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RGSL1 regulator of G protein signaling like 1 [ Homo sapiens (human) ]

Gene ID: 353299, updated on 22-Sep-2022

Summary

Official Symbol
RGSL1provided by HGNC
Official Full Name
regulator of G protein signaling like 1provided by HGNC
Primary source
HGNC:HGNC:18636
See related
Ensembl:ENSG00000121446 MIM:611012; AllianceGenome:HGNC:18636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RGSL; RGSL2
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 3.0) See more
Orthologs
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Genomic context

See RGSL1 in Genome Data Viewer
Location:
1q25.3
Exon count:
31
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (182447877..182560597)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (181809719..181920071)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (182419281..182529732)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 272 Neighboring gene transmembrane epididymal protein 2, pseudogene Neighboring gene ribonuclease L Neighboring gene regulator of G protein signaling 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp434E169

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
regulator of G-protein signaling protein-like
Names
regulator of G-protein signaling like 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001137669.2NP_001131141.1  regulator of G-protein signaling protein-like isoform 1

    See identical proteins and their annotated locations for NP_001131141.1

    Status: VALIDATED

    Source sequence(s)
    AF508902, BC142944
    Consensus CDS
    CCDS58049.1
    UniProtKB/Swiss-Prot
    A5PLK6, Q9H084
    Related
    ENSP00000457748.1, ENST00000294854.13
    Conserved Domains (2) summary
    cd08728
    Location:650829
    RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
    cl02565
    Location:876980
    RGS; Regulator of G protein signaling (RGS) domain superfamily
  2. NM_001366934.1NP_001353863.1  regulator of G-protein signaling protein-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL138776, AL139344

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    182447877..182560597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001193.3XP_016856682.1  regulator of G-protein signaling protein-like isoform X2

  2. XM_017001191.1XP_016856680.1  regulator of G-protein signaling protein-like isoform X2

  3. XM_017001192.3XP_016856681.1  regulator of G-protein signaling protein-like isoform X2

  4. XM_017001189.2XP_016856678.1  regulator of G-protein signaling protein-like isoform X2

  5. XM_017001188.2XP_016856677.1  regulator of G-protein signaling protein-like isoform X1

    Conserved Domains (2) summary
    cd08728
    Location:685864
    RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
    cl02565
    Location:9111015
    RGS; Regulator of G protein signaling (RGS) domain superfamily
  6. XM_047419638.1XP_047275594.1  regulator of G-protein signaling protein-like isoform X5

    UniProtKB/TrEMBL
    H3BU64
    Related
    ENSP00000457491.1, ENST00000443996.6
  7. XM_011509494.3XP_011507796.1  regulator of G-protein signaling protein-like isoform X3

    See identical proteins and their annotated locations for XP_011507796.1

    Conserved Domains (2) summary
    cd08728
    Location:685864
    RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
    cl02565
    Location:9111011
    RGS; Regulator of G protein signaling (RGS) domain superfamily
  8. XM_011509500.2XP_011507802.1  regulator of G-protein signaling protein-like isoform X6

    Conserved Domains (1) summary
    cl02565
    Location:685782
    RGS; Regulator of G protein signaling (RGS) domain superfamily
  9. XM_017001190.2XP_016856679.1  regulator of G-protein signaling protein-like isoform X2

  10. XM_047419632.1XP_047275588.1  regulator of G-protein signaling protein-like isoform X4

  11. XM_017001196.1XP_016856685.1  regulator of G-protein signaling protein-like isoform X7

    UniProtKB/Swiss-Prot
    A5PLK6
    Conserved Domains (2) summary
    cd08728
    Location:173352
    RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
    cl02565
    Location:399503
    RGS; Regulator of G protein signaling (RGS) domain superfamily
  12. XM_047419640.1XP_047275596.1  regulator of G-protein signaling protein-like isoform X7

  13. XM_047419642.1XP_047275598.1  regulator of G-protein signaling protein-like isoform X8

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    181809719..181920071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_032267.2: Suppressed sequence

    Description
    NM_032267.2: This RefSeq was permanently suppressed because it contains a partial CDS and the complete transcript would be a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_181572.2: Suppressed sequence

    Description
    NM_181572.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.