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Pparg peroxisome proliferator activated receptor gamma [ Mus musculus (house mouse) ]

Gene ID: 19016, updated on 19-Jun-2018
Official Symbol
Ppargprovided by MGI
Official Full Name
peroxisome proliferator activated receptor gammaprovided by MGI
Primary source
MGI:MGI:97747
See related
Ensembl:ENSMUSG00000000440 Vega:OTTMUSG00000056643
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nr1c3; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2
Summary
This gene encodes a nuclear receptor protein belonging to the peroxisome proliferator-activated receptor (Ppar) family. The encoded protein is a ligand-activated transcription factor that is involved in the regulation of adipocyte differentiation and glucose homeostasis. The encoded protein forms a heterodimer with retinoid X receptors and binds to DNA motifs termed "peroxisome proliferator response elements" to either activate or inhibit gene expression. Mice lacking the encoded protein die at an embryonic stage due to severe defects in placental vascularization. When the embryos lacking this gene are supplemented with healthy placentas, the mutants survive to term, but succumb to lipodystrophy and multiple hemorrhages. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Expression
Biased expression in subcutaneous fat pad adult (RPKM 32.5), mammary gland adult (RPKM 26.1) and 13 other tissues See more
Orthologs
See Pparg in Genome Data Viewer
Location:
6 E3; 6 53.41 cM
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (115360877..115490404)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (115311239..115440419)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 38877 Neighboring gene predicted gene, 38878 Neighboring gene predicted gene, 36301 Neighboring gene predicted gene, 36355

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DBD domain binding ISO
Inferred from Sequence Orthology
more info
 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
CONTRIBUTES_TO DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
E-box binding IDA
Inferred from Direct Assay
more info
PubMed 
LBD domain binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II repressing transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
WW domain binding ISO
Inferred from Sequence Orthology
more info
PubMed 
activating transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
alpha-actinin binding ISO
Inferred from Sequence Orthology
more info
 
arachidonic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
drug binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
drug binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
estrogen receptor binding ISO
Inferred from Sequence Orthology
more info
 
fatty acid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear receptor activity ISO
Inferred from Sequence Orthology
more info
 
nuclear receptor activity TAS
Traceable Author Statement
more info
PubMed 
nuclear receptor transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear receptor transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
peptide binding ISO
Inferred from Sequence Orthology
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
protein self-association ISO
Inferred from Sequence Orthology
more info
 
retinoid X receptor binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, RNA polymerase II transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
brown fat cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell maturation ISO
Inferred from Sequence Orthology
more info
 
cellular response to insulin stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to insulin stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to insulin stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to lipid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to lithium ion IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to low-density lipoprotein particle stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to organic cyclic compound IDA
Inferred from Direct Assay
more info
PubMed 
diet induced thermogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
fat cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
fat cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
fat cell differentiation IPI
Inferred from Physical Interaction
more info
PubMed 
fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
fatty acid oxidation ISO
Inferred from Sequence Orthology
more info
 
glucose homeostasis ISO
Inferred from Sequence Orthology
more info
 
hormone-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inflammatory response TAS
Traceable Author Statement
more info
PubMed 
lipoprotein transport ISO
Inferred from Sequence Orthology
more info
 
long-chain fatty acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
low-density lipoprotein particle receptor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
macrophage derived foam cell differentiation ISO
Inferred from Sequence Orthology
more info
 
monocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of acute inflammatory response ISO
Inferred from Sequence Orthology
more info
 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cellular response to insulin stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cholesterol storage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of cholesterol storage ISO
Inferred from Sequence Orthology
more info
 
negative regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cytokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of gene silencing by miRNA ISO
Inferred from Sequence Orthology
more info
 
negative regulation of inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of interferon-gamma-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of macrophage derived foam cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of pancreatic stellate cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of peptide hormone secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of receptor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of sequestering of triglyceride ISO
Inferred from Sequence Orthology
more info
 
negative regulation of smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of telomerase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of vascular endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of vascular smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
peroxisome proliferator activated receptor signaling pathway IPI
Inferred from Physical Interaction
more info
PubMed 
peroxisome proliferator activated receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA binding ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of fat cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of fat cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of fat cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of fatty acid oxidation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of oligodendrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phagocytosis, engulfment ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vascular associated smooth muscle cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
pri-miRNA transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of blood pressure ISO
Inferred from Sequence Orthology
more info
 
regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of fat cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of fat cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of lipid metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription involved in cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to dietary excess IDA
Inferred from Direct Assay
more info
PubMed 
response to food IDA
Inferred from Direct Assay
more info
PubMed 
response to light stimulus IDA
Inferred from Direct Assay
more info
PubMed 
response to lipid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to lipid IDA
Inferred from Direct Assay
more info
PubMed 
response to nutrient levels IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to retinoic acid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to retinoic acid IDA
Inferred from Direct Assay
more info
PubMed 
response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
white fat cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
white fat cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
peroxisome proliferator-activated receptor gamma
Names
nuclear receptor subfamily 1 group C member 3
peroxisome proliferator activated receptor gamma 2
peroxisome proliferator activated receptor gamma 4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127330.2NP_001120802.1  peroxisome proliferator-activated receptor gamma isoform 1

