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H4c16 H4 histone 16 [ Mus musculus (house mouse) ]

Gene ID: 320332, updated on 7-May-2024


Official Symbol
H4c16provided by MGI
Official Full Name
H4 histone 16provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000096010 AllianceGenome:MGI:2448443
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H4c1; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4-16; H4c11; H4c12; H4c14; H4f16; Hist4h4; B130044J01Rik
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. [provided by RefSeq, Aug 2015]
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Genomic context

See H4c16 in Genome Data Viewer
6 G1; 6 66.72 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (136780991..136781429, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (136803993..136804431, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene guanylate cyclase 2c Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:136692382-136692565 Neighboring gene STARR-seq mESC enhancer starr_17608 Neighboring gene predicted gene, 40411 Neighboring gene H2J.A histone Neighboring gene STARR-seq mESC enhancer starr_17611 Neighboring gene WW domain binding protein 11 Neighboring gene cDNA sequence BC049715

Genomic regions, transcripts, and products


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of chromatin ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
part_of CENP-A containing nucleosome ISO
Inferred from Sequence Orthology
more info
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
histone H4
histone 4, H4
histone cluster 4, H4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175652.3NP_783583.1  histone H4

    See identical proteins and their annotated locations for NP_783583.1

    Status: REVIEWED

    Source sequence(s)
    Consensus CDS
    A0AUM5, A4FUP8, A4QMY0, P62806, Q0VDL9, Q2M2Q5, Q5T006, Q6PDS7, Q811M0, Q9D0C9, Q9D6Q8
    ENSMUSP00000136357.2, ENSMUST00000179285.3
    Conserved Domains (1) summary
    PLN00035; histone H4; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000072.7 Reference GRCm39 C57BL/6J

    136780991..136781429 complement
    GenBank, FASTA, Sequence Viewer (Graphics)