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Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 [ Mus musculus (house mouse) ]

Gene ID: 93686, updated on 29-Jan-2023

Summary

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Official Symbol
Rbfox2provided by MGI
Official Full Name
RNA binding protein, fox-1 homolog (C. elegans) 2provided by MGI
Primary source
MGI:MGI:1933973
See related
Ensembl:ENSMUSG00000033565 AllianceGenome:MGI:1933973
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fxh; Fbm2; Rbm9; Hrnbp2
Summary
Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of definitive erythrocyte differentiation. Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; nervous system development; and regulation of heart rate by cardiac conduction. Located in nucleus. Is expressed in several structures, including blastocyst; brain; dorsal root ganglion; early embryo; and limb. Orthologous to human RBFOX2 (RNA binding fox-1 homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 47.2), whole brain E14.5 (RPKM 43.2) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Rbfox2 in Genome Data Viewer
Location:
15; 15 D3
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76963190..77193058, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (77078990..77308434, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene myoglobin Neighboring gene apolipoprotein L 6 Neighboring gene RIKEN cDNA 1700109K24 gene Neighboring gene predicted gene, 24753 Neighboring gene predicted gene, 53899 Neighboring gene predicted gene, 24056 Neighboring gene predicted gene, 41352 Neighboring gene predicted gene, 49436

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure. Gu M, et al. Int J Mol Sci, 2023 Jan 9. PMID 36674797, Free PMC Article
  2. Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models. Freitag N, et al. Am J Reprod Immunol, 2021 Dec. PMID 34363260
  3. Identification of a classic nuclear localization signal at the N terminus that regulates the subcellular localization of Rbfox2 isoforms during differentiation of NMuMG and P19 cells. Wenzel M, et al. FEBS Lett, 2016 Dec. PMID 27859055
  4. Rbfox2 controls autoregulation in RNA-binding protein networks. Jangi M, et al. Genes Dev, 2014 Mar 15. PMID 24637117, Free PMC Article
  5. The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Braeutigam C, et al. Oncogene, 2014 Feb 27. PMID 23435423

See all (73) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure.
    Title: Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure.
  2. Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
    Title: Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
  3. RBFOX2 is required for establishing RNA regulatory networks essential for heart development.
    Title: RBFOX2 is required for establishing RNA regulatory networks essential for heart development.
  4. Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models.
    Title: Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models.
  5. The effect of Rbfox2 modulation on retinal transcriptome and visual function.
    Title: The effect of Rbfox2 modulation on retinal transcriptome and visual function.
  6. Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.
    Title: Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.
  7. Expression of Rbfox2 is essential for proper exon splicing of genes of the cGMP-PKG-Ca2+ pathway.
    Title: Genes of the cGMP-PKG-Ca(2+) signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2.
  8. Here, the authors demonstrate that splicing factor Rbfox2 is expressed in the neural crest cells (NCCs), and deletion of Rbfox2 in NCCs leads to cleft palate and defects in craniofacial bone development. RNA-Seq analysis revealed that Rbfox2 regulates splicing and expression of numerous genes essential for neural crest/craniofacial development.
    Title: Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate.
  9. Rbfox deletion did not cause a reduction in global protein synthesis, but it led to altered splicing of hundreds of gene transcripts, including capn3, which produced an active form of calpain3 protease.
    Title: Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis.
  10. RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure
    Title: RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.
Submit: New GeneRIF Correction See all GeneRIFs (23)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • 2810460A15Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
enables RNA binding ISO
Inferred from Sequence Orthology
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular estrogen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
acts_upstream_of_or_within neuromuscular process controlling balance IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within radial glia guided migration of Purkinje cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of definitive erythrocyte differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RNA binding protein fox-1 homolog 2
Names
Fyn-binding molecule 2
RNA-binding motif protein 9
fox-1 homolog B
fox-1 homolog Fxh
hexaribonucleotide-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110827.3 → NP_001104297.1  RNA binding protein fox-1 homolog 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843, AL772386
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A6P5QYR6
    Conserved Domains (3) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    TIGR01661
    Location:37 → 251
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:320 → 417
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  2. NM_001110828.3 → NP_001104298.1  RNA binding protein fox-1 homolog 2 isoform 4

