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Zfp668 zinc finger protein 668 [ Mus musculus (house mouse) ]

Gene ID: 244219, updated on 5-Jan-2023

Summary

Official Symbol
Zfp668provided by MGI
Official Full Name
zinc finger protein 668provided by MGI
Primary source
MGI:MGI:2442943
See related
Ensembl:ENSMUSG00000049728 AllianceGenome:MGI:2442943
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf668; E130018B19Rik
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Orthologous to human ZNF668 (zinc finger protein 668). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 4.7), whole brain E14.5 (RPKM 3.7) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp668 in Genome Data Viewer
Location:
7; 7 F3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127460197..127476008, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127861025..127876836, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene syntaxin 1B Neighboring gene syntaxin 4A (placental) Neighboring gene zinc finger protein 646 Neighboring gene protease, serine 53 Neighboring gene vitamin K epoxide reductase complex, subunit 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC40890

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362189.1NP_001349118.1  zinc finger protein 668

    Status: VALIDATED

    Source sequence(s)
    AC149222
    Consensus CDS
    CCDS21881.1
    UniProtKB/Swiss-Prot
    Q8C8B7
    Related
    ENSMUSP00000101870.2, ENSMUST00000106263.8
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001362190.1NP_001349119.1  zinc finger protein 668

    Status: VALIDATED

    Source sequence(s)
    AC149222
    Consensus CDS
    CCDS21881.1
    UniProtKB/Swiss-Prot
    Q8C8B7
    Related
    ENSMUSP00000101869.2, ENSMUST00000106262.2
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001362191.1NP_001349120.1  zinc finger protein 668

    Status: VALIDATED

    Source sequence(s)
    AC149222
    Consensus CDS
    CCDS21881.1
    UniProtKB/Swiss-Prot
    Q8C8B7
    Related
    ENSMUSP00000101868.2, ENSMUST00000106261.8
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001362192.1NP_001349121.1  zinc finger protein 668

    Status: VALIDATED

    Source sequence(s)
    AC149222
    Consensus CDS
    CCDS21881.1
    UniProtKB/Swiss-Prot
    Q8C8B7
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_146259.4NP_666371.1  zinc finger protein 668

    See identical proteins and their annotated locations for NP_666371.1

    Status: VALIDATED

    Source sequence(s)
    AC149222, AK053438, BB612340
    Consensus CDS
    CCDS21881.1
    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Related
    ENSMUSP00000056105.6, ENSMUST00000054415.12
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127460197..127476008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322256.3XP_017177745.1  zinc finger protein 668 isoform X1

    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_036153124.1XP_036009017.1  zinc finger protein 668 isoform X1

    UniProtKB/Swiss-Prot
    Q8C8B7
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_006507848.4XP_006507911.1  zinc finger protein 668 isoform X1

    See identical proteins and their annotated locations for XP_006507911.1

    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_006507851.5XP_006507914.1  zinc finger protein 668 isoform X1

    See identical proteins and their annotated locations for XP_006507914.1

    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006507850.4XP_006507913.1  zinc finger protein 668 isoform X1

    See identical proteins and their annotated locations for XP_006507913.1

    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_030242589.2XP_030098449.1  zinc finger protein 668 isoform X1

    UniProtKB/Swiss-Prot
    Q8C8B7
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_036153123.1XP_036009016.1  zinc finger protein 668 isoform X1

    UniProtKB/Swiss-Prot
    Q8C8B7
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_017322254.3XP_017177743.1  zinc finger protein 668 isoform X1

    UniProtKB/Swiss-Prot
    Q8C8B7, Q8K2R5
    Conserved Domains (2) summary
    COG5048
    Location:65419
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226246
    ZF_C2H2; C2H2 Zn finger [structural motif]