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ZNF324B zinc finger protein 324B [ Homo sapiens (human) ]

Gene ID: 388569, updated on 5-Mar-2024

Summary

Official Symbol
ZNF324Bprovided by HGNC
Official Full Name
zinc finger protein 324Bprovided by HGNC
Primary source
HGNC:HGNC:33107
See related
Ensembl:ENSG00000249471 AllianceGenome:HGNC:33107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen (RPKM 1.5), kidney (RPKM 1.4) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF324B in Genome Data Viewer
Location:
19q13.43
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (58418396..58457833)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (61514353..61553798)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58962989..58969200)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15194 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15195 Neighboring gene long intergenic non-protein coding RNA 2560 Neighboring gene ZNF584 divergent transcript Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58919203-58919848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11082 Neighboring gene zinc finger protein 584 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58951186-58951696 Neighboring gene zinc finger protein 132 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58952208-58952717 Neighboring gene ZNF132 divergent transcript Neighboring gene zinc finger protein 250 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr19:58962695-58963021 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58978178-58978794 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:58978795-58979409 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15199 Neighboring gene zinc finger protein 324 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15200 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15201 Neighboring gene Sharpr-MPRA regulatory region 9894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15203 Neighboring gene uncharacterized LOC112268251 Neighboring gene zinc finger protein 446 Neighboring gene RNA, U6 small nuclear 1337, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • FLJ45850

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207395.3NP_997278.2  zinc finger protein 324B

    See identical proteins and their annotated locations for NP_997278.2

    Status: VALIDATED

    Source sequence(s)
    AC012313, AK127750, BC140881, BM714371
    Consensus CDS
    CCDS33138.1
    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
    Related
    ENSP00000337473.3, ENST00000336614.9
    Conserved Domains (3) summary
    smart00349
    Location:161
    KRAB; krueppel associated box
    COG5048
    Location:268499
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    58418396..58457833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438807.1XP_047294763.1  zinc finger protein 324B isoform X2

  2. XM_047438806.1XP_047294762.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  3. XM_005258918.5XP_005258975.1  zinc finger protein 324B isoform X1

    See identical proteins and their annotated locations for XP_005258975.1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
    Conserved Domains (3) summary
    smart00349
    Location:161
    KRAB; krueppel associated box
    COG5048
    Location:268499
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_005258915.5XP_005258972.1  zinc finger protein 324B isoform X1

    See identical proteins and their annotated locations for XP_005258972.1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
    Related
    ENSP00000438930.1, ENST00000545523.5
    Conserved Domains (3) summary
    smart00349
    Location:161
    KRAB; krueppel associated box
    COG5048
    Location:268499
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_047438808.1XP_047294764.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  6. XM_047438809.1XP_047294765.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    61514353..61553798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054320976.1XP_054176951.1  zinc finger protein 324B isoform X2

  2. XM_054320975.1XP_054176950.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  3. XM_054320974.1XP_054176949.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  4. XM_054320979.1XP_054176954.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  5. XM_054320977.1XP_054176952.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42
  6. XM_054320978.1XP_054176953.1  zinc finger protein 324B isoform X1

    UniProtKB/Swiss-Prot
    B2RTZ6, Q6AW86, Q6ZMX8, Q6ZS42