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IL6 interleukin 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463288, updated on 2-Nov-2023

Summary

Official Symbol
IL6provided by VGNC
Official Full Name
interleukin 6provided by VGNC
Primary source
VGNC:VGNC:4400
Locus tag
CK820_G0034715
See related
Ensembl:ENSPTRG00000018979 Ensembl:ENSPTRG00000050502
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See IL6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (26328450..26333327)

Chromosome 7 - NC_072405.1Genomic Context describing neighboring genes Neighboring gene STEAP family member 1B Neighboring gene uncharacterized LOC107975731 Neighboring gene 40S ribosomal protein S26-like Neighboring gene translocase of outer mitochondrial membrane 7

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072405.1 Chromosome 7 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables interleukin-6 receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in T-helper 17 cell lineage commitment IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
interleukin-6
Names
interleukin 6 (interferon, beta 2)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072405.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    26328450..26333327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_518992.7XP_518992.2  interleukin-6 isoform X2

    See identical proteins and their annotated locations for XP_518992.2

    UniProtKB/TrEMBL
    A0A2I3RKA9, A0A2J8KZJ7, A0A6D2Y6D5, H2QU89
    Related
    ENSPTRP00000032433.4
    Conserved Domains (1) summary
    pfam00489
    Location:33211
    IL6; Interleukin-6/G-CSF/MGF family
  2. XM_009452755.4XP_009451030.1  interleukin-6 isoform X1

    Conserved Domains (1) summary
    cl02473
    Location:87212
    IL6; Interleukin-6/G-CSF/MGF family
  3. XM_016945535.2XP_016801024.1  interleukin-6 isoform X3

    UniProtKB/TrEMBL
    A0A2J8KZI6
    Conserved Domains (1) summary
    cl02473
    Location:1135
    IL6; Interleukin-6/G-CSF/MGF family