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Psmb5 proteasome (prosome, macropain) subunit, beta type 5 [ Mus musculus (house mouse) ]

Gene ID: 19173, updated on 8-Jul-2018
Official Symbol
Psmb5provided by MGI
Official Full Name
proteasome (prosome, macropain) subunit, beta type 5provided by MGI
Primary source
MGI:MGI:1194513
See related
Ensembl:ENSMUSG00000022193
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in adrenal adult (RPKM 108.4), ovary adult (RPKM 85.6) and 28 other tissues See more
Orthologs
See Psmb5 in Genome Data Viewer
Location:
14 C2; 14 27.86 cM
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (54614120..54617995, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55232957..55236832, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene ajuba LIM protein Neighboring gene RIKEN cDNA 4931414P19 gene Neighboring gene microRNA 686 Neighboring gene proteasome (prosome, macropain) subunit, beta type, 11 Neighboring gene cadherin-like 24

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC118075

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
peptidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
proteolysis ISO
Inferred from Sequence Orthology
more info
PubMed 
proteolysis involved in cellular protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
response to oxidative stress IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
proteasome subunit beta type-5
Names
macropain epsilon chain
multicatalytic endopeptidase complex epsilon chain
proteasome beta type subunit 5
proteasome chain 6
proteasome epsilon chain
proteasome subunit X
NP_035316.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011186.1NP_035316.1  proteasome subunit beta type-5

    See identical proteins and their annotated locations for NP_035316.1

    Status: VALIDATED

    Source sequence(s)
    AF060091
    Consensus CDS
    CCDS27095.1
    UniProtKB/Swiss-Prot
    O55234
    Related
    ENSMUSP00000022803.4, ENSMUST00000022803.5
    Conserved Domains (1) summary
    cd03761
    Location:60247
    proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    54614120..54617995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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