    See identical proteins and their annotated locations for NP_001120802.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) contains alternate exons in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 2. The encoded isoform (1) has a distinct N-terminus and is shorter than isoform 2. Variants 1, 3 and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AB644275, AC171970, CN701591, U10374
    Consensus CDS
    CCDS51876.1
    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Related
    ENSMUSP00000131962.1, OTTMUSP00000073337, ENSMUST00000171644.7, OTTMUST00000139811
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region
  2. NM_001308352.1NP_001295281.1  peroxisome proliferator-activated receptor gamma isoform 1

    See identical proteins and their annotated locations for NP_001295281.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains alternate exons in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 2. The encoded isoform (1) has a distinct N-terminus and is shorter than isoform 2. Variants 1, 3 and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AB644275, AC171970, CN701591, U10374
    Consensus CDS
    CCDS51876.1
    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region
  3. NM_001308354.1NP_001295283.1  peroxisome proliferator-activated receptor gamma isoform 1

    See identical proteins and their annotated locations for NP_001295283.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) contains alternate exons in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 2. The encoded isoform (1) has a distinct N-terminus and is shorter than isoform 2. Variants 1, 3 and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AB644275, CJ043379
    Consensus CDS
    CCDS51876.1
    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Related
    ENSMUSP00000145525.1, OTTMUSP00000073338, ENSMUST00000203732.2, OTTMUST00000139813
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region
  4. NM_011146.3NP_035276.2  peroxisome proliferator-activated receptor gamma isoform 2

    See identical proteins and their annotated locations for NP_035276.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) encodes the longer isoform (2).
    Source sequence(s)
    AB644275, AC171970, U10374
    Consensus CDS
    CCDS20439.1
    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1, Q6GU14
    Related
    ENSMUSP00000000450.3, OTTMUSP00000073339, ENSMUST00000000450.4, OTTMUST00000139814
    Conserved Domains (3) summary
    cd06932
    Location:237504
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:138221
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:31108
    PPARgamma_N; PPAR gamma N-terminal region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    115360877..115490404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505743.3XP_006505806.1  peroxisome proliferator-activated receptor gamma isoform X2

    See identical proteins and their annotated locations for XP_006505806.1

    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region
  2. XM_006505737.3XP_006505800.1  peroxisome proliferator-activated receptor gamma isoform X1

    See identical proteins and their annotated locations for XP_006505800.1

    Conserved Domains (3) summary
    cd06932
    Location:232499
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:133216
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:26103
    PPARgamma_N; PPAR gamma N-terminal region
  3. XM_006505739.2XP_006505802.1  peroxisome proliferator-activated receptor gamma isoform X1

    See identical proteins and their annotated locations for XP_006505802.1

    Conserved Domains (3) summary
    cd06932
    Location:232499
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:133216
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:26103
    PPARgamma_N; PPAR gamma N-terminal region
  4. XM_017321455.1XP_017176944.1  peroxisome proliferator-activated receptor gamma isoform X2

    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region
  5. XM_017321456.1XP_017176945.1  peroxisome proliferator-activated receptor gamma isoform X3

    Conserved Domains (1) summary
    cd06932
    Location:25292
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
  6. XM_006505738.3XP_006505801.1  peroxisome proliferator-activated receptor gamma isoform X1

    See identical proteins and their annotated locations for XP_006505801.1

    Conserved Domains (3) summary
    cd06932
    Location:232499
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:133216
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:26103
    PPARgamma_N; PPAR gamma N-terminal region
  7. XM_011241252.1XP_011239554.1  peroxisome proliferator-activated receptor gamma isoform X2

    See identical proteins and their annotated locations for XP_011239554.1

    UniProtKB/Swiss-Prot
    P37238
    UniProtKB/TrEMBL
    M1VPI1
    Conserved Domains (3) summary
    cd06932
    Location:207474
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:108191
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    pfam12577
    Location:178
    PPARgamma_N; PPAR gamma N-terminal region

RNA

  1. XR_001785108.1 RNA Sequence

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