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Togaram2 TOG array regulator of axonemal microtubules 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313892, updated on 17-Aug-2024

Summary

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Official Symbol
Togaram2provided by RGD
Official Full Name
TOG array regulator of axonemal microtubules 2provided by RGD
Primary source
RGD:1310677
See related
EnsemblRapid:ENSRNOG00000026344 AllianceGenome:RGD:1310677
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam179a; RGD1310677
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle assembly. Predicted to be active in cilium and microtubule cytoskeleton. Orthologous to human TOGARAM2 (TOG array regulator of axonemal microtubules 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 11.4), Lung (RPKM 8.7) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Togaram2 in Genome Data Viewer
Location:
6q14
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (29491183..29549004, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (23770979..23828884, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (23358762..23416386, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene histidine-rich glycoprotein-like Neighboring gene CAP-GLY domain containing linker protein family, member 4 Neighboring gene photoreceptor cilium actin regulator Neighboring gene WD repeat domain 43 Neighboring gene small nucleolar RNA, C/D box 53B Neighboring gene small nucleolar RNA, C/D box 53

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of supramolecular fiber organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
TOG array regulator of axonemal microtubules protein 2
Names
family with sequence similarity 179, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    29491183..29549004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594409.3 → XP_017449898.2  TOG array regulator of axonemal microtubules protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I6GFQ3
    Related
    ENSRNOP00000109268.1, ENSRNOT00000170675.1
    Conserved Domains (2) summary
    PLN03209
    Location:151 → 442
    PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
    pfam12348
    Location:627 → 795
    CLASP_N; CLASP N terminal

  2. XM_017594408.3 → XP_017449897.2  TOG array regulator of axonemal microtubules protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GFQ3
    Conserved Domains (2) summary
    PLN03209
    Location:196 → 475
    PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
    pfam12348
    Location:660 → 828
    CLASP_N; CLASP N terminal

  3. XM_017594410.3 → XP_017449899.1  TOG array regulator of axonemal microtubules protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8I6GFQ3, D4A1L0
    Related
    ENSRNOP00000038699.5, ENSRNOT00000036374.5

  4. XM_002729599.7 → XP_002729645.5  TOG array regulator of axonemal microtubules protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GFQ3
    Related
    ENSRNOP00000088008.2, ENSRNOT00000093836.2
    Conserved Domains (2) summary
    PLN03209
    Location:196 → 475
    PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
    pfam12348
    Location:660 → 828
    CLASP_N; CLASP N terminal

  5. XM_063262603.1 → XP_063118673.1  TOG array regulator of axonemal microtubules protein 2 isoform X6

  6. XM_063262602.1 → XP_063118672.1  TOG array regulator of axonemal microtubules protein 2 isoform X5

Nucleotide Protein Strain
Heading Accession and Version

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