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slc-25A46 Solute carrier family 25 member 46 [ Caenorhabditis elegans ]

Gene ID: 173212, updated on 18-Sep-2024

Summary

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Official Symbol
slc-25A46
Official Full Name
Solute carrier family 25 member 46
Primary source
WormBase:WBGene00012740
Locus tag
CELE_Y40B1B.8
See related
AllianceGenome:WB:WBGene00012740
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial fission. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human SLC25A46 (solute carrier family 25 member 46). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (13428913..13434611)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene Coiled-coil domain-containing protein 86 Neighboring gene ncRNA Neighboring gene Eukaryotic translation initiation factor 3 30 kDa subunit Neighboring gene ncRNA Neighboring gene Lysine-specific histone demethylase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mitochondrial fission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial membrane fission IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Solute carrier family 25 member 46
NP_493364.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    13428913..13434611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060963.9 → NP_493364.1  Solute carrier family 25 member 46 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493364.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2J0
    Conserved Domains (2) summary
    pfam00153
    Location:291 → 385
    Mito_carr; Mitochondrial carrier protein
    cl00216
    Location:351 → 424
    L-asparaginase_like; Bacterial L-asparaginases and related enzymes
Nucleotide Protein
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