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Gpr107 G protein-coupled receptor 107 [ Mus musculus (house mouse) ]

Gene ID: 277463, updated on 8-Dec-2022

Summary

Official Symbol
Gpr107provided by MGI
Official Full Name
G protein-coupled receptor 107provided by MGI
Primary source
MGI:MGI:2139054
See related
Ensembl:ENSMUSG00000000194 AllianceGenome:MGI:2139054
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1624; C530034M11; 9930033D15Rik
Summary
Enables clathrin heavy chain binding activity. Acts upstream of or within clathrin-dependent endocytosis. Located in clathrin-coated vesicle and early endosome. Orthologous to human GPR107 (G protein-coupled receptor 107). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 14.2), colon adult (RPKM 13.4) and 28 other tissues See more
Orthologs
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Genomic context

See Gpr107 in Genome Data Viewer
Location:
2; 2 B
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (31042099..31106579)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (31152102..31216567)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39786 Neighboring gene ubiquitin specific peptidase 20 Neighboring gene formin binding protein 1 Neighboring gene RIKEN cDNA D330023K18 gene Neighboring gene predicted gene, 22516 Neighboring gene neuronal calcium sensor 1 Neighboring gene hemicentin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables clathrin heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables clathrin heavy chain binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in clathrin-dependent endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within clathrin-dependent endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in clathrin-coated vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178760.4NP_848875.2  protein GPR107 precursor

    See identical proteins and their annotated locations for NP_848875.2

    Status: VALIDATED

    Source sequence(s)
    AK030433, AK034815, BY286814
    Consensus CDS
    CCDS15895.1
    UniProtKB/Swiss-Prot
    Q8BTW1, Q8BUV8
    UniProtKB/TrEMBL
    Q148Z6
    Related
    ENSMUSP00000056739.6, ENSMUST00000056433.7
    Conserved Domains (1) summary
    pfam06814
    Location:214504
    Lung_7-TM_R; Lung seven transmembrane receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    31042099..31106579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001782976.3 RNA Sequence