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NPEPPSP1 NPEPPS pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 440434, updated on 5-May-2024

Summary

Official Symbol
NPEPPSP1provided by HGNC
Official Full Name
NPEPPS pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:44259
See related
Ensembl:ENSG00000291088 AllianceGenome:HGNC:44259
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NPEPPSL1
Summary
Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in esophagus (RPKM 24.1), skin (RPKM 20.6) and 25 other tissues See more
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Genomic context

Location:
17q12
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (38195740..38257249, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (39058811..39120263, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (36351796..36413256, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 6 Neighboring gene TBC1 domain family member 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:36380303-36380804 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:36399387-36399886 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:36413044-36413577 Neighboring gene uncharacterized LOC105371760 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr17:36442025-36443224 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:36452469-36453018 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:36453019-36453569 Neighboring gene mitochondrial ribosomal protein L45 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:36476257-36477193

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • Puromycin-sensitive aminopeptidase-like protein
  • aminopeptidase puromycin sensitive pseudogene

Clone Names

  • FLJ11822, FLJ57364, FLJ58835, FLJ77836

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metalloaminopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in peptide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular exosome HDA PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036750.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC244092, AC244154
    Related
    ENST00000685611.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    38195740..38257249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187614.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    2230861..2292321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    39058811..39120263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)