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Amz1 archaelysin family metallopeptidase 1 [ Mus musculus (house mouse) ]

Gene ID: 231842, updated on 2-Nov-2024

Summary

Official Symbol
Amz1provided by MGI
Official Full Name
archaelysin family metallopeptidase 1provided by MGI
Primary source
MGI:MGI:2442258
See related
Ensembl:ENSMUSG00000050022 AllianceGenome:MGI:2442258
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5330426I05; 6530401C20Rik
Summary
Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis. Orthologous to human AMZ1 (archaelysin family metallopeptidase 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in spleen adult (RPKM 7.6), lung adult (RPKM 5.8) and 24 other tissues See more
Orthologs
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Genomic context

See Amz1 in Genome Data Viewer
Location:
5 G2; 5 79.27 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (140709882..140739067)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (140724127..140753312)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene IQ motif containing E Neighboring gene STARR-positive B cell enhancer ABC_E11307 Neighboring gene BRCA1-associated ATM activator 1 Neighboring gene predicted gene, 30745 Neighboring gene guanine nucleotide binding protein, alpha 12 Neighboring gene STARR-positive B cell enhancer ABC_E282 Neighboring gene predicted gene, 52831 Neighboring gene predicted gene, 30804

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Markers

Potential readthrough

Included gene: Gna12

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
archaemetzincin-1
Names
archeobacterial metalloproteinase-like 1
archeobacterial metalloproteinase-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173405.2NP_775581.1  archaemetzincin-1

    See identical proteins and their annotated locations for NP_775581.1

    Status: VALIDATED

    Source sequence(s)
    AK030521, AK078332, AK139472
    Consensus CDS
    CCDS19824.1
    UniProtKB/Swiss-Prot
    Q811F9, Q8BMM5, Q8BVF9
    UniProtKB/TrEMBL
    A1L312, Q3U2S0
    Related
    ENSMUSP00000053110.5, ENSMUST00000060918.11
    Conserved Domains (1) summary
    cd11375
    Location:95306
    Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    140709882..140739067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)