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ZNF883 zinc finger protein 883 [ Homo sapiens (human) ]

Gene ID: 169834, updated on 5-Jan-2022

Summary

Official Symbol
ZNF883provided by HGNC
Official Full Name
zinc finger protein 883provided by HGNC
Primary source
HGNC:HGNC:27271
See related
Ensembl:ENSG00000228623
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in brain (RPKM 3.0), heart (RPKM 1.5) and 19 other tissues See more
Orthologs
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Genomic context

See ZNF883 in Genome Data Viewer
Location:
9q32
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (112997120..113012192, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (115759400..115774472, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268054 Neighboring gene major urinary protein, pseudogene Neighboring gene ZFP37 zinc finger protein Neighboring gene family with sequence similarity 225 member B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101338.1NP_001094808.1  zinc finger protein 883

    See identical proteins and their annotated locations for NP_001094808.1

    Status: VALIDATED

    Source sequence(s)
    AK095843, AL162588
    Consensus CDS
    CCDS83401.1
    UniProtKB/Swiss-Prot
    P0CG24
    Related
    ENST00000638622.1
    Conserved Domains (3) summary
    COG5048
    Location:11377
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:4363
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:111136
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    112997120..113012192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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