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N4BP3 NEDD4 binding protein 3 [ Homo sapiens (human) ]

Gene ID: 23138, updated on 21-Dec-2019

Summary

Official Symbol
N4BP3provided by HGNC
Official Full Name
NEDD4 binding protein 3provided by HGNC
Primary source
HGNC:HGNC:29852
See related
Ensembl:ENSG00000145911
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LZTS4
Expression
Broad expression in placenta (RPKM 5.5), esophagus (RPKM 3.2) and 20 other tissues See more
Orthologs

Genomic context

See N4BP3 in Genome Data Viewer
Location:
5q35.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (178113506..178127034)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (177540556..177553107)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr5.4886 Neighboring gene uncharacterized LOC105377754 Neighboring gene required for meiotic nuclear division 5 homolog B Neighboring gene NHP2 ribonucleoprotein Neighboring gene NAD(P)HX epimerase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0341

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015111.2NP_055926.1  NEDD4-binding protein 3

    See identical proteins and their annotated locations for NP_055926.1

    Status: VALIDATED

    Source sequence(s)
    AC136632
    Consensus CDS
    CCDS34307.1
    UniProtKB/Swiss-Prot
    O15049
    Related
    ENSP00000274605.4, ENST00000274605.6
    Conserved Domains (1) summary
    pfam06818
    Location:368525
    Fez1; Fez1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    178113506..178127034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011534473.1XP_011532775.1  NEDD4-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011532775.1

    UniProtKB/Swiss-Prot
    O15049
    Conserved Domains (1) summary
    pfam06818
    Location:368525
    Fez1; Fez1
  2. XM_011534474.1XP_011532776.1  NEDD4-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011532776.1

    UniProtKB/Swiss-Prot
    O15049
    Conserved Domains (1) summary
    pfam06818
    Location:368525
    Fez1; Fez1
  3. XM_006714834.4XP_006714897.1  NEDD4-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006714897.1

    UniProtKB/Swiss-Prot
    O15049
    Conserved Domains (1) summary
    pfam06818
    Location:368525
    Fez1; Fez1

RNA

  1. XR_941094.1 RNA Sequence

  2. XR_941093.1 RNA Sequence

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