CA2 carbonic anhydrase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CA2provided by VGNC
Official Full Name: carbonic anhydrase 2provided by VGNC
Primary source: VGNC:VGNC:10214
Locus tag: CK820_G0027326
See related: Ensembl:ENSPTRG00000020389
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	7	NC_072405.2 (94128060..94145522)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	8	NC_072406.1 (99149945..99167414)

Chromosome 7 - NC_072405.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH11468 (e-PCR)
- UniSTS:23717

G44354 (e-PCR)
- UniSTS:95141

D8S1418E (e-PCR)
- UniSTS:151206

G60153 (e-PCR)
- UniSTS:137408

D8S1912 (e-PCR)
- UniSTS:19667

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in carbon dioxide transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of intracellular pH	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in apical part of cell	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: carbonic anhydrase 2

Names: carbonic anhydrase II

NP_001181853.1

EC 4.2.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001194924.1 → NP_001181853.1 carbonic anhydrase 2

See identical proteins and their annotated locations for NP_001181853.1

Status: PROVISIONAL

Source sequence(s)

AY369788, DC519797, JAQQLN020000007

UniProtKB/TrEMBL

A0A2I3SU51, A0A2J8LP62, A0A6D2VTJ2, H2QWD5

Related

ENSPTRP00000034879.3, ENSPTRT00000037736.4

Conserved Domains (1) summary

cd03119
Location:1 → 259

alpha_CA_I_II_III_XIII; Carbonic anhydrase alpha, isozymes I, II, and III and XIII. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on ...