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RBFOX2 RNA binding fox-1 homolog 2 [ Homo sapiens (human) ]

Gene ID: 23543, updated on 9-Dec-2018

Summary

Official Symbol
RBFOX2provided by HGNC
Official Full Name
RNA binding fox-1 homolog 2provided by HGNC
Primary source
HGNC:HGNC:9906
See related
Ensembl:ENSG00000100320 MIM:612149
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3
Summary
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in endometrium (RPKM 22.3), ovary (RPKM 20.4) and 23 other tissues See more
Orthologs

Genomic context

See RBFOX2 in Genome Data Viewer
Location:
22q12.3
Exon count:
24
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 22 NC_000022.11 (35738734..36028892, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (36134783..36424679, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 pseudogene 3 Neighboring gene apolipoprotein L5 Neighboring gene ribosomal protein L41 pseudogene 3 Neighboring gene NADH:ubiquinone oxidoreductase subunit A9 pseudogene 1 Neighboring gene uncharacterized LOC102723507 Neighboring gene apolipoprotein L3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • FGFR2 alternative splicing, organism-specific biosystem (from REACTOME)
    FGFR2 alternative splicing, organism-specific biosystemAlternative splicing of the FGFR2 nascent mRNA generates an epithelial specific isoform (FGFR2 IIIb) and a mesenchymal specific isoform (FGFR2 IIIc). The inclusion of exon 8 in FGFR2 IIIb or exon 9 ...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signaling by FGFR, organism-specific biosystem (from REACTOME)
    Signaling by FGFR, organism-specific biosystemThe 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosin...
  • Signaling by FGFR2, organism-specific biosystem (from REACTOME)
    Signaling by FGFR2, organism-specific biosystemThe 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosin...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
RNA metabolic process TAS
Traceable Author Statement
more info
PubMed 
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 
fibroblast growth factor receptor signaling pathway TAS
Traceable Author Statement
more info
 
intracellular estrogen receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuromuscular process controlling balance IEA
Inferred from Electronic Annotation
more info
 
radial glia guided migration of Purkinje cell IEA
Inferred from Electronic Annotation
more info
 
regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of alternative mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell proliferation TAS
Traceable Author Statement
more info
PubMed 
regulation of definitive erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RNA binding protein fox-1 homolog 2
Names
RNA binding protein, fox-1 homolog 2
RNA-binding motif protein 9
fox-1 homolog B
fox-1 homologue
hexaribonucleotide-binding protein 2
repressor of tamoxifen transcriptional activity

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029628.1 RefSeqGene

    Range
    5001..294805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001031695.3NP_001026865.1  RNA binding protein fox-1 homolog 2 isoform 1

    See identical proteins and their annotated locations for NP_001026865.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AA610054, AL049748, BC025281, DA493176
    Consensus CDS
    CCDS46700.1
    UniProtKB/Swiss-Prot
    O43251
    Related
    ENSP00000391670.2, ENST00000449924.6
    Conserved Domains (3) summary
    cd12407
    Location:111186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:255352
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:95261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. NM_001082576.2NP_001076045.1  RNA binding protein fox-1 homolog 2 isoform 3

    See identical proteins and their annotated locations for NP_001076045.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 3) is 4-aa shorter than isoform 1.
    Source sequence(s)
    AA610054, AL049748, CR456559, DA493176
    Consensus CDS
    CCDS46701.1
    UniProtKB/Swiss-Prot
    O43251
    Related
    ENSP00000405651.2, ENST00000416721.6
    Conserved Domains (3) summary
    cd12407
    Location:111186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251348
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:95247
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  3. NM_001082577.2NP_001076046.1  RNA binding protein fox-1 homolog 2 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon in the 3' coding region that results in a frameshift, compared to variant 1. The resulting protein (isoform 4) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AA610054, AL049748, AY960684, DA493176
    Consensus CDS
    CCDS46699.1
    UniProtKB/Swiss-Prot
    O43251
    Related
    ENSP00000407855.2, ENST00000414461.6
    Conserved Domains (3) summary
    COG0724
    Location:70195
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:111186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:255303
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  4. NM_001082578.3NP_001076047.1  RNA binding protein fox-1 homolog 2 isoform 5

    See identical proteins and their annotated locations for NP_001076047.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) contains a distinct 5' UTR, 5' CDS, and uses an alternate in-frame splice site in the coding region, compared to variant 1. The resulting protein (isoform 5) is longer and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AA610054, AL049748, DB461443, DQ778625, Z95114
    Consensus CDS
    CCDS43013.1
    UniProtKB/Swiss-Prot
    O43251
    Related
    ENSP00000413035.2, ENST00000438146.6
    Conserved Domains (3) summary
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:326423
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:166332
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  5. NM_001082579.2NP_001076048.1  RNA binding protein fox-1 homolog 2 isoform 6

