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ZNF438 zinc finger protein 438 [ Homo sapiens (human) ]

Gene ID: 220929, updated on 2-Nov-2024

Summary

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Official Symbol
ZNF438provided by HGNC
Official Full Name
zinc finger protein 438provided by HGNC
Primary source
HGNC:HGNC:21029
See related
Ensembl:ENSG00000183621 MIM:620749; AllianceGenome:HGNC:21029
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
bA330O11.1
Summary
Enables DNA-binding transcription factor activity. Involved in negative regulation of DNA-templated transcription. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in thyroid (RPKM 2.5), testis (RPKM 2.0) and 24 other tissues See more
Orthologs
mouse all
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Genomic context

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See ZNF438 in Genome Data Viewer
Location:
10p11.23
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (30844632..31032411, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (30875934..31063684, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (31133561..31320794, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3225 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3226 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3227 Neighboring gene long intergenic non-protein coding RNA 2644 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3228 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2268 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2269 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31072075-31072575 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2270 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31106665-31107586 Neighboring gene uncharacterized LOC124902405 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31135691-31136191 Neighboring gene MPRA-validated peak916 silencer Neighboring gene DEAD-box helicase 10 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3230 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3231 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2271 Neighboring gene uncharacterized LOC105376481 Neighboring gene MPRA-validated peak918 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3233 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3234 Neighboring gene uncharacterized LOC105376482 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2272 Neighboring gene uncharacterized LOC105376483 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2273 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31435102-31435653 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31435654-31436204 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3235 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:31498085-31498585 Neighboring gene long intergenic non-protein coding RNA 2664 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:31531588-31532787 Neighboring gene RNA, 5S ribosomal pseudogene 309

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity. Zhong Z, et al. J Biochem Mol Biol, 2007 Jul 31. PMID 17669267
  2. Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations. Mitchell LE, et al. Hum Mol Genet, 2015 Jan 1. PMID 25138779, Free PMC Article
  3. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. International Multiple Sclerosis Genetics Consortium, et al. Nature, 2011 Aug 10. PMID 21833088, Free PMC Article
  4. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Okada Y, et al. Nature, 2014 Feb 20. PMID 24390342, Free PMC Article
  5. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. He M, et al. Hum Mol Genet, 2015 Mar 15. PMID 25429064, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  2. Observational study of gene-disease association. (HuGE Navigator)
    Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
  3. The transcriptional activity of ZNF438 was studied by transfecting recombinant pM-ZNF438 into mammalian cells. The subsequent analysis based on the duel luciferase assay system showed that ZNF438 was a transcriptional repressor.
    Title: Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
EBI GWAS Catalog
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
EBI GWAS Catalog
Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ32761, MGC126671

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
zinc finger protein 438

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143766.2 → NP_001137238.1  zinc finger protein 438 isoform a

    See identical proteins and their annotated locations for NP_001137238.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1-4 encode the same isoform.
    Source sequence(s)
    AF428258, AI703004, AK292730, AL359532, DA513699
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  2. NM_001143767.2 → NP_001137239.1  zinc finger protein 438 isoform a

    See identical proteins and their annotated locations for NP_001137239.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    AF428258, AI703004, AL359532, DA402463
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Related
    ENSP00000387546.1, ENST00000413025.5
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  3. NM_001143768.2 → NP_001137240.1  zinc finger protein 438 isoform a

    See identical proteins and their annotated locations for NP_001137240.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    AF428258, AI703004, AL359532, DA479799
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Related
    ENSP00000406934.2, ENST00000436087.7
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  4. NM_001143769.2 → NP_001137241.1  zinc finger protein 438 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has multiple differences in the 5' UTR, which results in the primary ORF beginning at a downstream start codon, compared to variant 1. The resulting protein (isoform c) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AF428258, AI703004, AK131357, AL359532, AL596113
    Consensus CDS
    CCDS53504.1
    UniProtKB/Swiss-Prot
    Q7Z4V0
    Related
    ENSP00000445461.1, ENST00000538351.6
    Conserved Domains (3) summary
    sd00017
    Location:460 → 480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:472 → 497
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:49 → 315
    Atrophin-1; Atrophin-1 family

  5. NM_001143770.2 → NP_001137242.1  zinc finger protein 438 isoform b

    See identical proteins and their annotated locations for NP_001137242.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and includes an additional exon in the 5' coding region which results in the primary ORF beginning at a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus, compared to isoform a. Both variants 6 and 7 encode the same isoform.
    Source sequence(s)
    AI703004, AL359532, DA513699, DQ356011
    Consensus CDS
    CCDS44369.1
    UniProtKB/Swiss-Prot
    Q7Z4V0
    Related
    ENSP00000413060.1, ENST00000452305.5
    Conserved Domains (2) summary
    sd00017
    Location:499 → 519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:511 → 536
    zf-H2C2_2; Zinc-finger double domain

