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ZBTB32 zinc finger and BTB domain containing 32 [ Homo sapiens (human) ]

Gene ID: 27033, updated on 11-Jun-2021

Summary

Official Symbol
ZBTB32provided by HGNC
Official Full Name
zinc finger and BTB domain containing 32provided by HGNC
Primary source
HGNC:HGNC:16763
See related
Ensembl:ENSG00000011590 MIM:605859
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Rog; FAXF; FAZF; TZFP; ZNF538
Expression
Biased expression in testis (RPKM 13.5), lymph node (RPKM 1.5) and 2 other tissues See more
Orthologs
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Genomic context

See ZBTB32 in Genome Data Viewer
Location:
19q13.12
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (35704481..35717048)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36195460..36207940)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene UPK1A antisense RNA 1 Neighboring gene uroplakin 1A Neighboring gene thymidylate synthetase pseudogene 2 Neighboring gene lysine methyltransferase 2B Neighboring gene IGF like family receptor 1 Neighboring gene U2 small nuclear RNA auxiliary factor 1 like 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 32
Names
FANCC-interacting protein
fanconi anemia zinc finger protein
repressor of GATA
testis zinc finger protein
zinc finger protein 538

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001316902.2NP_001303831.1  zinc finger and BTB domain-containing protein 32 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AF130255, HY027719, HY039545
    UniProtKB/Swiss-Prot
    Q9Y2Y4
    Conserved Domains (2) summary
    sd00017
    Location:98118
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:111132
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001316903.2NP_001303832.1  zinc finger and BTB domain-containing protein 32 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction and lacks an alternate exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AF130255, BX095236, HY027719
    UniProtKB/Swiss-Prot
    Q9Y2Y4
    Conserved Domains (2) summary
    sd00017
    Location:4363
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl27760
    Location:4191
    COG5048; FOG: Zn-finger [General function prediction only]
  3. NM_014383.3NP_055198.1  zinc finger and BTB domain-containing protein 32 isoform 1

    See identical proteins and their annotated locations for NP_055198.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AF130255, HY027719
    Consensus CDS
    CCDS12471.1
    UniProtKB/Swiss-Prot
    Q9Y2Y4
    Related
    ENSP00000376035.1, ENST00000392197.7
    Conserved Domains (3) summary
    COG5048
    Location:373423
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:375395
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02518
    Location:23109
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    35704481..35717048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026591.1XP_016882080.1  zinc finger and BTB domain-containing protein 32 isoform X4

  2. XM_011526718.2XP_011525020.1  zinc finger and BTB domain-containing protein 32 isoform X2

    See identical proteins and their annotated locations for XP_011525020.1

    UniProtKB/Swiss-Prot
    Q9Y2Y4
    Conserved Domains (3) summary
    COG5048
    Location:373423
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:375395
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02518
    Location:23109
    BTB; BTB/POZ domain
  3. XM_024451451.1XP_024307219.1  zinc finger and BTB domain-containing protein 32 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:373423
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:375395
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02518
    Location:23109
    BTB; BTB/POZ domain
  4. XM_017026588.1XP_016882077.1  zinc finger and BTB domain-containing protein 32 isoform X1

  5. XM_017026590.1XP_016882079.1  zinc finger and BTB domain-containing protein 32 isoform X3

  6. XM_017026592.1XP_016882081.1  zinc finger and BTB domain-containing protein 32 isoform X5

RNA

  1. XR_001753659.1 RNA Sequence

  2. XR_935793.2 RNA Sequence

    Related
    ENST00000481182.1
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