo-endopeptidase Neighboring gene taste 2 receptor member 40 Neighboring gene glutathione S-transferase kappa 1 Neighboring gene adenosine 5'-monophosphoramidase HINT1-like Neighboring gene transmembrane protein 139 Neighboring gene chloride voltage-gated channel 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
PubMed 
enables death domain binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
caspase-2
Names
caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)
XP_016800926.3
XP_016800927.3
XP_054511223.2
XP_054511225.2
XP_054511227.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    158694795..158715566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054655248.2XP_054511223.2  caspase-2 isoform X2

  2. XM_016945437.4XP_016800926.3  caspase-2 isoform X1

    UniProtKB/TrEMBL
    A0A2J8QUG9, A0A6D2W4D6, H2QVJ4
  3. XM_016945438.4XP_016800927.3  caspase-2 isoform X3

  4. XM_054655250.2XP_054511225.2  caspase-2 isoform X4

  5. XM_054655252.2XP_054511227.2  caspase-2 isoform X5

RNA

  1. XR_010159033.1 RNA Sequence