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IL6 interleukin 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463288, updated on 10-Oct-2024

Summary

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Official Symbol
IL6provided by VGNC
Official Full Name
interleukin 6provided by VGNC
Primary source
VGNC:VGNC:4400
Locus tag
CK820_G0034715
See related
Ensembl:ENSPTRG00000018979 Ensembl:ENSPTRG00000050502
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See IL6 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (28552901..28559109)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (26328450..26333327)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene STEAP family member 1B Neighboring gene uncharacterized LOC107975731 Neighboring gene small ribosomal subunit protein eS26-like Neighboring gene translocase of outer mitochondrial membrane 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-6 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T-helper 17 cell lineage commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of interleukin-6 receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-6
Names
interleukin 6 (interferon, beta 2)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    28552901..28559109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063815261.1 → XP_063671331.1  interleukin-6 isoform X2

    UniProtKB/TrEMBL
    A0A2J8KZJ7, A0A6D2Y6D5, H2QU89

  2. XM_009452755.5 → XP_009451030.1  interleukin-6 isoform X1

    Conserved Domains (1) summary
    cl02473
    Location:87 → 212
    IL6; Interleukin-6/G-CSF/MGF family

  3. XM_518992.8 → XP_518992.2  interleukin-6 isoform X2

    See identical proteins and their annotated locations for XP_518992.2

    UniProtKB/TrEMBL
    A0A2I3RKA9, A0A2J8KZJ7, A0A6D2Y6D5, H2QU89
    Related
    ENSPTRP00000032433.4
    Conserved Domains (1) summary
    pfam00489
    Location:33 → 211
    IL6; Interleukin-6/G-CSF/MGF family

  4. XM_016945535.3 → XP_016801024.1  interleukin-6 isoform X3

    UniProtKB/TrEMBL
    A0A2J8KZI6
    Conserved Domains (1) summary
    cl02473
    Location:1 → 135
    IL6; Interleukin-6/G-CSF/MGF family
Nucleotide Protein
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