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Zbtb37 zinc finger and BTB domain containing 37 [ Mus musculus (house mouse) ]

Gene ID: 240869, updated on 8-Dec-2022

Summary

Official Symbol
Zbtb37provided by MGI
Official Full Name
zinc finger and BTB domain containing 37provided by MGI
Primary source
MGI:MGI:2444467
See related
Ensembl:ENSMUSG00000043467 AllianceGenome:MGI:2444467
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D430004I08Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. Is expressed in early conceptus and genitourinary system. Orthologous to human ZBTB37 (zinc finger and BTB domain containing 37). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Zbtb37 in Genome Data Viewer
Location:
1; 1 H2.1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (160830492..160862432, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (161002922..161034864, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RING CCCH (C3H) domains 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Neighboring gene predicted gene, 26224 Neighboring gene predicted gene, 22489 Neighboring gene growth arrest specific 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356489.1NP_001343418.1  zinc finger and BTB domain-containing protein 37

    Status: VALIDATED

    Source sequence(s)
    AC163327
    Consensus CDS
    CCDS15412.1
    UniProtKB/TrEMBL
    Q8C3U9
    Related
    ENSMUSP00000125417.3, ENSMUST00000159250.9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  2. NM_173424.4NP_775600.1  zinc finger and BTB domain-containing protein 37

    See identical proteins and their annotated locations for NP_775600.1

    Status: VALIDATED

    Source sequence(s)
    AC163327
    Consensus CDS
    CCDS15412.1
    UniProtKB/TrEMBL
    Q8C3U9
    Related
    ENSMUSP00000125253.3, ENSMUST00000162226.9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_151478.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC163327
  2. NR_151479.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC163327

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    160830492..160862432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164847.1XP_036020740.1  zinc finger and BTB domain-containing protein 37 isoform X3

    UniProtKB/TrEMBL
    F7ALN1
    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
  2. XM_030254006.2XP_030109866.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  3. XM_030254021.2XP_030109881.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  4. XM_030254007.2XP_030109867.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  5. XM_030254027.2XP_030109887.1  zinc finger and BTB domain-containing protein 37 isoform X3

    UniProtKB/TrEMBL
    F7ALN1
    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
  6. XM_030254014.2XP_030109874.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  7. XM_036164844.1XP_036020737.1  zinc finger and BTB domain-containing protein 37 isoform X3

    UniProtKB/TrEMBL
    F7ALN1
    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
  8. XM_030254009.2XP_030109869.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  9. XM_036164845.1XP_036020738.1  zinc finger and BTB domain-containing protein 37 isoform X3

    UniProtKB/TrEMBL
    F7ALN1
    Related
    ENSMUSP00000129965.3, ENSMUST00000171748.3
    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
  10. XM_011238812.3XP_011237114.1  zinc finger and BTB domain-containing protein 37 isoform X1

    See identical proteins and their annotated locations for XP_011237114.1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  11. XM_011238815.3XP_011237117.1  zinc finger and BTB domain-containing protein 37 isoform X1

    See identical proteins and their annotated locations for XP_011237117.1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  12. XM_030254017.2XP_030109877.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  13. XM_036164829.1XP_036020722.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  14. XM_030254010.2XP_030109870.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  15. XM_030254019.2XP_030109879.1  zinc finger and BTB domain-containing protein 37 isoform X1

    UniProtKB/TrEMBL
    Q8C3U9
    Conserved Domains (4) summary
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
    pfam00096
    Location:403425
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:418440
    zf-H2C2_2; Zinc-finger double domain
  16. XM_036164837.1XP_036020730.1  zinc finger and BTB domain-containing protein 37 isoform X2

    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)
  17. XM_036164836.1XP_036020729.1  zinc finger and BTB domain-containing protein 37 isoform X2

    Conserved Domains (1) summary
    cd18222
    Location:9131
    BTB_POZ_ZBTB37; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 37 (ZBTB37)