  6. NM_001143771.2 → NP_001137243.1  zinc finger protein 438 isoform b

    See identical proteins and their annotated locations for NP_001137243.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and includes an additional exon in the 5' coding region which results in the primary ORF beginning at a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus, compared to isoform a. Both variants 6 and 7 encode the same isoform.
    Source sequence(s)
    AI703004, AL359532, DA513699, DQ356012
    Consensus CDS
    CCDS44369.1
    UniProtKB/Swiss-Prot
    Q7Z4V0
    Conserved Domains (2) summary
    sd00017
    Location:499 → 519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:511 → 536
    zf-H2C2_2; Zinc-finger double domain

  7. NM_001387405.1 → NP_001374334.1  zinc finger protein 438 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL359532, AL596113
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  8. NM_001387411.1 → NP_001374340.1  zinc finger protein 438 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL359532, AL359546
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  9. NM_001387412.1 → NP_001374341.1  zinc finger protein 438 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL359532, AL359546, AL596113
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  10. NM_182755.3 → NP_877432.1  zinc finger protein 438 isoform a

    See identical proteins and their annotated locations for NP_877432.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same isoform (a).
    Source sequence(s)
    AF428258, AI703004, AL359532, DA513699
    Consensus CDS
    CCDS7168.1
    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Related
    ENSP00000412363.1, ENST00000442986.5
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

RNA

  1. NR_026560.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and has an alternate splice pattern in the coding region, compared to variant 1. It is represented as non-coding because it lacks a large portion of the coding region found in variant 1.
    Source sequence(s)
    AF428258, AI703004, AK057323, AL359532

  2. NR_170659.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL359532, AL359546

  3. NR_170660.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL359532, AL359546

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    30844632..31032411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424729.1 → XP_047280685.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  2. XM_024447871.2 → XP_024303639.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  3. XM_011519372.3 → XP_011517674.1  zinc finger protein 438 isoform X2

    See identical proteins and their annotated locations for XP_011517674.1

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  4. XM_047424739.1 → XP_047280695.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  5. XM_047424733.1 → XP_047280689.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  6. XM_047424746.1 → XP_047280702.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  7. XM_047424741.1 → XP_047280697.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  8. XM_024447872.2 → XP_024303640.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  9. XM_024447873.2 → XP_024303641.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  10. XM_047424734.1 → XP_047280690.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  11. XM_047424737.1 → XP_047280693.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  12. XM_006717399.4 → XP_006717462.1  zinc finger protein 438 isoform X3

    See identical proteins and their annotated locations for XP_006717462.1

    UniProtKB/Swiss-Prot
    Q7Z4V0
    Conserved Domains (2) summary
    sd00017
    Location:499 → 519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:511 → 536
    zf-H2C2_2; Zinc-finger double domain

  13. XM_011519377.3 → XP_011517679.1  zinc finger protein 438 isoform X3

    See identical proteins and their annotated locations for XP_011517679.1

    UniProtKB/Swiss-Prot
    Q7Z4V0
    Conserved Domains (2) summary
    sd00017
    Location:499 → 519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:511 → 536
    zf-H2C2_2; Zinc-finger double domain

  14. XM_017015877.2 → XP_016871366.1  zinc finger protein 438 isoform X5

    UniProtKB/TrEMBL
    B3KQ40, Q5T427, Q7Z4T7
    Related
    ENSP00000364460.1, ENST00000375311.1
    Conserved Domains (2) summary
    COG5048
    Location:47 → 126
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:73 → 93
    ZF_C2H2; C2H2 Zn finger [structural motif]

  15. XM_047424750.1 → XP_047280706.1  zinc finger protein 438 isoform X4

  16. XM_011519376.3 → XP_011517678.1  zinc finger protein 438 isoform X3

    See identical proteins and their annotated locations for XP_011517678.1

    UniProtKB/Swiss-Prot
    Q7Z4V0
    Conserved Domains (2) summary
    sd00017
    Location:499 → 519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:511 → 536
    zf-H2C2_2; Zinc-finger double domain

  17. XM_047424724.1 → XP_047280680.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  18. XM_024447868.2 → XP_024303636.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  19. XM_047424728.1 → XP_047280684.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  20. XM_047424748.1 → XP_047280704.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  21. XM_047424738.1 → XP_047280694.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  22. XM_047424740.1 → XP_047280696.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  23. XM_024447870.2 → XP_024303638.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  24. XM_047424731.1 → XP_047280687.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  25. XM_047424730.1 → XP_047280686.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  26. XM_047424744.1 → XP_047280700.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  27. XM_047424749.1 → XP_047280705.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  28. XM_047424742.1 → XP_047280698.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  29. XM_047424745.1 → XP_047280701.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  30. XM_017015870.3 → XP_016871359.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  31. XM_011519373.4 → XP_011517675.1  zinc finger protein 438 isoform X2

    See identical proteins and their annotated locations for XP_011517675.1

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  32. XM_047424736.1 → XP_047280692.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  33. XM_047424735.1 → XP_047280691.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  34. XM_017015869.3 → XP_016871358.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  35. XM_047424725.1 → XP_047280681.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  36. XM_047424726.1 → XP_047280682.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  37. XM_047424732.1 → XP_047280688.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  38. XM_047424727.1 → XP_047280683.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  39. XM_024447869.2 → XP_024303637.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  40. XM_047424723.1 → XP_047280679.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  41. XM_047424747.1 → XP_047280703.1  zinc finger protein 438 isoform X2

