FGG fibrinogen gamma chain [Sus scrofa (pig)] - Gene

Summary

Official Symbol: FGGprovided by VGNC
Official Full Name: fibrinogen gamma chainprovided by VGNC
Primary source: VGNC:VGNC:88122
See related: Ensembl:ENSSSCG00000024314
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: fibrinogen
Expression: Biased expression in liver (RPKM 3283.7) and mixtures (RPKM 1174.3) See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	8	NC_010450.4 (74553040..74562151)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	8	NC_010450.3 (78850804..78859881)

Chromosome 8 - NC_010450.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
Title: Fibrinogen availability and coagulation function after hemorrhage and resuscitation in pigs.

Submit: New GeneRIF Correction

General gene information

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Markers

FGG-1 (e-PCR)
- UniSTS:253977

FGG (e-PCR), detects polymorphism
- UniSTS:253977

FGG (e-PCR), detects polymorphism
- UniSTS:266088

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in blood coagulation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein polymerization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of fibrinogen complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: fibrinogen gamma chain

Names: fibrinogen gamma polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001244524.1 → NP_001231453.1 fibrinogen gamma chain precursor

See identical proteins and their annotated locations for NP_001231453.1

Status: VALIDATED

Source sequence(s)

BM659162, BP445062, EW346558, FD602664, FD603759

UniProtKB/TrEMBL

A0A4X1SSS2, A0A8D1F8J7, A0A8D1I1I0

Related

ENSSSCP00000068731.2, ENSSSCT00000069628.2

Conserved Domains (2) summary

pfam08702
Location:32 → 173

Fib_alpha; Fibrinogen alpha/beta chain family

cl00085
Location:176 → 416

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010450.4 Reference Sscrofa11.1 Primary Assembly

Range

74553040..74562151

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005666793.2 → XP_005666850.1 fibrinogen gamma chain isoform X1

See identical proteins and their annotated locations for XP_005666850.1

UniProtKB/TrEMBL

A0A8D0SAB4, A0A8D1U5L7, F1RX35, I3LJW2

Related

ENSSSCP00000024374.3, ENSSSCT00000026223.4

Conserved Domains (2) summary

pfam08702
Location:32 → 173

Fib_alpha; Fibrinogen alpha/beta chain family

cl00085
Location:176 → 416

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...