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N4bp3 NEDD4 binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 212706, updated on 5-Feb-2023

Summary

Official Symbol
N4bp3provided by MGI
Official Full Name
NEDD4 binding protein 3provided by MGI
Primary source
MGI:MGI:2442218
See related
Ensembl:ENSMUSG00000001053 AllianceGenome:MGI:2442218
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C330016O10Rik
Summary
Predicted to act upstream of or within nervous system development. Located in cytoplasmic vesicle. Is expressed in several structures, including central nervous system; eye; gut; lung; and reproductive system. Orthologous to human N4BP3 (NEDD4 binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 10.8), ovary adult (RPKM 7.6) and 26 other tissues See more
Orthologs
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Genomic context

See N4bp3 in Genome Data Viewer
Location:
11; 11 B1.3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (51533908..51541900, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (51643081..51651073, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene 5-phosphohydroxy-L-lysine phospholyase Neighboring gene heterogeneous nuclear ribonucleoprotein A/B Neighboring gene NHP2 ribonucleoprotein Neighboring gene required for meiotic nuclear division 5 homolog B Neighboring gene RIKEN cDNA D930048N14 gene Neighboring gene predicted gene, 30058 Neighboring gene RIKEN cDNA 0610009B22 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC7136

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145974.3NP_666086.2  NEDD4-binding protein 3

    See identical proteins and their annotated locations for NP_666086.2

    Status: PROVISIONAL

    Source sequence(s)
    BC055831
    Consensus CDS
    CCDS24657.1
    UniProtKB/Swiss-Prot
    Q8C7U1, Q99J06
    Related
    ENSMUSP00000001080.10, ENSMUST00000001080.16
    Conserved Domains (2) summary
    pfam05262
    Location:256439
    Borrelia_P83; Borrelia P83/100 protein
    pfam06818
    Location:361518
    Fez1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    51533908..51541900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532766.5XP_006532829.1  NEDD4-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006532829.1

    UniProtKB/Swiss-Prot
    Q8C7U1, Q99J06
    Conserved Domains (2) summary
    pfam05262
    Location:256439
    Borrelia_P83; Borrelia P83/100 protein
    pfam06818
    Location:361518
    Fez1
  2. XM_030245757.1XP_030101617.1  NEDD4-binding protein 3 isoform X1

    UniProtKB/Swiss-Prot
    Q99J06
    Conserved Domains (2) summary
    pfam05262
    Location:256439
    Borrelia_P83; Borrelia P83/100 protein
    pfam06818
    Location:361518
    Fez1
  3. XM_006532765.5XP_006532828.1  NEDD4-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006532828.1

    UniProtKB/Swiss-Prot
    Q8C7U1, Q99J06
    Conserved Domains (2) summary
    pfam05262
    Location:256439
    Borrelia_P83; Borrelia P83/100 protein
    pfam06818
    Location:361518
    Fez1