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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011648.1 RefSeqGene
- Range
-
4989..26301
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000789.4 → NP_000780.1 angiotensin-converting enzyme isoform 1 precursor
See identical proteins and their annotated locations for NP_000780.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1), also known as the endothelial or somatic form, represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB208971, AC113554, AK296566
- Consensus CDS
-
CCDS11637.1
- UniProtKB/Swiss-Prot
-
P12821
- UniProtKB/TrEMBL
-
B4DKH4
- Related
- ENSP00000290866.4, ENST00000290866.10
- Conserved Domains (1) summary
-
- pfam01401
Location:643 → 1221
- Peptidase_M2; Angiotensin-converting enzyme
-
NM_001178057.2 → NP_001171528.1 angiotensin-converting enzyme isoform 3 precursor
See identical proteins and their annotated locations for NP_001171528.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks multiple 5' exons and an in-frame exon in the 3' region, but has an alternate 5' exon, compared to variant 1. The resulting isoform (3) is shorter, and has a distinct N-terminus and lacks an internal segment, compared to isoform 1.
- Source sequence(s)
-
AB208971, AC113554, AK301988, BM908222, M26657
- Consensus CDS
-
CCDS54155.1
- UniProtKB/Swiss-Prot
-
P12821
- Related
- ENSP00000392247.3, ENST00000413513.7
- Conserved Domains (1) summary
-
- pfam01401
Location:69 → 606
- Peptidase_M2; Angiotensin-converting enzyme
-
NM_001382700.1 → NP_001369629.1 angiotensin-converting enzyme isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC113554
-
NM_001382701.1 → NP_001369630.1 angiotensin-converting enzyme isoform 5
Status: REVIEWED
- Source sequence(s)
-
AC113554
-
NM_001382702.1 → NP_001369631.1 angiotensin-converting enzyme isoform 6
Status: REVIEWED
- Source sequence(s)
-
AC113554
-
NM_152830.3 → NP_690043.1 angiotensin-converting enzyme isoform 2 precursor
See identical proteins and their annotated locations for NP_690043.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2), also known as the testicular form, lacks multiple 5' exons, but has an alternate 5' exon, compared to variant 1. The resulting isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AB208971, AC113554, BM908222, M26657
- Consensus CDS
-
CCDS45755.1
- UniProtKB/Swiss-Prot
-
P12821
- Related
- ENSP00000290863.6, ENST00000290863.10
- Conserved Domains (1) summary
-
- pfam01401
Location:69 → 647
- Peptidase_M2; Angiotensin-converting enzyme
RNA
-
NR_168483.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC113554
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p13 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p13 Primary Assembly
- Range
-
63477061..63498373
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006721737.3 → XP_006721800.2 angiotensin-converting enzyme isoform X1
- Conserved Domains (1) summary
-
- pfam01401
Location:89 → 667
- Peptidase_M2; Angiotensin-converting enzyme
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_152831.1: Suppressed sequence
- Description
- NM_152831.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.