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Zfp384 zinc finger protein 384 [ Mus musculus (house mouse) ]

Gene ID: 269800, updated on 12-May-2024

Summary

Official Symbol
Zfp384provided by MGI
Official Full Name
zinc finger protein 384provided by MGI
Primary source
MGI:MGI:2443203
See related
Ensembl:ENSMUSG00000038346 AllianceGenome:MGI:2443203
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NP; Ciz; Nmp4; C130073D16Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SH3 domain binding activity. Predicted to be involved in nucleocytoplasmic transport; positive regulation of protein secretion; and positive regulation of transcription by RNA polymerase II. Predicted to be located in focal adhesion and nucleus. Is expressed in genitourinary system. Orthologous to human ZNF384 (zinc finger protein 384). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 25.8), thymus adult (RPKM 24.3) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp384 in Genome Data Viewer
Location:
6 F2; 6 59.17 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (124985980..125014833)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125009017..125037870)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3682 Neighboring gene COP9 signalosome subunit 7A Neighboring gene predicted gene, 23851 Neighboring gene STARR-seq mESC enhancer starr_17320 Neighboring gene STARR-seq mESC enhancer starr_17322 Neighboring gene PILR alpha associated neural protein Neighboring gene STARR-positive B cell enhancer ABC_E6488 Neighboring gene STARR-positive B cell enhancer ABC_E1711 Neighboring gene RIKEN cDNA 4930557K07 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:124959611-124959720 Neighboring gene STARR-positive B cell enhancer ABC_E1071 Neighboring gene STARR-seq mESC enhancer starr_17323 Neighboring gene STARR-positive B cell enhancer ABC_E6489 Neighboring gene inhibitor of growth family, member 4 Neighboring gene proacrosin binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (4)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in nucleocytoplasmic transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger protein 384
Names
nuclear matrix protein 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252083.1NP_001239012.1  zinc finger protein 384 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563, BY595967
    Consensus CDS
    CCDS57448.1
    UniProtKB/TrEMBL
    A0AA74KTG5, E9Q8N7, E9QAR1
    Related
    ENSMUSP00000108047.2, ENSMUST00000112428.8
    Conserved Domains (4) summary
    COG5048
    Location:285426
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:290310
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:288310
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:330357
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001347452.1NP_001334381.1  zinc finger protein 384 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563
    Consensus CDS
    CCDS90119.1
    UniProtKB/TrEMBL
    A0AA74KTG5, E9QAR4
    Conserved Domains (2) summary
    COG5048
    Location:209395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001372420.1NP_001359349.1  zinc finger protein 384 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563
    UniProtKB/TrEMBL
    Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:285440
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:351371
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001372422.1NP_001359351.1  zinc finger protein 384 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563
    Consensus CDS
    CCDS39631.1
    UniProtKB/TrEMBL
    E9Q1A5, Q6P3F1
    Related
    ENSMUSP00000108046.2, ENSMUST00000112427.8
    Conserved Domains (2) summary
    COG5048
    Location:209409
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:320340
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001372424.1NP_001359353.1  zinc finger protein 384 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563
    Consensus CDS
    CCDS39631.1
    UniProtKB/TrEMBL
    E9Q1A5, Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:209409
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:320340
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_175557.5NP_780766.3  zinc finger protein 384 isoform 1

    See identical proteins and their annotated locations for NP_780766.3

    Status: VALIDATED

    Source sequence(s)
    AC134529, AC164563, BB662626, BY261721, BY595967
    Consensus CDS
    CCDS39631.1
    UniProtKB/TrEMBL
    E9Q1A5, Q6P3F1
    Related
    ENSMUSP00000081296.6, ENSMUST00000084275.12
    Conserved Domains (2) summary
    COG5048
    Location:209409
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:320340
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    124985980..125014833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506201.3XP_006506264.1  zinc finger protein 384 isoform X1

    See identical proteins and their annotated locations for XP_006506264.1

    UniProtKB/TrEMBL
    Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:285440
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:351371
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_006506204.4XP_006506267.1  zinc finger protein 384 isoform X6

    UniProtKB/TrEMBL
    A0AA74KTG5, E9QAR4
    Conserved Domains (2) summary
    COG5048
    Location:209395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_036166185.1XP_036022078.1  zinc finger protein 384 isoform X6

    UniProtKB/TrEMBL
    A0AA74KTG5, E9QAR4
    Conserved Domains (2) summary
    COG5048
    Location:209395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_036166189.1XP_036022082.1  zinc finger protein 384 isoform X9

    Conserved Domains (2) summary
    COG5048
    Location:64264
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:175195
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_036166186.1XP_036022079.1  zinc finger protein 384 isoform X7

