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Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 [ Mus musculus (house mouse) ]

Gene ID: 18674, updated on 8-Feb-2024

Summary

Official Symbol
Slc25a3provided by MGI
Official Full Name
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3provided by MGI
Primary source
MGI:MGI:1353498
See related
Ensembl:ENSMUSG00000061904 AllianceGenome:MGI:1353498
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PTP; Phc; 5730556H19Rik
Summary
Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Located in mitochondrial inner membrane and myelin sheath. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SLC25A3 (solute carrier family 25 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 904.7), duodenum adult (RPKM 787.5) and 28 other tissues See more
Orthologs
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Genomic context

See Slc25a3 in Genome Data Viewer
Location:
10 C2; 10 45.6 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (90952436..90959902, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (91116574..91124046, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27538 Neighboring gene apoptotic peptidase activating factor 1 Neighboring gene predicted gene, 25390 Neighboring gene STARR-positive B cell enhancer ABC_E9131 Neighboring gene IKBKB interacting protein Neighboring gene STARR-positive B cell enhancer ABC_E370 Neighboring gene predicted gene, 24119 Neighboring gene STARR-positive B cell enhancer ABC_E6900 Neighboring gene thymopoietin Neighboring gene STARR-positive B cell enhancer ABC_E5165 Neighboring gene STARR-seq mESC enhancer starr_27543 Neighboring gene STARR-seq mESC enhancer starr_27545 Neighboring gene nuclear encoded tRNA aspartic acid 16 (anticodon GTC) Neighboring gene nuclear encoded tRNA trytophan 2 (anticodon CCA)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
solute carrier family 25 member 3
Names
phosphate carrier protein, mitochondrial
phosphate transport protein
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133668.4NP_598429.1  solute carrier family 25 member 3 precursor

    See identical proteins and their annotated locations for NP_598429.1

    Status: VALIDATED

    Source sequence(s)
    AK077274, AK150641, BP769168
    Consensus CDS
    CCDS24121.1
    UniProtKB/Swiss-Prot
    Q542V7, Q8VEM8
    UniProtKB/TrEMBL
    Q3THU8, Q3U995, Q3UB63
    Related
    ENSMUSP00000075987.7, ENSMUST00000076694.13
    Conserved Domains (2) summary
    PTZ00169
    Location:66332
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:59147
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    90952436..90959902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513371.5XP_006513434.1  solute carrier family 25 member 3 isoform X1

    See identical proteins and their annotated locations for XP_006513434.1

    UniProtKB/TrEMBL
    G5E902, Q3THU8, Q3U995, Q3UB63
    Related
    ENSMUSP00000127098.2, ENSMUST00000170810.8
    Conserved Domains (1) summary
    pfam00153
    Location:60146
    Mito_carr; Mitochondrial carrier protein