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ZNF284 zinc finger protein 284 [ Homo sapiens (human) ]

Gene ID: 342909, updated on 13-May-2022

Summary

Official Symbol
ZNF284provided by HGNC
Official Full Name
zinc finger protein 284provided by HGNC
Primary source
HGNC:HGNC:13078
See related
Ensembl:ENSG00000186026 AllianceGenome:HGNC:13078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF284L
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in skin (RPKM 1.1), spleen (RPKM 0.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF284 in Genome Data Viewer
Location:
19q13.31
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (44072159..44089613)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (46895067..46912496)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44576312..44593766)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 222 Neighboring gene zinc finger protein 223 Neighboring gene RNA, U6 small nuclear 902, pseudogene Neighboring gene zinc finger protein 224 Neighboring gene ZNF225 and ZNF224 antisense RNA 1 Neighboring gene zinc finger protein 225

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp781F1775

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037813.4NP_001032902.1  zinc finger protein 284

    See identical proteins and their annotated locations for NP_001032902.1

    Status: VALIDATED

    Source sequence(s)
    AC084219, AY458845, BM989725
    Consensus CDS
    CCDS46099.1
    UniProtKB/Swiss-Prot
    Q2VY69
    Related
    ENSP00000411032.2, ENST00000421176.4
    Conserved Domains (3) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:209554
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:205225
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    44072159..44089613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451486.2XP_024307254.1  zinc finger protein 284 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:209554
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:205225
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011526907.4XP_011525209.1  zinc finger protein 284 isoform X1

    See identical proteins and their annotated locations for XP_011525209.1

    UniProtKB/Swiss-Prot
    Q2VY69
    Conserved Domains (3) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:209554
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:205225
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011526908.4XP_011525210.1  zinc finger protein 284 isoform X1

    See identical proteins and their annotated locations for XP_011525210.1

    UniProtKB/Swiss-Prot
    Q2VY69
    Conserved Domains (3) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:209554
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:205225
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    46895067..46912496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)