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MAP2 microtubule associated protein 2 [ Homo sapiens (human) ]

Gene ID: 4133, updated on 19-Jun-2019

Summary

Official Symbol
MAP2provided by HGNC
Official Full Name
microtubule associated protein 2provided by HGNC
Primary source
HGNC:HGNC:6839
See related
Ensembl:ENSG00000078018 MIM:157130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAP-2; MAP2A; MAP2B; MAP2C
Summary
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
Expression
Biased expression in brain (RPKM 82.4), thyroid (RPKM 4.7) and 1 other tissue See more
Orthologs

Genomic context

See MAP2 in Genome Data Viewer
Location:
2q34
Exon count:
21
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (209424047..209734118)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (210288733..210598842)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene MYST/Esa1-associated factor 6 pseudogene 1 Neighboring gene plakophilin 4 pseudogene 1 Neighboring gene RNA, 5S ribosomal pseudogene 118 Neighboring gene unc-80 homolog, NALCN channel complex subunit Neighboring gene snail family zinc finger 1 pseudogene 1 Neighboring gene KAT8 regulatory NSL complex subunit 1 like Neighboring gene ribulose-5-phosphate-3-epimerase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp120/MBL complex co-localizes with MAP2 and is transported along the microtubules in human primary neurons PubMed
env Ascorbate supplementation prevents the deleterious upregulation of iNOS and associated neuronal (MAP2) and astrocytic (GFAP) protein expression and structural changes caused by gp120 in human brain cell cultures PubMed
Tat tat HIV-1 Tat co-localizes with microtubule-associated protein 2 in neuronal cells PubMed
tat HIV-1 Tat downregulates expression of MAP2 in human microglia and neuroblastoma cells PubMed
retropepsin gag-pol HIV-1 protease extensively cleaves microtubule-associated proteins 1 and 2 and completely inhibits microtubule assembly PubMed

Go to the HIV-1, Human Interaction Database

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686I2148

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
dystroglycan binding IPI
Inferred from Physical Interaction
more info
PubMed 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural molecule activity NAS
Non-traceable Author Statement
more info
PubMed 
tau protein binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
axonogenesis IEA
Inferred from Electronic Annotation
more info
 
cellular response to organic substance IEA
Inferred from Electronic Annotation
more info
 
central nervous system neuron development IEP
Inferred from Expression Pattern
more info
PubMed 
dendrite development TAS
Traceable Author Statement
more info
PubMed 
dendrite morphogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
establishment of cell polarity IEA
Inferred from Electronic Annotation
more info
 
microtubule bundle formation IEA
Inferred from Electronic Annotation
more info
 
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of axon extension ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of microtubule motor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of microtubule polymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection development IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of anterograde dense core granule transport ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of anterograde synaptic vesicle transport ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cellular protein localization ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of microtubule polymerization TAS
Traceable Author Statement
more info
PubMed 
regulation of organelle transport along microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
CA3 pyramidal cell dendrite IEA
Inferred from Electronic Annotation
more info
 
apical distal dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
axon hillock ISS
Inferred from Sequence or Structural Similarity
more info
 
axon initial segment ISS
Inferred from Sequence or Structural Similarity
more info
 
basal dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
dendrite cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
dendritic branch ISS
Inferred from Sequence or Structural Similarity
more info
 
dendritic filopodium ISS
Inferred from Sequence or Structural Similarity
more info
 
dendritic growth cone ISS
Inferred from Sequence or Structural Similarity
more info
 
dendritic shaft ISS
Inferred from Sequence or Structural Similarity
more info
 
distal dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
NOT main axon ISS
Inferred from Sequence or Structural Similarity
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
microtubule associated complex TAS
Traceable Author Statement
more info
PubMed 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuronal cell body ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear periphery IEA
Inferred from Electronic Annotation
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
postsynaptic density IEA
Inferred from Electronic Annotation
more info
 
primary dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
proximal dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
proximal neuron projection ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
microtubule-associated protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052836.1 RefSeqGene

