U.S. flag

An official website of the United States government


Send to:

Choose Destination

Rnf225 ring finger protein 225 [ Mus musculus (house mouse) ]

Gene ID: 381845, updated on 5-Mar-2024


Official Symbol
Rnf225provided by MGI
Official Full Name
ring finger protein 225provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000033967 AllianceGenome:MGI:1924198
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in genitourinary system; gut; and skin. Orthologous to human RNF225 (ring finger protein 225). [provided by Alliance of Genome Resources, Apr 2022]
Biased expression in stomach adult (RPKM 6.5), lung adult (RPKM 2.1) and 13 other tissues See more
Try the new Gene table
Try the new Transcript table

Genomic context

See Rnf225 in Genome Data Viewer
7 A1; 7 7.69 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (12661343..12664999)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (12927416..12931072)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr7:13482923-13483223 Neighboring gene zinc finger and SCAN domain containing 22 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:13495643-13495826 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:13507414-13507597 Neighboring gene ribosomal protein S5 Neighboring gene predicted gene, 26325 Neighboring gene RIKEN cDNA 1810019N24 gene Neighboring gene STARR-seq mESC enhancer starr_18063 Neighboring gene predicted gene 29638 Neighboring gene zinc finger protein 324

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029809.2NP_084085.1  RING finger protein 225

    See identical proteins and their annotated locations for NP_084085.1

    Status: VALIDATED

    Source sequence(s)
    AK028523, BF460478
    Consensus CDS
    ENSMUSP00000042816.5, ENSMUST00000045870.5
    Conserved Domains (1) summary
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000073.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)