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Plagl1 pleiomorphic adenoma gene-like 1 [ Mus musculus (house mouse) ]

Gene ID: 22634, updated on 31-Jan-2019

Summary

Official Symbol
Plagl1provided by MGI
Official Full Name
pleiomorphic adenoma gene-like 1provided by MGI
Primary source
MGI:MGI:1100874
See related
Ensembl:ENSMUSG00000019817
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lot1; Zac1; 2610311E24Rik
Expression
Biased expression in limb E14.5 (RPKM 270.7), CNS E11.5 (RPKM 64.6) and 8 other tissues See more
Orthologs

Genomic context

See Plagl1 in Genome Data Viewer
Location:
10 A2; 10 4.72 cM
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (13090788..13131694)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (12810594..12851500)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene splicing factor 3b, subunit 5 Neighboring gene predicted gene, 40602 Neighboring gene hydatidiform mole associated and imprinted transcript Neighboring gene zinc finger, C2HC-type containing 1B Neighboring gene LTV1 ribosome biogenesis factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of gene expression IGI
Inferred from Genetic Interaction
more info
PubMed 
skeletal muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nuclear body ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger protein PLAGL1
Names
zinc finger protein regulator of apoptosis and cell cycle arrest

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364643.1NP_001351572.1  zinc finger protein PLAGL1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AK142052, AK142210, BC065150
    Conserved Domains (3) summary
    COG5189
    Location:29109
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:4973
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001364644.1NP_001351573.1  zinc finger protein PLAGL1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AK142052, AK142210, BC065150
    Conserved Domains (3) summary
    COG5189
    Location:29109
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:4973
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001364645.1NP_001351574.1  zinc finger protein PLAGL1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL691505, AL713985
    Conserved Domains (3) summary
    COG5189
    Location:29109
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:4973
    zf-H2C2_2; Zinc-finger double domain
  4. NM_009538.3NP_033564.2  zinc finger protein PLAGL1 isoform a

    See identical proteins and their annotated locations for NP_033564.2

    Status: VALIDATED

    Source sequence(s)
    BC065150
    Consensus CDS
    CCDS48501.1
    UniProtKB/TrEMBL
    Q9JLQ4
    Related
    ENSMUSP00000112847.1, ENSMUST00000121646.7
    Conserved Domains (2) summary
    sd00017
    Location:626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:4973
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

    Range
    13090788..13131694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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