    Range
    5001..315064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001039538.1NP_001034627.1  microtubule-associated protein 2 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and includes an alternate in-frame exon, compared to variant 2, resulting in a longer protein (isoform 5), compared to isoform 2.
    Source sequence(s)
    AK055674, AK056148, AL833567, BC038857, BC066648, BX474027, BX485448, CK903071
    Consensus CDS
    CCDS33369.1
    UniProtKB/Swiss-Prot
    P11137
    UniProtKB/TrEMBL
    Q6NYC5
    Related
    ENSP00000199940.6, ENST00000199940.10
    Conserved Domains (2) summary
    pfam00418
    Location:393422
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl25751
    Location:175389
    DUF4045; Domain of unknown function (DUF4045)
  2. NM_001363910.1NP_001350839.1  microtubule-associated protein 2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in 5' UTR and includes three alternate in-frame exons compared to variant 2. It encodes a longer protein (isoform 6) compared to isoform 2. Variants 6 and 7 encode the same isoform (6).
    Source sequence(s)
    AC006385, AC019106, AC079833, AC108072
    Consensus CDS
    CCDS86916.1
    Conserved Domains (3) summary
    pfam00418
    Location:16881717
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441684
    DUF4045; Domain of unknown function (DUF4045)
  3. NM_001363911.1NP_001350840.1  microtubule-associated protein 2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) includes three alternate in-frame exons compared to variant 2. It encodes a longer protein (isoform 6) compared to isoform 2. Variants 6 and 7 encode the same isoform (6).
    Source sequence(s)
    AC006385, AC079833, AC108072
    Consensus CDS
    CCDS86916.1
    Conserved Domains (3) summary
    pfam00418
    Location:16881717
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441684
    DUF4045; Domain of unknown function (DUF4045)
  4. NM_001363913.1NP_001350842.1  microtubule-associated protein 2 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 2. Variants 2 and 8 encode the same isoform (2).
    Source sequence(s)
    AC006385, AC079833, AC108072
    Consensus CDS
    CCDS2385.1
    Conserved Domains (1) summary
    pfam00418
    Location:336365
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  5. NM_002374.3NP_002365.3  microtubule-associated protein 2 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This longest variant (1) includes three alternate in-frame exons, compared to variant 2, resulting in the longest isoform (1).
    Source sequence(s)
    AK055674, AK056148, AL833567, BC027583, BC038857, BC066648, BX431335, BX490896, CK903071, M25668, U01828, U89330
    Consensus CDS
    CCDS2384.1
    UniProtKB/Swiss-Prot
    P11137
    UniProtKB/TrEMBL
    A0A024R407, Q6NYC5
    Related
    ENSP00000353508.4, ENST00000360351.8
    Conserved Domains (3) summary
    pfam00418
    Location:16921721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14481688
    DUF4045; Domain of unknown function (DUF4045)
  6. NM_031845.2NP_114033.2  microtubule-associated protein 2 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) represents the shortest transcript and encodes the shortest isoform (2). Variants 2 and 8 encode the same isoform (2).
    Source sequence(s)
    AK055674, AK056148, AL833567, BC038857, BX490896, CK903071, U01828
    Consensus CDS
    CCDS2385.1
    UniProtKB/Swiss-Prot
    P11137
    UniProtKB/TrEMBL
    A0A024R409
    Related
    ENSP00000355290.4, ENST00000361559.8
    Conserved Domains (1) summary
    pfam00418
    Location:336365
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  7. NM_031847.2NP_114035.2  microtubule-associated protein 2 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) includes an alternate in-frame exon, compared to variant 2, resulting in a longer protein (isoform 4), compared to isoform 2.
    Source sequence(s)
    AK055674, AK056148, AL833567, BC038857, BX490896, CK903071, U01828
    UniProtKB/Swiss-Prot
    P11137
    UniProtKB/TrEMBL
    A0A024R3Y8
    Conserved Domains (2) summary
    pfam00418
    Location:336365
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl26464
    Location:176306
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    209424047..209734118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024452891.1XP_024308659.1  microtubule-associated protein 2 isoform X1

    Conserved Domains (3) summary
    pfam00418
    Location:17491778
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15311745
    DUF4045; Domain of unknown function (DUF4045)
  2. XM_024452896.1XP_024308664.1  microtubule-associated protein 2 isoform X5

    Conserved Domains (3) summary
    pfam00418
    Location:16921721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14481688
    DUF4045; Domain of unknown function (DUF4045)
  3. XM_024452900.1XP_024308668.1  microtubule-associated protein 2 isoform X9