    See identical proteins and their annotated locations for NP_001104298.1

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS49658.1
    UniProtKB/Swiss-Prot
    Q8BP71
    Related
    ENSMUSP00000130673.2, ENSMUST00000166610.8
    Conserved Domains (3) summary
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:256 → 353
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl25887
    Location:96 → 262
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. NM_001110829.3 → NP_001104299.1  RNA binding protein fox-1 homolog 2 isoform 5

    See identical proteins and their annotated locations for NP_001104299.1

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS49657.1
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A6P7PY87, A0A8C6HR19
    Related
    ENSMUSP00000154233.2, ENSMUST00000227314.2
    Conserved Domains (2) summary
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252 → 350
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  4. NM_001110830.3 → NP_001104300.1  RNA binding protein fox-1 homolog 2 isoform 6

    See identical proteins and their annotated locations for NP_001104300.1

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS88798.1
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A6P5QYS3
    Related
    ENSMUSP00000153751.2, ENSMUST00000228087.2
    Conserved Domains (3) summary
    TIGR01645
    Location:96 → 248
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252 → 349
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  5. NM_001286417.2 → NP_001273346.1  RNA binding protein fox-1 homolog 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS88797.1
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A2K6EDK7, A0A8C6MZP3
    Related
    ENSMUSP00000129372.3, ENSMUST00000111581.4
    Conserved Domains (2) summary
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252 → 300
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  6. NM_001286418.2 → NP_001273347.1  RNA binding protein fox-1 homolog 2 isoform 8

    See identical proteins and their annotated locations for NP_001273347.1

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS88795.1
    UniProtKB/Swiss-Prot
    Q8BP71
    Related
    ENSMUSP00000154810.2, ENSMUST00000227930.2
    Conserved Domains (1) summary
    pfam12414
    Location:158 → 255
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  7. NM_001286419.2 → NP_001273348.1  RNA binding protein fox-1 homolog 2 isoform 9

    See identical proteins and their annotated locations for NP_001273348.1

    Status: VALIDATED

    Source sequence(s)
    AL603843
    Consensus CDS
    CCDS88796.1
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A6P7Q289
    Related
    ENSMUSP00000154209.2, ENSMUST00000227533.2
    Conserved Domains (3) summary
    COG0724
    Location:70 → 145
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:220 → 318
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:111 → 150
    RRM_SF; RNA recognition motif (RRM) superfamily

  8. NM_001358770.2 → NP_001345699.1  RNA binding protein fox-1 homolog 2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843
    UniProtKB/TrEMBL
    A0A6P7PY77
    Conserved Domains (3) summary
    TIGR01645
    Location:118 → 270
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:134 → 209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:274 → 371
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  9. NM_001358772.2 → NP_001345701.1  RNA binding protein fox-1 homolog 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843
    Conserved Domains (2) summary
    cd12407
    Location:134 → 209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:274 → 331
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  10. NM_001412007.1 → NP_001398936.1  RNA binding protein fox-1 homolog 2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843, AL772386
    UniProtKB/TrEMBL
    A0A6P7QFR3

  11. NM_001412008.1 → NP_001398937.1  RNA binding protein fox-1 homolog 2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843, AL772386
    UniProtKB/TrEMBL
    A0A6P5RB53

  12. NM_001412009.1 → NP_001398938.1  RNA binding protein fox-1 homolog 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AL603843, AL772386

  13. NM_001412010.1 → NP_001398939.1  RNA binding protein fox-1 homolog 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AL603843, AL772386

  14. NM_001412011.1 → NP_001398940.1  RNA binding protein fox-1 homolog 2 isoform 37

    Status: VALIDATED

    Source sequence(s)
    AL603843, AL772386

  15. NM_001412012.1 → NP_001398941.1  RNA binding protein fox-1 homolog 2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AL603843, AL772386

  16. NM_001412013.1 → NP_001398942.1  RNA binding protein fox-1 homolog 2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AL603843, AL772386

  17. NM_001412014.1 → NP_001398943.1  RNA binding protein fox-1 homolog 2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843
    UniProtKB/TrEMBL
    A0A8C6HQV4

  18. NM_001412015.1 → NP_001398944.1  RNA binding protein fox-1 homolog 2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843
    UniProtKB/TrEMBL
    A0A6P7QFV0

  19. NM_001412016.1 → NP_001398945.1  RNA binding protein fox-1 homolog 2 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  20. NM_001412017.1 → NP_001398946.1  RNA binding protein fox-1 homolog 2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  21. NM_001412018.1 → NP_001398947.1  RNA binding protein fox-1 homolog 2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  22. NM_001412019.1 → NP_001398948.1  RNA binding protein fox-1 homolog 2 isoform 24

