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MOS MOS proto-oncogene, serine/threonine kinase [ Bos taurus (domestic cattle) ]

Gene ID: 444869, updated on 17-Aug-2024

Summary

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Official Symbol
MOSprovided by VGNC
Official Full Name
MOS proto-oncogene, serine/threonine kinaseprovided by VGNC
Primary source
VGNC:VGNC:31563
See related
BGD:BT30082; Ensembl:ENSBTAG00000019145
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
C-MOS
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (23299079..23300457, complement)

Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U54 Neighboring gene ribosomal protein S20 Neighboring gene U1 spliceosomal RNA Neighboring gene PLAG1 zinc finger Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level. Gao Y, et al. Cell Physiol Biochem, 2014. PMID 25500918
  2. The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. Threadgill DW, et al. Cytogenet Cell Genet, 1990. PMID 2108842
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The present results suggest that demecolcine might contribute to the activation of the Mos/MAPK pathway and affect spindle structure
    Title: The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene serine/threonine-protein kinase mos
Names
oocyte maturation factor Mos
protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    23299079..23300457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002692654.5 → XP_002692700.1  proto-oncogene serine/threonine-protein kinase mos

    See identical proteins and their annotated locations for XP_002692700.1

    UniProtKB/TrEMBL
    A0AAA9SNP6, F6RCH9
    Related
    ENSBTAP00000025483.5, ENSBTAT00000025483.6
    Conserved Domains (2) summary
    smart00220
    Location:58 → 322
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13979
    Location:52 → 322
    STKc_Mos; Catalytic domain of the Serine/Threonine kinase, Oocyte maturation factor Mos
Nucleotide Protein Strain
Heading Accession and Version

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