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CCDC150 coiled-coil domain containing 150 [ Homo sapiens (human) ]

Gene ID: 284992, updated on 1-Jun-2020

Summary

Official Symbol
CCDC150provided by HGNC
Official Full Name
coiled-coil domain containing 150provided by HGNC
Primary source
HGNC:HGNC:26834
See related
Ensembl:ENSG00000144395
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 4.2), bone marrow (RPKM 0.6) and 6 other tissues See more
Orthologs

Genomic context

See CCDC150 in Genome Data Viewer
Location:
2q33.1
Exon count:
33
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (196639632..196733668)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (197504278..197597530)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 Neighboring gene uncharacterized LOC105373821 Neighboring gene uncharacterized LOC105373823 Neighboring gene uncharacterized LOC100130452 Neighboring gene general transcription factor IIIC subunit 3 Neighboring gene chromosome 2 open reading frame 66

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10202, FLJ38811, FLJ39660, MGC72171, DKFZp434P055

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
coiled-coil domain-containing protein 150

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080539.2NP_001074008.1  coiled-coil domain-containing protein 150 isoform 1

    See identical proteins and their annotated locations for NP_001074008.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC068544
    Consensus CDS
    CCDS46478.1
    UniProtKB/Swiss-Prot
    Q8NCX0
    Related
    ENSP00000373827.4, ENST00000389175.9
    Conserved Domains (2) summary
    COG1196
    Location:192929
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl19219
    Location:412507
    DUF342; Protein of unknown function (DUF342)
  2. NM_001353339.2NP_001340268.1  coiled-coil domain-containing protein 150 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence and lacks an in-frame exon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AC068544, AK096979, AK302685
    Conserved Domains (1) summary
    cl25732
    Location:2678
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_001353340.1NP_001340269.1  coiled-coil domain-containing protein 150 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and lacks an in-frame exon compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
    Source sequence(s)
    AC068544
    Conserved Domains (1) summary
    cl25732
    Location:117374
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    196639632..196733668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006712438.3XP_006712501.1  coiled-coil domain-containing protein 150 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:3281010
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl19219
    Location:412507
    DUF342; Protein of unknown function (DUF342)
  2. XM_017003863.1XP_016859352.1  coiled-coil domain-containing protein 150 isoform X4

  3. XM_017003862.1XP_016859351.1  coiled-coil domain-containing protein 150 isoform X3

  4. XM_017003861.1XP_016859350.1  coiled-coil domain-containing protein 150 isoform X2

  5. XM_017003864.1XP_016859353.1  coiled-coil domain-containing protein 150 isoform X6

  6. XM_011510985.2XP_011509287.1  coiled-coil domain-containing protein 150 isoform X5

    Conserved Domains (2) summary
    TIGR02168
    Location:225907
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl19219
    Location:309404
    DUF342; Protein of unknown function (DUF342)
  7. XM_017003865.1XP_016859354.1  coiled-coil domain-containing protein 150 isoform X7

    UniProtKB/TrEMBL
    B4DZ03
    Conserved Domains (1) summary
    cl25732
    Location:2678
    SMC_N; RecF/RecN/SMC N terminal domain
  8. XM_011510988.2XP_011509290.1  coiled-coil domain-containing protein 150 isoform X8

    Conserved Domains (2) summary
    pfam07851
    Location:352434
    TMPIT; TMPIT-like protein
    cl09914
    Location:248388
    PHA_synth_III_E; Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)
  9. XM_011510987.2XP_011509289.1  coiled-coil domain-containing protein 150 isoform X7

    See identical proteins and their annotated locations for XP_011509289.1

    UniProtKB/TrEMBL
    B4DZ03
    Conserved Domains (1) summary
    cl25732
    Location:2678
    SMC_N; RecF/RecN/SMC N terminal domain
  10. XM_017003866.1XP_016859355.1  coiled-coil domain-containing protein 150 isoform X7

    UniProtKB/TrEMBL
    B4DZ03
    Conserved Domains (1) summary
    cl25732
    Location:2678
    SMC_N; RecF/RecN/SMC N terminal domain
  11. XM_006712439.3XP_006712502.1  coiled-coil domain-containing protein 150 isoform X9

    UniProtKB/TrEMBL
    B8ZZI4
    Related
    ENSP00000387257.1, ENST00000409270.5
    Conserved Domains (2) summary
    pfam07851
    Location:334416
    TMPIT; TMPIT-like protein
    cl09914
    Location:230370
    PHA_synth_III_E; Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)

RNA

  1. XR_002959278.1 RNA Sequence

  2. XR_001738711.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_173466.1: Suppressed sequence

    Description
    NM_173466.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_173646.1: Suppressed sequence

    Description
    NM_173646.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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