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MPV17L MPV17 mitochondrial inner membrane protein like [ Homo sapiens (human) ]

Gene ID: 255027, updated on 2-Mar-2021

Summary

Official Symbol
MPV17Lprovided by HGNC
Official Full Name
MPV17 mitochondrial inner membrane protein likeprovided by HGNC
Primary source
HGNC:HGNC:26827
See related
Ensembl:ENSG00000156968 MIM:618100
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
M-LPH; MLPH1; MLPH2; MPV17L1
Expression
Broad expression in kidney (RPKM 1.8), duodenum (RPKM 1.5) and 20 other tissues See more
Orthologs
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Genomic context

See MPV17L in Genome Data Viewer
Location:
16p13.11
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (15395569..15413271)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (15489611..15507128)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107987241 Neighboring gene uncharacterized LOC105371103 Neighboring gene nuclear pore complex interacting protein family member A5 Neighboring gene bMERB domain containing 1 Neighboring gene Sharpr-MPRA regulatory region 1380 Neighboring gene uncharacterized LOC105371102

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39599, MGC70356

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mpv17-like protein
Names
M-LP homolog
MPV17 mitochondrial membrane protein-like
Mpv17-like protein type 1
Mpv17-like protein type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128423.2NP_001121895.1  mpv17-like protein isoform 1

    See identical proteins and their annotated locations for NP_001121895.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
    Source sequence(s)
    AC140504, BM838624, DQ004255
    Consensus CDS
    CCDS45421.1
    UniProtKB/Swiss-Prot
    Q2QL34
    Related
    ENSP00000379669.3, ENST00000396385.4
    Conserved Domains (1) summary
    pfam04117
    Location:107166
    Mpv17_PMP22; Mpv17 / PMP22 family
  2. NM_173803.4NP_776164.2  mpv17-like protein isoform 2

    See identical proteins and their annotated locations for NP_776164.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate segment, which shifts the reading frame, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus when it is compared to isoform 1.
    Source sequence(s)
    AC140504, BM838624, DQ004256
    Consensus CDS
    CCDS10560.1
    UniProtKB/Swiss-Prot
    Q2QL34
    Related
    ENSP00000287594.6, ENST00000287594.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    15395569..15413271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023108.1XP_016878597.1  mpv17-like protein isoform X1

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187607.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    1053717..1071250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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