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0

  42. XM_011519374.3 → XP_011517676.1  zinc finger protein 438 isoform X2

    See identical proteins and their annotated locations for XP_011517676.1

    UniProtKB/Swiss-Prot
    A2A3J4, A8K9L5, Q5T426, Q658Q4, Q6ZN65, Q7Z4V0
    Conserved Domains (4) summary
    PHA03247
    Location:98 → 364
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:509 → 529
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:507 → 529
    zf-C2H2; Zinc finger, C2H2 type
    pfam13894
    Location:535 → 558
    zf-C2H2_4; C2H2-type zinc finger

  43. XM_017015863.3 → XP_016871352.1  zinc finger protein 438 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    30875934..31063684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054365047.1 → XP_054221022.1  zinc finger protein 438 isoform X2

  2. XM_054365044.1 → XP_054221019.1  zinc finger protein 438 isoform X2

  3. XM_054365035.1 → XP_054221010.1  zinc finger protein 438 isoform X2

  4. XM_054365060.1 → XP_054221035.1  zinc finger protein 438 isoform X2

  5. XM_054365052.1 → XP_054221027.1  zinc finger protein 438 isoform X2

  6. XM_054365067.1 → XP_054221042.1  zinc finger protein 438 isoform X2

  7. XM_054365065.1 → XP_054221040.1  zinc finger protein 438 isoform X2

  8. XM_054365049.1 → XP_054221024.1  zinc finger protein 438 isoform X2

  9. XM_054365054.1 → XP_054221029.1  zinc finger protein 438 isoform X2

  10. XM_054365053.1 → XP_054221028.1  zinc finger protein 438 isoform X2

  11. XM_054365057.1 → XP_054221032.1  zinc finger protein 438 isoform X2

  12. XM_054365071.1 → XP_054221046.1  zinc finger protein 438 isoform X3

  13. XM_054365072.1 → XP_054221047.1  zinc finger protein 438 isoform X3

  14. XM_054365074.1 → XP_054221049.1  zinc finger protein 438 isoform X5

    UniProtKB/TrEMBL
    Q5T427

  15. XM_054365073.1 → XP_054221048.1  zinc finger protein 438 isoform X4

  16. XM_054365070.1 → XP_054221045.1  zinc finger protein 438 isoform X3

  17. XM_054365038.1 → XP_054221013.1  zinc finger protein 438 isoform X2

  18. XM_054365034.1 → XP_054221009.1  zinc finger protein 438 isoform X2

  19. XM_054365046.1 → XP_054221021.1  zinc finger protein 438 isoform X2

  20. XM_054365068.1 → XP_054221043.1  zinc finger protein 438 isoform X2

  21. XM_054365059.1 → XP_054221034.1  zinc finger protein 438 isoform X2

  22. XM_054365062.1 → XP_054221037.1  zinc finger protein 438 isoform X2

  23. XM_054365037.1 → XP_054221012.1  zinc finger protein 438 isoform X2

  24. XM_054365050.1 → XP_054221025.1  zinc finger protein 438 isoform X2

  25. XM_054365048.1 → XP_054221023.1  zinc finger protein 438 isoform X2

  26. XM_054365066.1 → XP_054221041.1  zinc finger protein 438 isoform X2

  27. XM_054365069.1 → XP_054221044.1  zinc finger protein 438 isoform X2

  28. XM_054365063.1 → XP_054221038.1  zinc finger protein 438 isoform X2

  29. XM_054365041.1 → XP_054221016.1  zinc finger protein 438 isoform X2

  30. XM_054365058.1 → XP_054221033.1  zinc finger protein 438 isoform X2

  31. XM_054365045.1 → XP_054221020.1  zinc finger protein 438 isoform X2

  32. XM_054365056.1 → XP_054221031.1  zinc finger protein 438 isoform X2

  33. XM_054365055.1 → XP_054221030.1  zinc finger protein 438 isoform X2

  34. XM_054365061.1 → XP_054221036.1  zinc finger protein 438 isoform X2

  35. XM_054365039.1 → XP_054221014.1  zinc finger protein 438 isoform X2

  36. XM_054365042.1 → XP_054221017.1  zinc finger protein 438 isoform X2

  37. XM_054365051.1 → XP_054221026.1  zinc finger protein 438 isoform X2

  38. XM_054365043.1 → XP_054221018.1  zinc finger protein 438 isoform X2

  39. XM_054365040.1 → XP_054221015.1  zinc finger protein 438 isoform X2

  40. XM_054365036.1 → XP_054221011.1  zinc finger protein 438 isoform X2

  41. XM_054365064.1 → XP_054221039.1  zinc finger protein 438 isoform X2

  42. XM_054365033.1 → XP_054221008.1  zinc finger protein 438 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7Z4V0.1 GenPept UniProtKB/Swiss-Prot:Q7Z4V0

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