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Zik1 zinc finger protein interacting with K protein 1 [ Mus musculus (house mouse) ]

Gene ID: 22775, updated on 11-Apr-2024

Summary

Official Symbol
Zik1provided by MGI
Official Full Name
zinc finger protein interacting with K protein 1provided by MGI
Primary source
MGI:MGI:108070
See related
Ensembl:ENSMUSG00000030393 AllianceGenome:MGI:108070
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; peripheral nervous system; and retina. Orthologous to human ZIK1 (zinc finger protein interacting with K protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 9.0), CNS E14 (RPKM 8.3) and 11 other tissues See more
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Genomic context

See Zik1 in Genome Data Viewer
Location:
7 A1; 7 6.47 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (10221151..10229308, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (10487224..10495381, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 67 Neighboring gene STARR-seq mESC enhancer starr_18012 Neighboring gene predicted gene, 30645 Neighboring gene zinc finger protein 623 pseudogene Neighboring gene vomeronasal 1 receptor 68

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger protein interacting with ribonucleoprotein K

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009577.3NP_033603.2  zinc finger protein interacting with ribonucleoprotein K

    See identical proteins and their annotated locations for NP_033603.2

    Status: VALIDATED

    Source sequence(s)
    AC159008, BC050942, BY026558
    Consensus CDS
    CCDS20792.1
    UniProtKB/Swiss-Prot
    P70405, Q80YP6
    Related
    ENSMUSP00000032551.8, ENSMUST00000032551.8
    Conserved Domains (4) summary
    COG5048
    Location:112425
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:357377
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1452
    KRAB; KRAB box
    pfam13465
    Location:342366
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    10221151..10229308 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)