U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TRBC1 T cell receptor beta constant 1 [ Homo sapiens (human) ]

Gene ID: 28639, updated on 8-Dec-2022

Summary

Official Symbol
TRBC1provided by HGNC
Official Full Name
T cell receptor beta constant 1provided by HGNC
Primary source
HGNC:HGNC:12156
See related
Ensembl:ENSG00000211751 IMGT/GENE-DB:TRBC1; MIM:186930; AllianceGenome:HGNC:12156
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TCRB; TCRBC1; BV05S1J2.2
Summary
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be located in plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TRBC1 in Genome Data Viewer
Location:
7q34
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (142791694..142793141)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (144147412..144148859)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 (PATCHES) NW_003571040.1 (994738..996185)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene T cell receptor beta locus Neighboring gene uncharacterized LOC124901762 Neighboring gene T cell receptor beta joining 1-5 Neighboring gene T cell receptor beta joining 1-6 Neighboring gene T cell receptor beta joining 2-1 Neighboring gene T cell receptor beta diversity 2

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • V_segment translation product

Clone Names

  • MGC88817

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in T cell receptor signaling pathway NAS
Non-traceable Author Statement
more info
PubMed 
involved_in adaptive immune response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in alpha-beta T cell activation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in immune response NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
part_of alpha-beta T cell receptor complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001333.2 

    Range
    645749..647196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    142791694..142793141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187562.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    814667..816114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    144147412..144148859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)