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FOXJ3 forkhead box J3 [ Homo sapiens (human) ]

Gene ID: 22887, updated on 13-Mar-2020

Summary

Official Symbol
FOXJ3provided by HGNC
Official Full Name
forkhead box J3provided by HGNC
Primary source
HGNC:HGNC:29178
See related
Ensembl:ENSG00000198815 MIM:616035
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 10.6), testis (RPKM 10.1) and 25 other tissues See more
Orthologs

Genomic context

See FOXJ3 in Genome Data Viewer
Location:
1p34.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (42176539..42336805, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (42642210..42801548, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene guanylate cyclase activator 2B Neighboring gene guanylate cyclase activator 2A Neighboring gene ribosomal modification protein rimK like family member A Neighboring gene ribosomal protein S15a pseudogene 8 Neighboring gene zinc finger MYND-type containing 12 Neighboring gene coiled-coil domain containing 30

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC165036, MGC176686

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198850.2NP_001185779.1  forkhead box protein J3 isoform 1

    See identical proteins and their annotated locations for NP_001185779.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1).
    Source sequence(s)
    AC096540, AK027075, BC063298, BC151828
    Consensus CDS
    CCDS30689.1
    UniProtKB/Swiss-Prot
    Q9UPW0
    Related
    ENSP00000361654.1, ENST00000372573.5
    Conserved Domains (2) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
    pfam15258
    Location:339445
    FAM222A; Protein family of FAM222A
  2. NM_001198851.2NP_001185780.1  forkhead box protein J3 isoform 1

    See identical proteins and their annotated locations for NP_001185780.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has two additional exons in the 5' UTR, as compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1).
    Source sequence(s)
    AK027075, BC063298, BC151828, BC152441
    Consensus CDS
    CCDS30689.1
    UniProtKB/Swiss-Prot
    Q9UPW0
    Related
    ENSP00000361653.1, ENST00000372572.5
    Conserved Domains (2) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
    pfam15258
    Location:339445
    FAM222A; Protein family of FAM222A
  3. NM_001198852.1NP_001185781.1  forkhead box protein J3 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an in-frame coding exon, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1.
    Source sequence(s)
    AB028964, AK027075, BC014182, BC063298, BC151828
    Consensus CDS
    CCDS55594.1
    UniProtKB/Swiss-Prot
    Q9UPW0
    Related
    ENSP00000354449.1, ENST00000361776.5
    Conserved Domains (1) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
  4. NM_014947.5NP_055762.3  forkhead box protein J3 isoform 1

    See identical proteins and their annotated locations for NP_055762.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variants 2 and 3 encode the same isoform (1).
    Source sequence(s)
    AC096540, AK027075, BC063298, BC151828
    Consensus CDS
    CCDS30689.1
    UniProtKB/Swiss-Prot
    Q9UPW0
    Related
    ENSP00000354620.1, ENST00000361346.6
    Conserved Domains (2) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
    pfam15258
    Location:339445
    FAM222A; Protein family of FAM222A

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    42176539..42336805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017000693.2XP_016856182.1  forkhead box protein J3 isoform X5

  2. XM_006710459.3XP_006710522.1  forkhead box protein J3 isoform X4

    Conserved Domains (1) summary
    pfam00250
    Location:86163
    Forkhead; Forkhead domain
  3. XM_005270632.4XP_005270689.1  forkhead box protein J3 isoform X1

    Conserved Domains (1) summary
    pfam00250
    Location:86163
    Forkhead; Forkhead domain
  4. XM_017000694.1XP_016856183.1  forkhead box protein J3 isoform X6

  5. XM_024454163.1XP_024309931.1  forkhead box protein J3 isoform X2

    Conserved Domains (2) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
    pfam15258
    Location:339445
    FAM222A; Protein family of FAM222A
  6. XM_006710458.4XP_006710521.1  forkhead box protein J3 isoform X3

    Conserved Domains (1) summary
    pfam00250
    Location:63140
    Forkhead; Forkhead domain
  7. XM_011541026.2XP_011539328.1  forkhead box protein J3 isoform X2

    See identical proteins and their annotated locations for XP_011539328.1

    UniProtKB/Swiss-Prot
    Q9UPW0
    Conserved Domains (2) summary
    pfam00250
    Location:78155
    Forkhead; Forkhead domain
    pfam15258
    Location:339445
    FAM222A; Protein family of FAM222A
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