    See identical proteins and their annotated locations for NP_001076048.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) contains a distinct 5' UTR and 5' CDS, compared to variant 1. The resulting protein (isoform 6) is longer and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AA610054, AL049748, AY072786, DB461443
    Conserved Domains (3) summary
    COG0724
    Location:140265
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:181256
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:325422
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  6. NM_001349982.1NP_001336911.1  RNA binding protein fox-1 homolog 2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 8) has distinct N- and C-termini and is longer than isoform 1.
    Source sequence(s)
    AA610054, AL035800, AL049748, CR456559, DA776762, HY155887, HY351263
    Conserved Domains (3) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273330
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:117269
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  7. NM_001349983.1NP_001336912.1  RNA binding protein fox-1 homolog 2 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) uses an alternate in-frame splice site in its 3' coding region and contains an alternate exon in the 3' coding region, which results in a frameshift and a shorter 3' UTR, compared to variant 1. The resulting protein (isoform 7) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AA610054, AL049748, CN399960, CR456559, HY351263
    Conserved Domains (3) summary
    cd12407
    Location:111186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251308
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:95247
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  8. NM_001349989.1NP_001336918.1  RNA binding protein fox-1 homolog 2 isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon, compared to variant 1. The resulting protein (isoform 9) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (3) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:277374
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:117283
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  9. NM_001349990.1NP_001336919.1  RNA binding protein fox-1 homolog 2 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon, compared to variant 1. The resulting protein (isoform 10) has a distinct N-terminus and is longer than isoform 1. Isoforms 10 and 15 are identical in length but have different sequences.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (3) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273370
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:117269
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  10. NM_001349991.1NP_001336920.1  RNA binding protein fox-1 homolog 2 isoform 11

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 11) has distinct N- and C-termini and is longer than isoform 1.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (3) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:277334
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:117283
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  11. NM_001349992.1NP_001336921.1  RNA binding protein fox-1 homolog 2 isoform 12

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 12) has distinct N- and C-termini and is longer than isoform 1.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (3) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:277325
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:117283
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  12. NM_001349994.1NP_001336923.1  RNA binding protein fox-1 homolog 2 isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 13) has distinct N- and C-termini and is longer than isoform 1.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (2) summary
    cd12407
    Location:133208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273321
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  13. NM_001349995.1NP_001336924.1  RNA binding protein fox-1 homolog 2 isoform 14

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 14) has distinct N- and C-termini and is shorter than isoform 1.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (3) summary
    COG0724
    Location:92167
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:246294
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:133172
    RRM_SF; RNA recognition motif (RRM) superfamily
  14. NM_001349996.1NP_001336925.1  RNA binding protein fox-1 homolog 2 isoform 15

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon, compared to variant 1. The resulting protein (isoform 15) has a distinct N- terminus and is longer than isoform 1. Isoforms 10 and 15 are identical in length but have different sequences.
    Source sequence(s)
    AL049748, AL079295, Z82217
    Conserved Domains (2) summary
    cd12407
    Location:134208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273370
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  15. NM_001349997.1NP_001336926.1  RNA binding protein fox-1 homolog 2 isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) uses an alternate in-frame splice site in its 3' coding region, compared to variant 1. The resulting protein (isoform 16) is longer compared to isoform 1.
    Source sequence(s)
    AK291460, AL049748, AL079295
    Conserved Domains (3) summary
    cd12407
    Location:112187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:256353
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:96262
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  16. NM_001349998.1NP_001336927.1  RNA binding protein fox-1 homolog 2 isoform 17

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) contains an alternate exon in the 3' coding region, which results in a frameshift and a shorter 3' UTR, compared to variant 1. The resulting protein (isoform 17) is longer and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AB649123, AL049748, AL079295
    Conserved Domains (3) summary
    cd12407
    Location:111186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:255312
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:95261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  17. NM_001349999.1NP_001336928.1  RNA binding protein fox-1 homolog 2 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) differs in the 5' UTR and has multiple differences in the coding region, including an alternate start codon and a translational frameshift, compared to variant 1. The resulting protein (isoform 18) has distinct N- and C-termini and is longer than isoform 1.
    Source sequence(s)
    AL049748, AL079295, DR006798
    Conserved Domains (2) summary
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:322419
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  18. NM_014309.3NP_055124.1  RNA binding protein fox-1 homolog 2 isoform 2

    See identical proteins and their annotated locations for NP_055124.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses two alternate in-frame splice sites in the coding region, and lacks an alternate exon in the 3' coding region that results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AA610054, AL009266, AL049748, DA493176
    Consensus CDS
    CCDS13921.1
    UniProtKB/Swiss-Prot
    O43251
    Related
    ENSP00000384944.2, ENST00000405409.6
    Conserved Domains (3) summary
    COG0724
    Location:95196
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:112187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252300
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p12 Primary Assembly

    Range
    35738734..36028892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028688.1XP_016884177.1  RNA binding protein fox-1 homolog 2 isoform X13

