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KIAA0825 KIAA0825 [ Homo sapiens (human) ]

Gene ID: 285600, updated on 12-Oct-2019

Summary

Official Symbol
KIAA0825provided by HGNC
Official Full Name
KIAA0825provided by HGNC
Primary source
HGNC:HGNC:28532
See related
Ensembl:ENSG00000185261 MIM:617266
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PAPA10; C5orf36
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See KIAA0825 in Genome Data Viewer
Location:
5q15
Exon count:
32
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (94150856..94618604, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (93486556..93954309, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 172 member A Neighboring gene POU domain class 5, transcription factor 2 Neighboring gene VISTA enhancer hs271 Neighboring gene uncharacterized LOC105379087 Neighboring gene uncharacterized LOC105379086 Neighboring gene FAST kinase domains 1 pseudogene Neighboring gene MT-ND5 pseudogene 12 Neighboring gene MT-CYB pseudogene 35 Neighboring gene MT-ND6 pseudogene 3 Neighboring gene SMC5-SMC6 complex localization factor 1 Neighboring gene multiple C2 and transmembrane domain containing 1 Neighboring gene ribosomal protein L7 pseudogene 18 Neighboring gene uncharacterized LOC105379085

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
POLYDACTYLY, POSTAXIAL, TYPE A10
MedGen: CN260589 OMIM: 618498 GeneReviews: Not available
not available

NHGRI GWAS Catalog

Description
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
NHGRI GWA Catalog
Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.
NHGRI GWA Catalog
Genome-wide association study of diabetic retinopathy in a Taiwanese population.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ27431, KIAA0825, MGC34713, DKFZp686F0372

General protein information

Preferred Names
uncharacterized protein KIAA0825

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145678.2NP_001139150.1  uncharacterized protein KIAA0825 isoform 1

    See identical proteins and their annotated locations for NP_001139150.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC025766, AC093311, AC104127, AC117521
    UniProtKB/Swiss-Prot
    Q8IV33
    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  2. NM_173665.3NP_775936.1  uncharacterized protein KIAA0825 isoform 2

    See identical proteins and their annotated locations for NP_775936.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an early polyA signal that omits 16 exons from the 3' end, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK308195, BC035515, BX648338
    Consensus CDS
    CCDS4070.1
    UniProtKB/Swiss-Prot
    Q8IV33
    Related
    ENSP00000331385.6, ENST00000329378.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    94150856..94618604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714588.2XP_006714651.1  uncharacterized protein KIAA0825 isoform X3

    Related
    ENSP00000424618.2, ENST00000513200.7
    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  2. XM_011543331.1XP_011541633.1  uncharacterized protein KIAA0825 isoform X4

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  3. XM_017009375.2XP_016864864.1  uncharacterized protein KIAA0825 isoform X11

    Conserved Domains (1) summary
    pfam14906
    Location:127444
    DUF4495; Domain of unknown function (DUF4495)
  4. XM_011543335.2XP_011541637.1  uncharacterized protein KIAA0825 isoform X10

    Conserved Domains (1) summary
    pfam14906
    Location:403720
    DUF4495; Domain of unknown function (DUF4495)
  5. XM_011543324.2XP_011541626.1  uncharacterized protein KIAA0825 isoform X1

    See identical proteins and their annotated locations for XP_011541626.1

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  6. XM_011543325.3XP_011541627.1  uncharacterized protein KIAA0825 isoform X1

    See identical proteins and their annotated locations for XP_011541627.1

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  7. XM_011543329.2XP_011541631.1  uncharacterized protein KIAA0825 isoform X1

    See identical proteins and their annotated locations for XP_011541631.1

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  8. XM_011543328.3XP_011541630.1  uncharacterized protein KIAA0825 isoform X1

    See identical proteins and their annotated locations for XP_011541630.1

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  9. XM_011543327.2XP_011541629.1  uncharacterized protein KIAA0825 isoform X1

    See identical proteins and their annotated locations for XP_011541629.1

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  10. XM_017009374.1XP_016864863.1  uncharacterized protein KIAA0825 isoform X9

  11. XM_011543330.2XP_011541632.1  uncharacterized protein KIAA0825 isoform X2

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  12. XM_017009373.1XP_016864862.1  uncharacterized protein KIAA0825 isoform X7

  13. XM_011543334.2XP_011541636.1  uncharacterized protein KIAA0825 isoform X6

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  14. XM_011543333.2XP_011541635.1  uncharacterized protein KIAA0825 isoform X8

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  15. XM_011543332.1XP_011541634.1  uncharacterized protein KIAA0825 isoform X5

    Conserved Domains (1) summary
    pfam14906
    Location:515832
    DUF4495; Domain of unknown function (DUF4495)
  16. XM_017009377.1XP_016864866.1  uncharacterized protein KIAA0825 isoform X12

    UniProtKB/Swiss-Prot
    Q8IV33
  17. XM_017009376.2XP_016864865.1  uncharacterized protein KIAA0825 isoform X12

    UniProtKB/Swiss-Prot
    Q8IV33

RNA

  1. XR_948246.2 RNA Sequence

  2. XR_001742053.2 RNA Sequence

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