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Kif13b kinesin family member 13B [ Mus musculus (house mouse) ]

Gene ID: 16554, updated on 16-Feb-2019

Summary

Official Symbol
Kif13bprovided by MGI
Official Full Name
kinesin family member 13Bprovided by MGI
Primary source
MGI:MGI:1098265
See related
Ensembl:ENSMUSG00000060012
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GAKIN; AI429803; 6030414C01; 5330429L19Rik; C130021D12Rik
Expression
Ubiquitous expression in colon adult (RPKM 13.2), cerebellum adult (RPKM 6.3) and 28 other tissues See more
Orthologs

Genomic context

See Kif13b in Genome Data Viewer
Location:
14; 14 D1
Exon count:
43
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (64652490..64809618)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (65271368..65425133)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene Mir124-1 host gene (non-protein coding) Neighboring gene microRNA 3078 Neighboring gene predicted gene, 36924 Neighboring gene non-SMC element 2 homolog (MMS21, S. cerevisiae) pseudogene Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene homeobox containing 1 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
14-3-3 protein binding ISO
Inferred from Sequence Orthology
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of axonogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
axon ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microvillus ISO
Inferred from Sequence Orthology
more info
 
paranode region of axon ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
kinesin-like protein KIF13B
Names
N-3 kinesin
kinesin 13B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081177.2NP_001074646.1  kinesin-like protein KIF13B

    Status: VALIDATED

    Source sequence(s)
    AC105979, AC132602
    Consensus CDS
    CCDS36954.1
    UniProtKB/TrEMBL
    E9Q4K7
    Related
    ENSMUSP00000098041.4, ENSMUST00000100473.4
    Conserved Domains (10) summary
    smart00129
    Location:6360
    KISc; Kinesin motor, catalytic domain. ATPase
    COG1716
    Location:459573
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:447544
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01365
    Location:4360
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam01302
    Location:17201783
    CAP_GLY; CAP-Gly domain
    pfam12423
    Location:756802
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12201278
    DUF3694; Kinesin protein
    pfam16183
    Location:357469
    Kinesin_assoc; Kinesin-associated
    cl14603
    Location:888952
    C2; C2 domain
    cl23748
    Location:10731143
    DUF3585; Protein of unknown function (DUF3585)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    64652490..64809618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518622.2XP_006518685.1  kinesin-like protein KIF13B isoform X5

    Conserved Domains (9) summary
    smart00129
    Location:6360
    KISc; Kinesin motor, catalytic domain. ATPase
    COG1716
    Location:459573
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:447544
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01365
    Location:4360
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:756802
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12201278
    DUF3694; Kinesin protein
    pfam16183
    Location:357469
    Kinesin_assoc; Kinesin-associated
    cl14603
    Location:888952
    C2; C2 domain
    cl23748
    Location:10731143
    DUF3585; Protein of unknown function (DUF3585)
  2. XM_006518619.3XP_006518682.1  kinesin-like protein KIF13B isoform X1

    UniProtKB/TrEMBL
    A0A286YCV9
    Related
    ENSMUSP00000153168.1, ENSMUST00000224503.1
    Conserved Domains (10) summary
    smart00129
    Location:6360
    KISc; Kinesin motor, catalytic domain. ATPase
    COG1716
    Location:459573
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:447544
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01365
    Location:4360
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam01302
    Location:17241787
    CAP_GLY; CAP-Gly domain
    pfam12423
    Location:756802
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12201278
    DUF3694; Kinesin protein
    pfam16183
    Location:357469
    Kinesin_assoc; Kinesin-associated
    cl14603
    Location:888952
    C2; C2 domain
    cl23748
    Location:10731143
    DUF3585; Protein of unknown function (DUF3585)
  3. XM_006518620.3XP_006518683.1  kinesin-like protein KIF13B isoform X2

    Conserved Domains (10) summary
    smart00129
    Location:6360
    KISc; Kinesin motor, catalytic domain. ATPase
    COG1716
    Location:459573
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:447544
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01365
    Location:4360
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam01302
    Location:17031766
    CAP_GLY; CAP-Gly domain
    pfam12423
    Location:756802
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12201278
    DUF3694; Kinesin protein
    pfam16183
    Location:357469
    Kinesin_assoc; Kinesin-associated
    cl14603
    Location:888952
    C2; C2 domain
    cl23748
    Location:10731143
    DUF3585; Protein of unknown function (DUF3585)
  4. XM_017315888.1XP_017171377.1  kinesin-like protein KIF13B isoform X3

  5. XM_006518621.3XP_006518684.1  kinesin-like protein KIF13B isoform X4

    Conserved Domains (9) summary
    COG1716
    Location:134248
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:122219
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl22853
    Location:135
    Motor_domain; Myosin and Kinesin motor domain
    pfam01302
    Location:13991462
    CAP_GLY; CAP-Gly domain
    pfam12423
    Location:431477
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:895953
    DUF3694; Kinesin protein
    pfam16183
    Location:32144
    Kinesin_assoc; Kinesin-associated
    cl14603
    Location:563627
    C2; C2 domain
    cl23748
    Location:748818
    DUF3585; Protein of unknown function (DUF3585)
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