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ATMIN ATM interactor [ Homo sapiens (human) ]

Gene ID: 23300, updated on 1-Aug-2020

Summary

Official Symbol
ATMINprovided by HGNC
Official Full Name
ATM interactorprovided by HGNC
Primary source
HGNC:HGNC:29034
See related
Ensembl:ENSG00000166454 MIM:614693
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASCIZ; ZNF822
Expression
Ubiquitous expression in testis (RPKM 24.3), brain (RPKM 16.0) and 25 other tissues See more
Orthologs

Genomic context

See ATMIN in Genome Data Viewer
Location:
16q23.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (81035842..81047350)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (81069458..81080955)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene androgen receptor regulated long noncoding RNA 1 Neighboring gene C-X9-C motif containing 2 Neighboring gene CENPN antisense RNA 1 Neighboring gene centromere protein N Neighboring gene chromosome 16 open reading frame 46 Neighboring gene uncharacterized LOC105371361 Neighboring gene glycine cleavage system protein H

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of ATM interactor (ATMIN) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ50270, FLJ61620, FLJ76795, KIAA0431, DKFZp779K1455

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription activator activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
 
dynein complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
motile cilium assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of non-motile cilium assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nuclear body IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
ATM interactor
Names
ATM INteracting protein
ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein
ATM/ATR-substrate CHEK2-interacting zinc finger protein
ATM/ATR-substrate CHK2-interacting zinc finger protein
zinc finger protein 822

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300728.2NP_001287657.1  ATM interactor isoform 2

    See identical proteins and their annotated locations for NP_001287657.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC092718
    Consensus CDS
    CCDS73917.1
    UniProtKB/Swiss-Prot
    O43313
    Related
    ENSP00000463478.1, ENST00000564241.5
  2. NM_015251.3NP_056066.2  ATM interactor isoform 1

    See identical proteins and their annotated locations for NP_056066.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AB007891, AC092718, BC002701, BI259534, BM693775, BX343387, BX375235, CF593326
    Consensus CDS
    CCDS32494.1
    UniProtKB/Swiss-Prot
    O43313
    Related
    ENSP00000299575.3, ENST00000299575.5
    Conserved Domains (1) summary
    sd00017
    Location:133160
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    81035842..81047350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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