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KANK1 KN motif and ankyrin repeat domains 1 [ Homo sapiens (human) ]

Gene ID: 23189, updated on 1-Jun-2020

Summary

Official Symbol
KANK1provided by HGNC
Official Full Name
KN motif and ankyrin repeat domains 1provided by HGNC
Primary source
HGNC:HGNC:19309
See related
Ensembl:ENSG00000107104 MIM:607704
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KANK; CPSQ2; ANKRD15
Summary
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Expression
Ubiquitous expression in esophagus (RPKM 11.7), heart (RPKM 11.6) and 24 other tissues See more
Orthologs

Genomic context

See KANK1 in Genome Data Viewer
Location:
9p24.3
Exon count:
28
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (470291..746106)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (470294..746106)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 8 Neighboring gene uncharacterized LOC105375945 Neighboring gene uncharacterized LOC112268042 Neighboring gene uncharacterized LOC105375947 Neighboring gene ribosomal protein L12 pseudogene 25 Neighboring gene family with sequence similarity 217 member A pseudogene 1 Neighboring gene RNA, U6 small nuclear 1327, pseudogene Neighboring gene phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like Neighboring gene eukaryotic translation initiation factor 1 pseudogene 1 Neighboring gene uncharacterized LOC105375949 Neighboring gene doublesex and mab-3 related transcription factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Cerebral palsy, spastic quadriplegic, 2
MedGen: C2752061 OMIM: 612900 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated (2016-04-28)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated (2016-04-28)

ClinGen Genome Curation Page

NHGRI GWAS Catalog

Description
Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.
NHGRI GWA Catalog
Genome-wide association study of lung function decline in adults with and without asthma.
NHGRI GWA Catalog
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ18161, KIAA0172, MGC43128, DKFZp451G231

Gene Ontology Provided by GOA

Function Evidence Code Pubs
beta-catenin binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
glomerular visceral epithelial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of Rho protein signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of actin filament polymerization IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of insulin receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of lamellipodium morphogenesis IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of ruffle assembly IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of substrate adhesion-dependent cell spreading IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of wound healing IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of Rho protein signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
 
ruffle membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
KN motif and ankyrin repeat domain-containing protein 1
Names
ankyrin repeat domain-containing protein 15
kidney ankyrin repeat-containing protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016331.2 RefSeqGene

    Range
    39262..280813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001256876.2NP_001243805.1  KN motif and ankyrin repeat domain-containing protein 1 isoform L

    See identical proteins and their annotated locations for NP_001243805.1

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725, AL833161, T99533
    Consensus CDS
    CCDS34976.1
    UniProtKB/Swiss-Prot
    Q14678
    Related
    ENSP00000371740.1, ENST00000382303.5
    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  2. NM_001256877.2NP_001243806.1  KN motif and ankyrin repeat domain-containing protein 1 isoform L

    See identical proteins and their annotated locations for NP_001243806.1

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, D79994, DA401115, T99533
    Consensus CDS
    CCDS34976.1
    UniProtKB/Swiss-Prot
    Q14678
    Related
    ENSP00000477725.1, ENST00000619269.4
    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_001354331.1NP_001341260.1  KN motif and ankyrin repeat domain-containing protein 1 isoform c

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725, AL833161, T99533
    Conserved Domains (5) summary
    cd00204
    Location:10761207
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:11541184
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl19580
    Location:6961103
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  4. NM_001354332.1NP_001341261.1  KN motif and ankyrin repeat domain-containing protein 1 isoform d

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725, AL833161, T99533
    Conserved Domains (4) summary
    cd00204
    Location:11381269
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12161246
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  5. NM_001354333.1NP_001341262.1  KN motif and ankyrin repeat domain-containing protein 1 isoform S

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725, AL833161, T99533
    Consensus CDS
    CCDS6441.1
    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  6. NM_001354334.1NP_001341263.1  KN motif and ankyrin repeat domain-containing protein 1 isoform L

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725, AL833161, T99533
    Consensus CDS
    CCDS34976.1
    Related
    ENSP00000501167.1, ENST00000674102.1
    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  7. NM_001354335.1NP_001341264.1  KN motif and ankyrin repeat domain-containing protein 1 isoform S

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Consensus CDS
    CCDS6441.1
    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  8. NM_001354336.1NP_001341265.1  KN motif and ankyrin repeat domain-containing protein 1 isoform e

