Format

Send to:

Choose Destination

hif-1 Hypoxia-inducible factor 1 [ Caenorhabditis elegans ]

Gene ID: 180359, updated on 6-Jul-2021

Summary

Gene symbol
hif-1
Gene description
Hypoxia-inducible factor 1
Primary source
WormBase:WBGene00001851
Locus tag
CELE_F38A6.3
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See hif-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (20780407..20785260)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Echinoderm microtubule-associated protein-like elp-1 Neighboring gene DUF19 domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Hypoxia-inducible factor 1
NP_001023891.2
  • Confirmed by transcript evidence
NP_001023892.1
  • Partially confirmed by transcript evidence
NP_001023894.2
  • Confirmed by transcript evidence
NP_001299994.1
  • Confirmed by transcript evidence
NP_001359648.1
  • Partially confirmed by transcript evidence
NP_508008.4
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20780407..20785260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028720.5NP_001023891.2  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023891.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EGD2
    Conserved Domains (3) summary
    cd00083
    Location:1066
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:94145
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam14598
    Location:236338
    PAS_11; PAS domain
  2. NM_001373210.2NP_001359648.1  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (3) summary
    smart00091
    Location:89142
    PAS; PAS domain
    pfam14598
    Location:236338
    PAS_11; PAS domain
    cl00081
    Location:1266
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
  3. NM_075607.8NP_508008.4  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508008.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EGD2
    Conserved Domains (3) summary
    cd00083
    Location:1066
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:94145
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam14598
    Location:236338
    PAS_11; PAS domain
  4. NM_001313065.3NP_001299994.1  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AXG6
    Conserved Domains (3) summary
    cd00083
    Location:258
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:86137
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam14598
    Location:228330
    PAS_11; PAS domain
  5. NM_001028723.4NP_001023894.2  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023894.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EGD2
    Conserved Domains (3) summary
    cd00083
    Location:258
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:86137
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam14598
    Location:228330
    PAS_11; PAS domain
  6. NM_001028721.6NP_001023892.1  Hypoxia-inducible factor 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023892.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EGD2
    Conserved Domains (2) summary
    cd00130
    Location:1796
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam14598
    Location:20122
    PAS_11; PAS domain
Support Center