    UniProtKB/TrEMBL
    D3YX49
    Related
    ENSMUSP00000086354.3, ENSMUST00000054553.11
    Conserved Domains (4) summary
    COG5048
    Location:193379
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:243263
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:241263
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:283310
    zf-H2C2_2; Zinc-finger double domain
  6. XM_036166187.1XP_036022080.1  zinc finger protein 384 isoform X9

    Conserved Domains (2) summary
    COG5048
    Location:64264
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:175195
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_030255423.1XP_030111283.1  zinc finger protein 384 isoform X8

    Conserved Domains (2) summary
    COG5048
    Location:140295
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_036166190.1XP_036022083.1  zinc finger protein 384 isoform X10

    Conserved Domains (2) summary
    COG5048
    Location:140281
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:145165
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_036166191.1XP_036022084.1  zinc finger protein 384 isoform X11

    Conserved Domains (2) summary
    COG5048
    Location:64250
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:114134
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. XM_030255424.1XP_030111284.1  zinc finger protein 384 isoform X12

    Conserved Domains (3) summary
    COG5048
    Location:22177
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:138190
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:88108
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. XM_006506202.3XP_006506265.1  zinc finger protein 384 isoform X2

    UniProtKB/TrEMBL
    Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:269424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:335355
    ZF_C2H2; C2H2 Zn finger [structural motif]
  12. XM_036166183.1XP_036022076.1  zinc finger protein 384 isoform X5

    UniProtKB/TrEMBL
    A0AA74KTG5
    Conserved Domains (4) summary
    COG5048
    Location:269410
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:274294
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:272294
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:314341
    zf-H2C2_2; Zinc-finger double domain
  13. XM_030255421.1XP_030111281.1  zinc finger protein 384 isoform X3

    UniProtKB/TrEMBL
    E9QAR6, Q6P3F1
    Related
    ENSMUSP00000108043.2, ENSMUST00000112424.2
    Conserved Domains (2) summary
    COG5048
    Location:193393
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:304324
    ZF_C2H2; C2H2 Zn finger [structural motif]
  14. XM_006506205.5XP_006506268.1  zinc finger protein 384 isoform X8

    Conserved Domains (2) summary
    COG5048
    Location:140295
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
  15. XM_036166188.1XP_036022081.1  zinc finger protein 384 isoform X9

    Conserved Domains (2) summary
    COG5048
    Location:64264
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:175195
    ZF_C2H2; C2H2 Zn finger [structural motif]
  16. XM_036166192.1XP_036022085.1  zinc finger protein 384 isoform X11

    Conserved Domains (2) summary
    COG5048
    Location:64250
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:114134
    ZF_C2H2; C2H2 Zn finger [structural motif]
  17. XM_030255425.2XP_030111285.1  zinc finger protein 384 isoform X12

    Conserved Domains (3) summary
    COG5048
    Location:22177
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:138190
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:88108
    ZF_C2H2; C2H2 Zn finger [structural motif]
  18. XM_006506200.5XP_006506263.1  zinc finger protein 384 isoform X1

    See identical proteins and their annotated locations for XP_006506263.1

    UniProtKB/TrEMBL
    Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:285440
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:351371
    ZF_C2H2; C2H2 Zn finger [structural motif]
  19. XM_036166182.1XP_036022075.1  zinc finger protein 384 isoform X4

    UniProtKB/TrEMBL
    A0AA74KTG5, E9Q8N7, E9QAR1
    Related
    ENSMUSP00000037986.11, ENSMUST00000046064.17
    Conserved Domains (4) summary
    COG5048
    Location:285426
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:290310
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:288310
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:330357
    zf-H2C2_2; Zinc-finger double domain
  20. XM_036166193.1XP_036022086.1  zinc finger protein 384 isoform X12

    Conserved Domains (3) summary
    COG5048
    Location:22177
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:138190
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:88108
    ZF_C2H2; C2H2 Zn finger [structural motif]
  21. XM_036166184.1XP_036022077.1  zinc finger protein 384 isoform X6

    UniProtKB/TrEMBL
    A0AA74KTG5, E9QAR4
    Related
    ENSMUSP00000108044.2, ENSMUST00000112425.8
    Conserved Domains (2) summary
    COG5048
    Location:209395
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  22. XM_030255419.2XP_030111279.1  zinc finger protein 384 isoform X2

    UniProtKB/TrEMBL
    Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:269424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:335355
    ZF_C2H2; C2H2 Zn finger [structural motif]
  23. XM_030255422.2XP_030111282.1  zinc finger protein 384 isoform X3

    UniProtKB/TrEMBL
    E9QAR6, Q6P3F1
    Conserved Domains (2) summary
    COG5048
    Location:193393
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:304324
    ZF_C2H2; C2H2 Zn finger [structural motif]