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SLC25A41 solute carrier family 25 member 41 [ Homo sapiens (human) ]

Gene ID: 284427, updated on 23-Nov-2021

Summary

Official Symbol
SLC25A41provided by HGNC
Official Full Name
solute carrier family 25 member 41provided by HGNC
Primary source
HGNC:HGNC:28533
See related
Ensembl:ENSG00000181240 MIM:610822
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
APC4; SCaMC-3L
Summary
SLC25A41 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
Expression
Broad expression in testis (RPKM 3.0), brain (RPKM 0.8) and 14 other tissues See more
Orthologs
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Genomic context

See SLC25A41 in Genome Data Viewer
Location:
19p13.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (6426037..6436267, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (6426048..6433774, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene adenylate kinase isoenzyme 1-like Neighboring gene KH-type splicing regulatory protein Neighboring gene microRNA 3940 Neighboring gene solute carrier family 25 member 23 Neighboring gene DENN domain containing 1C Neighboring gene crumbs cell polarity complex component 3 Neighboring gene Sharpr-MPRA regulatory region 5032

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ40442, MGC34725

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ADP transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables ATP transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in ADP transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in ATP transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in mitochondrial ADP transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in mitochondrial ATP transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
mitochondrial carrier protein SCaMC-3L
Names
SCaMC-3-like
mitochondrial ATP-Mg/Pi carrier protein SLC25A41
small calcium-binding mitochondrial carrier protein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321298.2NP_001308227.1  mitochondrial carrier protein SCaMC-3L isoform b

    Status: VALIDATED

    Source sequence(s)
    AC011539, AK097761, BC031671
    UniProtKB/Swiss-Prot
    Q8N5S1
    Conserved Domains (1) summary
    pfam00153
    Location:44136
    Mito_carr; Mitochondrial carrier protein
  2. NM_173637.4NP_775908.2  mitochondrial carrier protein SCaMC-3L isoform a

    See identical proteins and their annotated locations for NP_775908.2

    Status: VALIDATED

    Source sequence(s)
    AC011539, AK097761, BC031671
    Consensus CDS
    CCDS45937.1
    UniProtKB/Swiss-Prot
    Q8N5S1
    Related
    ENSP00000322649.5, ENST00000321510.7
    Conserved Domains (2) summary
    PTZ00169
    Location:87368
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:182274
    Mito_carr; Mitochondrial carrier protein

RNA

  1. NR_135612.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BC031671
    Related
    ENST00000458275.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    6426037..6436267 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527926.1XP_011526228.1  mitochondrial carrier protein SCaMC-3L isoform X1

    Conserved Domains (2) summary
    PTZ00169
    Location:23304
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:118210
    Mito_carr; Mitochondrial carrier protein
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