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  23. NM_001412020.1 → NP_001398949.1  RNA binding protein fox-1 homolog 2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  24. NM_001412021.1 → NP_001398950.1  RNA binding protein fox-1 homolog 2 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843

  25. NM_001412022.1 → NP_001398951.1  RNA binding protein fox-1 homolog 2 isoform 27

    Status: VALIDATED

    Source sequence(s)
    AL603843

  26. NM_001412023.1 → NP_001398952.1  RNA binding protein fox-1 homolog 2 isoform 28

    Status: VALIDATED

    Source sequence(s)
    AL603843

  27. NM_001412024.1 → NP_001398953.1  RNA binding protein fox-1 homolog 2 isoform 29

    Status: VALIDATED

    Source sequence(s)
    AL603843
    UniProtKB/TrEMBL
    A0A6P7QIA8

  28. NM_001412025.1 → NP_001398954.1  RNA binding protein fox-1 homolog 2 isoform 30

    Status: VALIDATED

    Source sequence(s)
    AL603843
    UniProtKB/TrEMBL
    A0A6P7QKR5, A0A8C6HS37

  29. NM_001412026.1 → NP_001398955.1  RNA binding protein fox-1 homolog 2 isoform 31

    Status: VALIDATED

    Source sequence(s)
    AL603843

  30. NM_001412027.1 → NP_001398956.1  RNA binding protein fox-1 homolog 2 isoform 38

    Status: VALIDATED

    Source sequence(s)
    AL603843

  31. NM_001412028.1 → NP_001398957.1  RNA binding protein fox-1 homolog 2 isoform 32

    Status: VALIDATED

    Source sequence(s)
    AL603843
    UniProtKB/TrEMBL
    A0A6P5RB59

  32. NM_001412029.1 → NP_001398958.1  RNA binding protein fox-1 homolog 2 isoform 33

    Status: VALIDATED

    Source sequence(s)
    AL603843

  33. NM_001412030.1 → NP_001398959.1  RNA binding protein fox-1 homolog 2 isoform 34

    Status: VALIDATED

    Source sequence(s)
    AL603843

  34. NM_001412031.1 → NP_001398960.1  RNA binding protein fox-1 homolog 2 isoform 35

    Status: VALIDATED

    Source sequence(s)
    AL603843

  35. NM_001412032.1 → NP_001398961.1  RNA binding protein fox-1 homolog 2 isoform 36

    Status: VALIDATED

    Source sequence(s)
    AL603843

  36. NM_053104.7 → NP_444334.3  RNA binding protein fox-1 homolog 2 isoform 1

    See identical proteins and their annotated locations for NP_444334.3

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843, AL772386
    Consensus CDS
    CCDS49659.1
    UniProtKB/Swiss-Prot
    Q8BP71, Q923W8
    UniProtKB/TrEMBL
    A0A6P5R847
    Related
    ENSMUSP00000130739.2, ENSMUST00000171751.10
    Conserved Domains (3) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    TIGR01661
    Location:37 → 251
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:324 → 421
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  37. NM_175387.4 → NP_780596.1  RNA binding protein fox-1 homolog 2 isoform 2

    See identical proteins and their annotated locations for NP_780596.1

    Status: VALIDATED

    Source sequence(s)
    AL591892, AL603843, AL772386
    Consensus CDS
    CCDS27598.1
    UniProtKB/Swiss-Prot
    Q8BP71
    UniProtKB/TrEMBL
    A0A6P5R852
    Related
    ENSMUSP00000048056.6, ENSMUST00000048145.13
    Conserved Domains (2) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:320 → 368
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

RNA

  1. NR_177995.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL603843

  2. NR_177996.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL603843

  3. NR_177997.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL603843

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    76963190..77193058 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248832.2 → XP_030104692.1  RNA binding protein fox-1 homolog 2 isoform X13

    Conserved Domains (2) summary
    cd12407
    Location:162 → 237
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:302 → 399
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  2. XM_030248830.2 → XP_030104690.1  RNA binding protein fox-1 homolog 2 isoform X10

    Conserved Domains (2) summary
    cd12407
    Location:162 → 237
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:302 → 359
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  3. XM_030248836.2 → XP_030104696.1  RNA binding protein fox-1 homolog 2 isoform X20