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (4) summary
    cd00204
    Location:9001031
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:9781008
    ANK; ANK repeat [structural motif]
    cl19580
    Location:538927
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  9. NM_001354337.1NP_001341266.1  KN motif and ankyrin repeat domain-containing protein 1 isoform S

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Consensus CDS
    CCDS6441.1
    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  10. NM_001354338.1NP_001341267.1  KN motif and ankyrin repeat domain-containing protein 1 isoform f

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (3) summary
    cd00204
    Location:9801111
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10581088
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  11. NM_001354339.1NP_001341268.1  KN motif and ankyrin repeat domain-containing protein 1 isoform g

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (4) summary
    cd00204
    Location:9181049
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:9961026
    ANK; ANK repeat [structural motif]
    cl19580
    Location:538945
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  12. NM_001354340.1NP_001341269.1  KN motif and ankyrin repeat domain-containing protein 1 isoform f

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (3) summary
    cd00204
    Location:9801111
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10581088
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  13. NM_001354341.1NP_001341270.1  KN motif and ankyrin repeat domain-containing protein 1 isoform S

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Consensus CDS
    CCDS6441.1
    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  14. NM_001354342.1NP_001341271.1  KN motif and ankyrin repeat domain-containing protein 1 isoform g

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (4) summary
    cd00204
    Location:9181049
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:9961026
    ANK; ANK repeat [structural motif]
    cl19580
    Location:538945
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  15. NM_001354343.1NP_001341272.1  KN motif and ankyrin repeat domain-containing protein 1 isoform g

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (4) summary
    cd00204
    Location:9181049
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:9961026
    ANK; ANK repeat [structural motif]
    cl19580
    Location:538945
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  16. NM_001354344.1NP_001341273.1  KN motif and ankyrin repeat domain-containing protein 1 isoform f

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533
    Conserved Domains (3) summary
    cd00204
    Location:9801111
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10581088
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  17. NM_015158.5NP_055973.2  KN motif and ankyrin repeat domain-containing protein 1 isoform L

    See identical proteins and their annotated locations for NP_055973.2

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL161725
    Consensus CDS
    CCDS34976.1
    UniProtKB/Swiss-Prot
    Q14678
    Related
    ENSP00000371734.2, ENST00000382297.6
    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  18. NM_153186.5NP_694856.1  KN motif and ankyrin repeat domain-containing protein 1 isoform S

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, BC038116, T99533
    Consensus CDS
    CCDS6441.1
    UniProtKB/Swiss-Prot
    Q14678
    Related
    ENSP00000371730.3, ENST00000382293.7
    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain

RNA

  1. NR_148869.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL136979, AL833161, T99533

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    470291..746106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447461.1XP_024303229.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  2. XM_024447460.1XP_024303228.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  3. XM_024447463.1XP_024303231.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  4. XM_024447464.1XP_024303232.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  5. XM_024447465.1XP_024303233.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  6. XM_024447469.1XP_024303237.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X3

    Conserved Domains (5) summary
    cd00204
    Location:10761207
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:11541184
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl19580
    Location:6961103
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  7. XM_017014517.2XP_016870006.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X2

    Conserved Domains (4) summary
    cd00204
    Location:11381269
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12161246
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  8. XM_017014525.2XP_016870014.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X4

  9. XM_017014522.2XP_016870011.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X3

    Conserved Domains (5) summary
    cd00204
    Location:10761207
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:11541184
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl19580
    Location:6961103
    YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  10. XM_024447466.1XP_024303234.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  11. XM_024447462.1XP_024303230.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  12. XM_024447468.1XP_024303236.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  13. XM_024447467.1XP_024303235.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:11561287
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:12341264
    ANK; ANK repeat [structural motif]
    pfam12075
    Location:3068
    KN_motif; KN motif
    cl25732
    Location:264528
    SMC_N; RecF/RecN/SMC N terminal domain
  14. XM_024447470.1XP_024303238.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X5

    Conserved Domains (3) summary
    cd00204
    Location:9981129
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10761106
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain
  15. XM_024447471.1XP_024303239.1  KN motif and ankyrin repeat domain-containing protein 1 isoform X6

    Conserved Domains (3) summary
    cd00204
    Location:9801111
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10581088
    ANK; ANK repeat [structural motif]
    cl25732
    Location:106370
    SMC_N; RecF/RecN/SMC N terminal domain

RNA

  1. XR_002956771.1 RNA Sequence

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