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ZIK1 zinc finger protein interacting with K protein 1 [ Homo sapiens (human) ]

Gene ID: 284307, updated on 23-Nov-2021

Summary

Official Symbol
ZIK1provided by HGNC
Official Full Name
zinc finger protein interacting with K protein 1provided by HGNC
Primary source
HGNC:HGNC:33104
See related
Ensembl:ENSG00000171649
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF762
Expression
Broad expression in thyroid (RPKM 2.1), testis (RPKM 1.9) and 24 other tissues See more
Orthologs
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Genomic context

See ZIK1 in Genome Data Viewer
Location:
19q13.43
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57583642..57593890)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58095513..58105258)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 550 Neighboring gene zinc finger protein 416 Neighboring gene zinc finger protein 530 Neighboring gene zinc finger protein 134

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119699, MGC119700, MGC119701

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein interacting with ribonucleoprotein K
Names
zinc finger protein 762
zinc finger protein interacting with K protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010879.4NP_001010879.2  zinc finger protein interacting with ribonucleoprotein K

    See identical proteins and their annotated locations for NP_001010879.2

    Status: VALIDATED

    Source sequence(s)
    AC003682, AK092538, BC103958
    Consensus CDS
    CCDS33135.1
    UniProtKB/Swiss-Prot
    Q3SY52
    UniProtKB/TrEMBL
    B3KS08
    Related
    ENSP00000472867.1, ENST00000597850.2
    Conserved Domains (5) summary
    smart00349
    Location:2768
    KRAB; krueppel associated box
    COG5048
    Location:269449
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:381401
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2766
    KRAB; KRAB box
    pfam13465
    Location:394418
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001321145.2NP_001308074.1  zinc finger protein interacting with ribonucleoprotein K

    Status: VALIDATED

    Source sequence(s)
    AC003682, AK128340, BC103957, DB480028
    Consensus CDS
    CCDS82407.1
    UniProtKB/Swiss-Prot
    Q3SY52
    UniProtKB/TrEMBL
    B3KY01, F5H435
    Related
    ENSP00000438487.1, ENST00000536878.6
    Conserved Domains (5) summary
    smart00349
    Location:1455
    KRAB; krueppel associated box
    COG5048
    Location:256436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:368388
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:381405
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001321146.2NP_001308075.1  zinc finger protein interacting with ribonucleoprotein K

    Status: VALIDATED

    Source sequence(s)
    AC003682, BC103957, BC103959, DB277510
    Consensus CDS
    CCDS82408.1
    UniProtKB/Swiss-Prot
    Q3SY52
    Related
    ENSP00000468937.1, ENST00000599456.1
    Conserved Domains (3) summary
    COG5048
    Location:214394
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:339363
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001321147.2NP_001308076.1  zinc finger protein interacting with ribonucleoprotein K

    Status: VALIDATED

    Source sequence(s)
    AC003682, BC103957, DA101277, DN993640
    UniProtKB/Swiss-Prot
    Q3SY52
    Conserved Domains (2) summary
    COG5048
    Location:166346
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:278298
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57583642..57593890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526762.1XP_011525064.1  zinc finger protein interacting with ribonucleoprotein K isoform X2

    Conserved Domains (5) summary
    smart00349
    Location:849
    KRAB; krueppel associated box
    COG5048
    Location:250430
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:362382
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:375399
    zf-H2C2_2; Zinc-finger double domain
  2. XM_011526765.2XP_011525067.1  zinc finger protein interacting with ribonucleoprotein K isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:233413
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:358382
    zf-H2C2_2; Zinc-finger double domain
  3. XM_011526761.1XP_011525063.1  zinc finger protein interacting with ribonucleoprotein K isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:255435
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:367387
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2052
    KRAB; KRAB box
    pfam13465
    Location:380404
    zf-H2C2_2; Zinc-finger double domain
  4. XM_011526763.1XP_011525065.1  zinc finger protein interacting with ribonucleoprotein K isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:242422
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:354374
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1039
    KRAB; KRAB box
    pfam13465
    Location:367391
    zf-H2C2_2; Zinc-finger double domain
  5. XM_011526766.2XP_011525068.1  zinc finger protein interacting with ribonucleoprotein K isoform X5

    See identical proteins and their annotated locations for XP_011525068.1

    UniProtKB/Swiss-Prot
    Q3SY52
    Conserved Domains (3) summary
    COG5048
    Location:214394
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:339363
    zf-H2C2_2; Zinc-finger double domain
  6. XM_011526767.3XP_011525069.1  zinc finger protein interacting with ribonucleoprotein K isoform X6

    See identical proteins and their annotated locations for XP_011525069.1

    UniProtKB/Swiss-Prot
    Q3SY52
    Conserved Domains (2) summary
    COG5048
    Location:166346
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:278298
    ZF_C2H2; C2H2 Zn finger [structural motif]
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