    Conserved Domains (2) summary
    pfam12414
    Location:272 → 369
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:163 → 202
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. XM_030248831.2 → XP_030104691.1  RNA binding protein fox-1 homolog 2 isoform X12

    Conserved Domains (2) summary
    cd12407
    Location:163 → 238
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:303 → 400
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  5. XM_030248829.2 → XP_030104689.1  RNA binding protein fox-1 homolog 2 isoform X9

    Conserved Domains (2) summary
    cd12407
    Location:163 → 238
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:303 → 360
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  6. XM_006521587.4 → XP_006521650.1  RNA binding protein fox-1 homolog 2 isoform X15

    UniProtKB/TrEMBL
    A0A6P7Q251
    Conserved Domains (3) summary
    COG0724
    Location:138 → 213
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:288 → 386
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:179 → 218
    RRM_SF; RNA recognition motif (RRM) superfamily

  7. XM_036159654.1 → XP_036015547.1  RNA binding protein fox-1 homolog 2 isoform X7

    Conserved Domains (2) summary
    pfam12414
    Location:319 → 417
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:179 → 254
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  8. XM_006521577.4 → XP_006521640.1  RNA binding protein fox-1 homolog 2 isoform X8

    Conserved Domains (2) summary
    cd12407
    Location:179 → 254
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:319 → 416
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  9. XM_006521570.4 → XP_006521633.1  RNA binding protein fox-1 homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A6P7QKQ5
    Conserved Domains (2) summary
    cd12407
    Location:179 → 254
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:319 → 376
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  10. XM_036159656.1 → XP_036015549.1  RNA binding protein fox-1 homolog 2 isoform X18

    Conserved Domains (2) summary
    pfam12414
    Location:289 → 337
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:180 → 219
    RRM_SF; RNA recognition motif (RRM) superfamily

  11. XM_036159655.1 → XP_036015548.1  RNA binding protein fox-1 homolog 2 isoform X14

    Conserved Domains (2) summary
    pfam12414
    Location:289 → 387
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:180 → 219
    RRM_SF; RNA recognition motif (RRM) superfamily

  12. XM_006521576.4 → XP_006521639.1  RNA binding protein fox-1 homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A6P7Q232
    Conserved Domains (3) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    TIGR01661
    Location:37 → 251
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:320 → 418
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  13. XM_017316809.3 → XP_017172298.1  RNA binding protein fox-1 homolog 2 isoform X3

    Conserved Domains (2) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:320 → 377
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  14. XM_006521580.4 → XP_006521643.1  RNA binding protein fox-1 homolog 2 isoform X11

    UniProtKB/TrEMBL
    A0A6P5R5R0
    Conserved Domains (3) summary
    TIGR01628
    Location:168 → 421
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:324 → 372
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  15. XM_006521574.4 → XP_006521637.1  RNA binding protein fox-1 homolog 2 isoform X5

    UniProtKB/TrEMBL
    A0A6P7QI90
    Conserved Domains (3) summary
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    TIGR01661
    Location:37 → 251
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:324 → 422
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  16. XM_006521568.4 → XP_006521631.1  RNA binding protein fox-1 homolog 2 isoform X1

    Conserved Domains (3) summary
    TIGR01645
    Location:164 → 330
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:324 → 380
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  17. XM_006521569.4 → XP_006521632.1  RNA binding protein fox-1 homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P7Q215
    Conserved Domains (3) summary
    TIGR01645
    Location:164 → 330
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:180 → 255
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:324 → 381
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  18. XM_030248835.2 → XP_030104695.1  RNA binding protein fox-1 homolog 2 isoform X19

    Conserved Domains (3) summary
    TIGR01645
    Location:117 → 269
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:133 → 208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273 → 370
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  19. XM_036159660.1 → XP_036015553.1  RNA binding protein fox-1 homolog 2 isoform X31

    Conserved Domains (2) summary
    pfam12414
    Location:243 → 340
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:134 → 173
    RRM_SF; RNA recognition motif (RRM) superfamily

  20. XM_030248833.2 → XP_030104693.1  RNA binding protein fox-1 homolog 2 isoform X16

    Conserved Domains (2) summary
    cd12407
    Location:134 → 209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:274 → 331
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  21. XM_030248839.2 → XP_030104699.1  RNA binding protein fox-1 homolog 2 isoform X23