    Conserved Domains (3) summary
    pfam00418
    Location:16921721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14481688
    DUF4045; Domain of unknown function (DUF4045)
  4. XM_024452901.1XP_024308669.1  microtubule-associated protein 2 isoform X10

    Conserved Domains (3) summary
    pfam00418
    Location:16911720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14071687
    DUF4045; Domain of unknown function (DUF4045)
  5. XM_024452894.1XP_024308662.1  microtubule-associated protein 2 isoform X3

    Conserved Domains (3) summary
    pfam00418
    Location:17451774
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15271741
    DUF4045; Domain of unknown function (DUF4045)
  6. XM_024452897.1XP_024308665.1  microtubule-associated protein 2 isoform X6

    Conserved Domains (3) summary
    pfam00418
    Location:16881717
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441684
    DUF4045; Domain of unknown function (DUF4045)
  7. XM_017004116.2XP_016859605.1  microtubule-associated protein 2 isoform X7

  8. XM_024452906.1XP_024308674.1  microtubule-associated protein 2 isoform X15

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14031683
    DUF4045; Domain of unknown function (DUF4045)
  9. XM_024452905.1XP_024308673.1  microtubule-associated protein 2 isoform X14

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441683
    DUF4045; Domain of unknown function (DUF4045)
  10. XM_024452910.1XP_024308678.1  microtubule-associated protein 2 isoform X25

    Conserved Domains (2) summary
    pfam00418
    Location:336365
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl26464
    Location:176306
    Atrophin-1; Atrophin-1 family
  11. XM_024452911.1XP_024308679.1  microtubule-associated protein 2 isoform X26

    Conserved Domains (1) summary
    pfam00418
    Location:336365
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  12. XM_011511195.2XP_011509497.1  microtubule-associated protein 2 isoform X2

    Conserved Domains (2) summary
    pfam00418
    Location:17481777
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3761504
    MAP2_projctn; MAP2/Tau projection domain
  13. XM_024452902.1XP_024308670.1  microtubule-associated protein 2 isoform X11

    Conserved Domains (3) summary
    pfam00418
    Location:16911720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3761504
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14471687
    DUF4045; Domain of unknown function (DUF4045)
  14. XM_024452895.1XP_024308663.1  microtubule-associated protein 2 isoform X4

    Conserved Domains (3) summary
    pfam00418
    Location:17441773
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15261740
    DUF4045; Domain of unknown function (DUF4045)
  15. XM_024452899.1XP_024308667.1  microtubule-associated protein 2 isoform X8

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14431683
    DUF4045; Domain of unknown function (DUF4045)
  16. XM_024452907.1XP_024308675.1  microtubule-associated protein 2 isoform X16

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14431683
    DUF4045; Domain of unknown function (DUF4045)
  17. XM_017004128.2XP_016859617.1  microtubule-associated protein 2 isoform X17

  18. XM_017004129.2XP_016859618.1  microtubule-associated protein 2 isoform X18

  19. XM_024452893.1XP_024308661.1  microtubule-associated protein 2 isoform X1

    Conserved Domains (3) summary
    pfam00418
    Location:17491778
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15311745
    DUF4045; Domain of unknown function (DUF4045)
  20. XM_017004118.2XP_016859607.1  microtubule-associated protein 2 isoform X9

    UniProtKB/Swiss-Prot
    P11137
    UniProtKB/TrEMBL
    A0A024R407
    Conserved Domains (3) summary
    pfam00418
    Location:16921721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14481688
    DUF4045; Domain of unknown function (DUF4045)
  21. XM_017004121.2XP_016859610.1  microtubule-associated protein 2 isoform X10

    Conserved Domains (3) summary
    pfam00418
    Location:16911720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14071687
    DUF4045; Domain of unknown function (DUF4045)
  22. XM_017004124.2XP_016859613.1  microtubule-associated protein 2 isoform X13

    UniProtKB/Swiss-Prot
    P11137
    Related
    ENSP00000392164.1, ENST00000447185.5
    Conserved Domains (3) summary
    pfam00418
    Location:16881717
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441684
    DUF4045; Domain of unknown function (DUF4045)
  23. XM_017004138.2XP_016859627.1  microtubule-associated protein 2 isoform X24

