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ZNF860 zinc finger protein 860 [ Homo sapiens (human) ]

Gene ID: 344787, updated on 10-Oct-2019

Summary

Official Symbol
ZNF860provided by HGNC
Official Full Name
zinc finger protein 860provided by HGNC
Primary source
HGNC:HGNC:34513
See related
Ensembl:ENSG00000197385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in lymph node (RPKM 1.1), prostate (RPKM 0.9) and 21 other tissues See more
Orthologs

Genomic context

See ZNF860 in Genome Data Viewer
Location:
3p23-p22.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (31981750..32005112)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (32023266..32033228)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein like 10 Neighboring gene OSBPL10 antisense RNA 1 Neighboring gene zinc finger protein 587 pseudogene 1 Neighboring gene ribosomal protein L21 pseudogene 40 Neighboring gene nucleolar protein interacting with the FHA domain of MKI67 pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.
NHGRI GWA Catalog

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ60236

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001137674.3NP_001131146.2  zinc finger protein 860

    See identical proteins and their annotated locations for NP_001131146.2

    Status: VALIDATED

    Source sequence(s)
    AC108485, AK294003, BQ268755
    Consensus CDS
    CCDS46784.1
    UniProtKB/Swiss-Prot
    A6NHJ4
    Related
    ENSP00000373274.3, ENST00000360311.5
    Conserved Domains (5) summary
    smart00349
    Location:2464
    KRAB; krueppel associated box
    COG5048
    Location:284617
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288308
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2463
    KRAB; KRAB box
    pfam13465
    Location:328353
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    31981750..32005112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017006299.1XP_016861788.1  zinc finger protein 860 isoform X1

    UniProtKB/Swiss-Prot
    A6NHJ4
    Conserved Domains (5) summary
    smart00349
    Location:2464
    KRAB; krueppel associated box
    COG5048
    Location:284617
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288308
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2463
    KRAB; KRAB box
    pfam13465
    Location:328353
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_001740138.1 RNA Sequence

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