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BAHD1 bromo adjacent homology domain containing 1 [ Homo sapiens (human) ]

Gene ID: 22893, updated on 21-Dec-2019

Summary

Official Symbol
BAHD1provided by HGNC
Official Full Name
bromo adjacent homology domain containing 1provided by HGNC
Primary source
HGNC:HGNC:29153
See related
Ensembl:ENSG00000140320 MIM:613880
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 12.0), ovary (RPKM 8.8) and 25 other tissues See more
Orthologs

Genomic context

See BAHD1 in Genome Data Viewer
Location:
15q15.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (40439757..40468237)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40733411..40760441)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene kinetochore localized astrin (SPAG5) binding protein Neighboring gene isovaleryl-CoA dehydrogenase Neighboring gene carbohydrate sulfotransferase 14 Neighboring gene ribosomal protein L9 pseudogene 27

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of bromo adjacent homology domain containing 1 (BAHD1) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0945

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
heterochromatin assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
chromatin silencing complex IDA
Inferred from Direct Assay
more info
PubMed 
chromosome IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
bromo adjacent homology domain-containing 1 protein
Names
BAH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001301132.2NP_001288061.1  bromo adjacent homology domain-containing 1 protein isoform b

    See identical proteins and their annotated locations for NP_001288061.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a.
    Source sequence(s)
    AB023162, AC013356, BU740533
    Consensus CDS
    CCDS73705.1
    UniProtKB/Swiss-Prot
    Q8TBE0
    Related
    ENSP00000454150.1, ENST00000561234.5
    Conserved Domains (2) summary
    cd04714
    Location:622732
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl26464
    Location:170552
    Atrophin-1; Atrophin-1 family
  2. NM_014952.5NP_055767.3  bromo adjacent homology domain-containing 1 protein isoform a

    See identical proteins and their annotated locations for NP_055767.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AB023162, AC013356, BC022782, BU740533, HY041603
    Consensus CDS
    CCDS10058.1
    UniProtKB/Swiss-Prot
    Q8TBE0
    UniProtKB/TrEMBL
    A0A024R9K2
    Related
    ENSP00000396976.1, ENST00000416165.6
    Conserved Domains (1) summary
    cd04714
    Location:623733
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...

RNA

  1. NR_125372.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons in the central region and uses an alternate splice site in the 3' region, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AC013356, BC022782, BU740533, HY041603, HY353002

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    40439757..40468237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011521369.3XP_011519671.1  bromo adjacent homology domain-containing 1 protein isoform X4

    See identical proteins and their annotated locations for XP_011519671.1

    UniProtKB/Swiss-Prot
    Q8TBE0
    UniProtKB/TrEMBL
    A0A024R9K2
    Related
    ENSP00000454101.1, ENST00000560846.1
    Conserved Domains (1) summary
    cd04714
    Location:623733
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
  2. XM_011521367.3XP_011519669.2  bromo adjacent homology domain-containing 1 protein isoform X2

  3. XM_011521366.2XP_011519668.2  bromo adjacent homology domain-containing 1 protein isoform X1

  4. XM_011521368.2XP_011519670.2  bromo adjacent homology domain-containing 1 protein isoform X3

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