    UniProtKB/Swiss-Prot
    P11137
    Conserved Domains (2) summary
    pfam00418
    Location:393422
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl25751
    Location:175389
    DUF4045; Domain of unknown function (DUF4045)
  24. XM_017004122.2XP_016859611.1  microtubule-associated protein 2 isoform X11

    Conserved Domains (3) summary
    pfam00418
    Location:16911720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3761504
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14471687
    DUF4045; Domain of unknown function (DUF4045)
  25. XM_017004113.2XP_016859602.1  microtubule-associated protein 2 isoform X4

    Conserved Domains (3) summary
    pfam00418
    Location:17441773
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15261740
    DUF4045; Domain of unknown function (DUF4045)
  26. XM_017004112.2XP_016859601.1  microtubule-associated protein 2 isoform X1

    Conserved Domains (3) summary
    pfam00418
    Location:17491778
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15311745
    DUF4045; Domain of unknown function (DUF4045)
  27. XM_017004114.2XP_016859603.1  microtubule-associated protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A024R3Z1
    Conserved Domains (3) summary
    pfam00418
    Location:16921721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3771505
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14481688
    DUF4045; Domain of unknown function (DUF4045)
  28. XM_017004119.2XP_016859608.1  microtubule-associated protein 2 isoform X12

  29. XM_011511196.3XP_011509498.1  microtubule-associated protein 2 isoform X3

    Conserved Domains (3) summary
    pfam00418
    Location:17451774
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15271741
    DUF4045; Domain of unknown function (DUF4045)
  30. XM_017004126.2XP_016859615.1  microtubule-associated protein 2 isoform X15

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731501
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14031683
    DUF4045; Domain of unknown function (DUF4045)
  31. XM_017004125.2XP_016859614.1  microtubule-associated protein 2 isoform X14

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3731500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14441683
    DUF4045; Domain of unknown function (DUF4045)
  32. XM_017004120.2XP_016859609.1  microtubule-associated protein 2 isoform X11

    Conserved Domains (3) summary
    pfam00418
    Location:16911720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3761504
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14471687
    DUF4045; Domain of unknown function (DUF4045)
  33. XM_011511197.3XP_011509499.1  microtubule-associated protein 2 isoform X4

    Conserved Domains (3) summary
    pfam00418
    Location:17441773
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:15261740
    DUF4045; Domain of unknown function (DUF4045)
  34. XM_017004127.2XP_016859616.1  microtubule-associated protein 2 isoform X16

    Conserved Domains (3) summary
    pfam00418
    Location:16871716
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:3721500
    MAP2_projctn; MAP2/Tau projection domain
    cl25751
    Location:14431683
    DUF4045; Domain of unknown function (DUF4045)
  35. XM_017004130.1XP_016859619.1  microtubule-associated protein 2 isoform X19

    Conserved Domains (2) summary
    pfam00418
    Location:15911620
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:2191347
    MAP2_projctn; MAP2/Tau projection domain
  36. XM_005246565.1XP_005246622.1  microtubule-associated protein 2 isoform X19

    Conserved Domains (2) summary
    pfam00418
    Location:15911620
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:2191347
    MAP2_projctn; MAP2/Tau projection domain
  37. XM_017004131.1XP_016859620.1  microtubule-associated protein 2 isoform X20

  38. XM_017004133.1XP_016859622.1  microtubule-associated protein 2 isoform X21

  39. XM_017004136.1XP_016859625.1  microtubule-associated protein 2 isoform X22

  40. XM_005246566.1XP_005246623.1  microtubule-associated protein 2 isoform X19

    Conserved Domains (2) summary
    pfam00418
    Location:15911620
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:2191347
    MAP2_projctn; MAP2/Tau projection domain
  41. XM_017004132.1XP_016859621.1  microtubule-associated protein 2 isoform X20

  42. XM_017004134.1XP_016859623.1  microtubule-associated protein 2 isoform X21

  43. XM_017004137.1XP_016859626.1  microtubule-associated protein 2 isoform X23

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_031846.2: Suppressed sequence

    Description
    NM_031846.2: This RefSeq was permanently suppressed because currently there is insufficient support for the exon combination represented in this transcript.
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