kif2c kinesin family member 2C [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: kif2cprovided by Xenbase
Official Full Name: kinesin family member 2Cprovided by Xenbase
Primary source: Xenbase:XB-GENE-961445
See related: Ensembl:ENSXETG00000013598
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: kcm1; mcak; XKCM1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	4	NC_030680.2 (91005482..91038126, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	4	NC_030680.1 (72551349..72599240)

Chromosome 4 - NC_030680.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Alteration of MCAK conformation by the point mutation E715A/E716A in the far C-terminus increased MCAK targeting to the poles and reduced MT lifetimes, which induced spindles with unfocused poles.
Title: The far C-terminus of MCAK regulates its conformation and spindle pole focusing.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables cytoskeletal motor activity	IEA Inferred from Electronic Annotation more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule motor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chromosome segregation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within microtubule-based movement	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: kinesin-like protein KIF2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006855.1 → NP_001006856.1 kinesin-like protein KIF2C

See identical proteins and their annotated locations for NP_001006856.1

Status: PROVISIONAL

Source sequence(s)

BC076961

UniProtKB/TrEMBL

A0A6I8S3Y4, F6VPJ1, Q6DEY2

Related

ENSXETP00000029801.5, ENSXETT00000029801.5

Conserved Domains (1) summary

cd01367
Location:263 → 591

KISc_KIF2_like; Kinesin motor domain, KIF2-like group

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

91005482..91038126 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_031900011.1 → XP_031755871.1 kinesin-like protein KIF2C isoform X1

UniProtKB/TrEMBL

A0A6I8RIR5, A0A8J1JGT3

Related

ENSXETP00000084765.2, ENSXETT00000091529.2

Conserved Domains (1) summary

cd01367
Location:248 → 576

KISc_KIF2_like; Kinesin motor domain, KIF2-like group