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SNAI3 snail family transcriptional repressor 3 [ Homo sapiens (human) ]

Gene ID: 333929, updated on 8-Jul-2018
Official Symbol
SNAI3provided by HGNC
Official Full Name
snail family transcriptional repressor 3provided by HGNC
Primary source
HGNC:HGNC:18411
See related
Ensembl:ENSG00000185669 MIM:612741; Vega:OTTHUMG00000173243
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SMUC; SNAIL3; ZNF293; Zfp293
Summary
SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]
Expression
Broad expression in lymph node (RPKM 1.8), spleen (RPKM 1.7) and 25 other tissues See more
Orthologs
See SNAI3 in Genome Data Viewer
Location:
16q24.2
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 16 NC_000016.10 (88677682..88686474, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (88744090..88753192, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene cytochrome b-245 alpha chain Neighboring gene SNAI3 antisense RNA 1 Neighboring gene mevalonate diphosphate decarboxylase Neighboring gene ring finger protein 166 Neighboring gene cytosolic thiouridylase subunit 2 Neighboring gene piezo type mechanosensitive ion channel component 1

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC129606

Gene Ontology Provided by GOA

Process Evidence Code Pubs
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
zinc finger protein SNAI3
Names
protein snail homolog 3
snail family zinc finger 3
snail homolog 3
zinc finger protein 293

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178310.3NP_840101.1  zinc finger protein SNAI3

    See identical proteins and their annotated locations for NP_840101.1

    Status: VALIDATED

    Source sequence(s)
    AC138028, BC107058
    Consensus CDS
    CCDS32505.1
    UniProtKB/Swiss-Prot
    Q3KNW1
    Related
    ENSP00000327968.5, OTTHUMP00000250258, ENST00000332281.5, OTTHUMT00000422582
    Conserved Domains (3) summary
    COG5048
    Location:206278
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:154174
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p12 Primary Assembly

    Range
    88677682..88686474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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