  2. XM_005261432.2XP_005261489.1  RNA binding protein fox-1 homolog 2 isoform X8

    See identical proteins and their annotated locations for XP_005261489.1

    Conserved Domains (3) summary
    COG0724
    Location:140265
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:181256
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:321418
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  3. XM_005261429.2XP_005261486.1  RNA binding protein fox-1 homolog 2 isoform X4

    Conserved Domains (3) summary
    COG0724
    Location:140265
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:181256
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:321378
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  4. XM_006724186.2XP_006724249.1  RNA binding protein fox-1 homolog 2 isoform X2

    Conserved Domains (3) summary
    COG0724
    Location:140265
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:181256
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:325382
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  5. XM_005261433.2XP_005261490.1  RNA binding protein fox-1 homolog 2 isoform X12

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:322370
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  6. XM_005261430.2XP_005261487.1  RNA binding protein fox-1 homolog 2 isoform X7

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:322420
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  7. XM_005261428.2XP_005261485.1  RNA binding protein fox-1 homolog 2 isoform X3

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:322379
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  8. XM_006724188.2XP_006724251.1  RNA binding protein fox-1 homolog 2 isoform X9

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:326374
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  9. XM_006724187.2XP_006724250.1  RNA binding protein fox-1 homolog 2 isoform X5

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:326424
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  10. XM_006724185.2XP_006724248.1  RNA binding protein fox-1 homolog 2 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:326383
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  11. XM_017028686.1XP_016884175.1  RNA binding protein fox-1 homolog 2 isoform X6

    Conserved Domains (3) summary
    COG0724
    Location:107208
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:124199
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:268325
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  12. XM_024452189.1XP_024307957.1  RNA binding protein fox-1 homolog 2 isoform X22

    Conserved Domains (3) summary
    cd12407
    Location:92167
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:236293
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:76242
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  13. XM_017028697.1XP_016884186.1  RNA binding protein fox-1 homolog 2 isoform X23

    Conserved Domains (3) summary
    COG0724
    Location:50175
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:91166
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:235292
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  14. XM_006724189.3XP_006724252.1  RNA binding protein fox-1 homolog 2 isoform X14

    Conserved Domains (3) summary
    COG0724
    Location:117218
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:134209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:278335
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  15. XM_017028687.2XP_016884176.1  RNA binding protein fox-1 homolog 2 isoform X10

  16. XM_024452188.1XP_024307956.1  RNA binding protein fox-1 homolog 2 isoform X11

    Conserved Domains (3) summary
    cd12407
    Location:155230
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:299356
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:139305
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  17. XM_024452191.1XP_024307959.1  RNA binding protein fox-1 homolog 2 isoform X24

    Conserved Domains (3) summary
    cd12407
    Location:107182
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:247344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:91243
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  18. XM_006724192.2XP_006724255.1  RNA binding protein fox-1 homolog 2 isoform X18

    Conserved Domains (3) summary
    COG0724
    Location:91192
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:108183
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252309
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  19. XM_017028691.1XP_016884180.1  RNA binding protein fox-1 homolog 2 isoform X16

  20. XM_017028690.1XP_016884179.1  RNA binding protein fox-1 homolog 2 isoform X15

  21. XM_017028698.1XP_016884187.1  RNA binding protein fox-1 homolog 2 isoform X26

  22. XM_017028696.1XP_016884185.1  RNA binding protein fox-1 homolog 2 isoform X21

    Related
    ENSP00000380470.2, ENST00000397303.6
    Conserved Domains (3) summary
    cd12407
    Location:112187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252349
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:96248
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  23. XM_017028693.1XP_016884182.1  RNA binding protein fox-1 homolog 2 isoform X19

    Conserved Domains (3) summary
    COG0724
    Location:95196
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:112187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252309
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  24. XM_006724191.1XP_006724254.1  RNA binding protein fox-1 homolog 2 isoform X17

    Conserved Domains (3) summary
    COG0724
    Location:95196
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:112187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:256313
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  25. XM_024452190.1XP_024307958.1  RNA binding protein fox-1 homolog 2 isoform X22

    Conserved Domains (3) summary
    cd12407
    Location:92167
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:236293
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:76242
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  26. XM_024452192.1XP_024307960.1  RNA binding protein fox-1 homolog 2 isoform X25

    Related
    ENSP00000352328.4, ENST00000359369.8
    Conserved Domains (3) summary
    cd12407
    Location:91166
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:231288
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:75227
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  27. XM_006724194.2XP_006724257.1  RNA binding protein fox-1 homolog 2 isoform X23

    Conserved Domains (3) summary
    COG0724
    Location:50175
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:91166
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:235292
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
  28. XM_006724193.3XP_006724256.1  RNA binding protein fox-1 homolog 2 isoform X20

    Conserved Domains (3) summary
    COG0724
    Location:165266
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12407
    Location:182257
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:326383
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

Reference GRCh38.p12 ALT_REF_LOCI_1

Genomic

  1. NT_187630.1 Reference GRCh38.p12 ALT_REF_LOCI_1

    Range
    59732..259897 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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