    Conserved Domains (2) summary
    cd12407
    Location:134 → 209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:274 → 322
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  22. XM_030248841.2 → XP_030104701.1  RNA binding protein fox-1 homolog 2 isoform X25

    Conserved Domains (2) summary
    cd12407
    Location:133 → 208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273 → 321
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  23. XM_030248834.2 → XP_030104694.1  RNA binding protein fox-1 homolog 2 isoform X17

    Conserved Domains (2) summary
    cd12407
    Location:133 → 208
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:273 → 330
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  24. XM_036159659.1 → XP_036015552.1  RNA binding protein fox-1 homolog 2 isoform X29

    Conserved Domains (3) summary
    TIGR01645
    Location:91 → 243
    half-pint; poly-U binding splicing factor, half-pint family
    pfam12414
    Location:247 → 345
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:107 → 182
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  25. XM_036159658.1 → XP_036015551.1  RNA binding protein fox-1 homolog 2 isoform X28

    Conserved Domains (3) summary
    TIGR01645
    Location:92 → 244
    half-pint; poly-U binding splicing factor, half-pint family
    pfam12414
    Location:248 → 346
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:108 → 183
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  26. XM_036159657.1 → XP_036015550.1  RNA binding protein fox-1 homolog 2 isoform X24

    Conserved Domains (3) summary
    TIGR01645
    Location:102 → 254
    half-pint; poly-U binding splicing factor, half-pint family
    pfam12414
    Location:258 → 356
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:118 → 193
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  27. XM_006521593.5 → XP_006521656.1  RNA binding protein fox-1 homolog 2 isoform X32

    Conserved Domains (2) summary
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252 → 300
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  28. XM_030248846.2 → XP_030104706.1  RNA binding protein fox-1 homolog 2 isoform X33

    Conserved Domains (2) summary
    cd12407
    Location:111 → 186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251 → 299
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  29. XM_030248843.2 → XP_030104703.1  RNA binding protein fox-1 homolog 2 isoform X26

    Conserved Domains (2) summary
    cd12407
    Location:111 → 186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251 → 349
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  30. XM_030248844.2 → XP_030104704.1  RNA binding protein fox-1 homolog 2 isoform X27

    Conserved Domains (3) summary
    TIGR01645
    Location:95 → 247
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:111 → 186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251 → 348
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  31. XM_030248838.2 → XP_030104698.1  RNA binding protein fox-1 homolog 2 isoform X22

    Conserved Domains (3) summary
    TIGR01645
    Location:95 → 247
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:111 → 186
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:251 → 308
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  32. XM_030248847.2 → XP_030104707.1  RNA binding protein fox-1 homolog 2 isoform X34

    Conserved Domains (2) summary
    pfam12414
    Location:221 → 278
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:112 → 151
    RRM_SF; RNA recognition motif (RRM) superfamily

  33. XM_030248837.2 → XP_030104697.1  RNA binding protein fox-1 homolog 2 isoform X21

    Conserved Domains (2) summary
    cd12407
    Location:112 → 187
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:252 → 309
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  34. XM_030248849.1 → XP_030104709.1  RNA binding protein fox-1 homolog 2 isoform X35

    Conserved Domains (3) summary
    TIGR01645
    Location:76 → 228
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:92 → 167
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:232 → 329
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  35. XM_030248845.1 → XP_030104705.1  RNA binding protein fox-1 homolog 2 isoform X30

    Conserved Domains (3) summary
    TIGR01645
    Location:76 → 228
    half-pint; poly-U binding splicing factor, half-pint family
    cd12407
    Location:92 → 167
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:232 → 289
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

  36. XM_030248852.2 → XP_030104712.1  RNA binding protein fox-1 homolog 2 isoform X36

    Related
    ENSMUSP00000154522.2, ENSMUST00000228558.2
    Conserved Domains (2) summary
    cd12407
    Location:134 → 209
    RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
    pfam12414
    Location:274 → 318
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal

RNA

  1. XR_003951446.2 RNA Sequence

  2. XR_001781584.3 RNA Sequence

  3. XR_384057.4 RNA Sequence

  4. XR_004938883.1 RNA Sequence

  5. XR_003951448.2 RNA Sequence

  6. XR_003951450.2 RNA Sequence

  7. XR_003951449.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001358771.1: Suppressed sequence

    Description
    NM_001358771.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BP71.2 GenPept UniProtKB/Swiss-Prot:Q8BP71

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