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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_047078.1 RefSeqGene
- Range
-
5975..329174
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000827.4 → NP_000818.2 glutamate receptor 1 isoform 1 precursor
See identical proteins and their annotated locations for NP_000818.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1.
- Source sequence(s)
-
AB209094, AK310189, AL120214, DC335107, M81886, X58633
- Consensus CDS
-
CCDS4322.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000285900.4, ENST00000285900.10
- Conserved Domains (2) summary
-
- cd13729
Location:406 → 787
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cd06390
Location:26 → 392
- PBP1_iGluR_AMPA_GluR1; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR1 subunit of the AMPA receptor
-
NM_001114183.2 → NP_001107655.1 glutamate receptor 1 isoform 2 precursor
See identical proteins and their annotated locations for NP_001107655.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has a different coding exon in the 3' region, as compared to variant 1. The resulting isoform (2) is the same length but has a different internal segment, as compared to isoform 1.
- Source sequence(s)
-
AB209094, AL120214, DC335107, M64752
- Consensus CDS
-
CCDS47318.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000339343.5, ENST00000340592.9
- Conserved Domains (2) summary
-
- cd13729
Location:406 → 787
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cd06390
Location:26 → 392
- PBP1_iGluR_AMPA_GluR1; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR1 subunit of the AMPA receptor
-
NM_001258019.2 → NP_001244948.1 glutamate receptor 1 isoform 3 precursor
See identical proteins and their annotated locations for NP_001244948.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.
- Source sequence(s)
-
AB209094, AK295827, AL120214
- Consensus CDS
-
CCDS58986.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000427920.1, ENST00000518142.5
- Conserved Domains (2) summary
-
- cd13729
Location:326 → 707
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cl10011
Location:26 → 312
- Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
-
NM_001258020.2 → NP_001244949.1 glutamate receptor 1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and has an alternate in-frame exon in place of another exon of the same size. The resulting isoform (4) is shorter at the N-terminus and has a different sequence (but same length) segment in the C-terminus compared to isoform 1.
- Source sequence(s)
-
AB209094, AL120214, DC335107
- UniProtKB/TrEMBL
-
Q59GL5
- Conserved Domains (4) summary
-
- cd13729
Location:311 → 692
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- pfam00060
Location:443 → 722
- Lig_chan; Ligand-gated ion channel
- pfam01094
Location:1 → 277
- ANF_receptor; Receptor family ligand binding region
- cl10011
Location:1 → 294
- Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
-
NM_001258021.2 → NP_001244950.1 glutamate receptor 1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) has an alternate exon in place of the 5'-most exon of variant 1. The resulting isoform (5) has a longer and distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AB209094, AK295184, AK295827, AK315934, AL120214
- Consensus CDS
-
CCDS58987.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000428994.1, ENST00000518783.1
- Conserved Domains (4) summary
-
- cd06390
Location:36 → 399
- PBP1_iGluR_AMPA_GluR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR1 subunit of the AMPA receptor
- cd13729
Location:416 → 797
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- pfam00060
Location:548 → 827
- Lig_chan; Ligand-gated ion channel
- pfam01094
Location:47 → 382
- ANF_receptor; Receptor family ligand binding region
-
NM_001258022.2 → NP_001244951.1 glutamate receptor 1 isoform 6
See identical proteins and their annotated locations for NP_001244951.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) has an alternate exon in place of the 5'-most exon of variant 1 and has an alternate in-frame exon in place of another exon of the same size. The resulting isoform (6) has a longer and distinct N-terminus and has a different sequence (but same length) segment in the C-terminus compared to isoform 1.
- Source sequence(s)
-
AB209094, AK295184, AK315934, AL120214
- Consensus CDS
-
CCDS58988.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000415569.2, ENST00000448073.8
- Conserved Domains (4) summary
-
- cd06390
Location:36 → 399
- PBP1_iGluR_AMPA_GluR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR1 subunit of the AMPA receptor
- cd13729
Location:416 → 797
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- pfam00060
Location:548 → 827
- Lig_chan; Ligand-gated ion channel
- pfam01094
Location:47 → 382
- ANF_receptor; Receptor family ligand binding region
-
NM_001258023.1 → NP_001244952.1 glutamate receptor 1 isoform 7
See identical proteins and their annotated locations for NP_001244952.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) has an alternate exon in place of the 5'-most exon of variant 1. The resulting isoform (7) is shorter at the N-terminus compared to isoform 1.
- Source sequence(s)
-
AB209094, AK295039, AL120214
- Consensus CDS
-
CCDS58989.1
- UniProtKB/Swiss-Prot
-
P42261
- UniProtKB/TrEMBL
-
Q59GL5
- Related
- ENSP00000427864.2, ENST00000521843.6
- Conserved Domains (2) summary
-
- cd13729
Location:337 → 718
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cl10011
Location:1 → 323
- Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
-
NM_001364165.2 → NP_001351094.1 glutamate receptor 1 isoform 8 precursor
Status: REVIEWED
- Source sequence(s)
-
AC010613, AC091960, AC091962
- Conserved Domains (2) summary
-
- cd13729
Location:350 → 731
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cl10011
Location:26 → 336
- Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
-
NM_001364166.2 → NP_001351095.1 glutamate receptor 1 isoform 9
Status: REVIEWED
- Source sequence(s)
-
AC010613, AC091960, AC091962
- Conserved Domains (2) summary
-
- cd06390
Location:35 → 398
- PBP1_iGluR_AMPA_GluR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR1 subunit of the AMPA receptor
- cd13729
Location:415 → 796
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
-
NM_001364167.2 → NP_001351096.1 glutamate receptor 1 isoform 10
Status: REVIEWED
- Source sequence(s)
-
AC010613, AC091960, AC091962
- Conserved Domains (2) summary
-
- cd13729
Location:337 → 718
- PBP2_iGluR_AMPA_GluR1; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR1 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
- cl10011
Location:1 → 323
- Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
RNA
-
NR_047578.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) lacks an alternate 5' exon and an alternate 3' exon compared to variant 1. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is therefore thought to be non-protein coding.
- Source sequence(s)
-
AB209094, AC091960, AK294011, AL120214
-
NR_157093.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010613, AC091960, AC091962
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p13 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p13 Primary Assembly
- Range
-
153490670..153813873
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017009392.1 → XP_016864881.1 glutamate receptor 1 isoform X1